The Electron Microscopy Data Bank (EMDB) is a public repository for cryogenic-sample Electron Microscopy (cryoEM) volumes and representative tomograms of macromolecular complexes and subcellular structures. It covers a variety of techniques, including single-particle analysis, helical reconstruction, electron tomography, subtomogram averaging, and electron crystallography. More...
As of 22 January 2025, EMDB contains 41997 entries (latest entries, trends).
EMDB News
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06 January 2024: We are delighted to share that EMDB has officially been elevated to a Core Data Resource by ELIXIR, recognising it as a European data resource of fundamental importance to the wider life-science community and the long-term preservation of biological data.
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22 November 2023: We are happy to share the most recent version of the EMDB Nucleic Acids Research paper. The paper describes recent developments and future plans of the EMDB in the context of the worldwide Protein Data Bank. Check it out now! https://doi.org/10.1093/nar/gkad1019
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(Show all)Cryo-EM structure of human monomeric APJR-Gi complex with apelin-13.
Cryo-EM structure of simian rotavirus SA11 TLP in complex with nAb 41# (37 degree Celsius, 1 h)
Homo sapiens Xenotropic and Polytropic Retrovirus Receptor 1 (XPR1) with Y22A/E23A/K26A mutations
Cryo-EM map of p97 cross-linked with ZFAND1 with three of the six NTDs resolved in the NTD-up conformation.
Cryo-EM structure of human dimeric APJR complex with antagonistic antibody
The Composite Cryo-EM Structure of the Portal Vertex of Bacteriophage FCWL1
The Capsid Body in the Asymmetric Reconstruction of the Portal Vertex of Bacteriophage FCWL1
Cryo-EM structure of Arabidopsis thaliana phosphate transporter PHO1;H1
Structure of human 18_14D scFv and 1G01 scFv in complex with influenza virus neuraminidase from A/Yunan/DQ001/2016 (H5N6)
The Asymmetric Reconstruction of the Portal Vertex of Phage FCWL1 Before Multibody Refinement
Cryo-EM structure of photosynthetic LH1-RC core complex of Roseospirillum parvum
The Head-to-Tail interface body in the Asymmetric Reconstruction of the Portal Vertex of Bacteriophage FCWL1
Cryo-EM structure of a human-infecting bovine influenza H5N1 hemagglutinin complexed with avian receptor analog LSTc
Cryo-EM structure of a human-infecting bovine influenza H5N1 hemagglutinin complexed with avian receptor analog LSTa
Cryo-EM structure of photosynthetic LH1' complex of Roseospirillum parvum
Cryo-EM structure of neutralizing antibody 8G3 in complex with BA.1 RBD
Cryo-EM structure of the EXS domain of Arabidopsis thaliana phosphatetransporter PHO1;H1
Inner ring of the nuclear pore complex from Nup133-deficient mouse embryonic stem cell
Cryo-EM structure of the C terminal region of PTX3 with a section of coiled-coil
SARS-CoV-2 M protein dimer (short form) in complex with Fab-B and CIM-834
CryoEM Reconstruction of Yeast ADP-Actin Filament at 2.5 A resolution.
Nuclear ring of the nuclear pore complex from wild-type neural progenitors differentiated from mES cells
Nuclear ring of the nuclear pore complex from Nup133-deficient neural progenitors differentiated from mES cells
Pooled 50S subunit C_(L22)- precursor states supplemented with Api137 - Alternative PET exit Api137
Pyrococcus abyssi PolD-Rpa2 winged helix domain complex class 2 DP1 subunit local refinement
Cytoplasmic ring of the nuclear pore complex from Nup133-deficient mouse embryonic stem cell
Pooled 50S subunit C-CP_(L22)-~H61 precursor states supplemented with Api137
Cytoplasmic ring of the nuclear pore complex from wild-type neural progenitors differentiated from mES cells
Inner ring of the nuclear pore complex from Nup133-deficient neural progenitors differentiated from mES cells
Nuclear ring of the nuclear pore complex from Nup133-deficient mouse embryonic stem cell
Inner ring of the nuclear pore complex from wild-type mouse embryonic stem cell
Pooled 50S subunit C_(L22)-~H61 precursor states supplemented with Api137
SARS-CoV-2 M protein dimer (long form) in complex with Fab-E and incubated with CIM-834
Pooled 50S subunit C-CP_L2-L28 precursor states supplemented with Api137
Nuclear ring of the nuclear pore complex from wild-type mouse embryonic stem cell
Inner ring of the nuclear pore complex from wild-type neural progenitors differentiated from mES cells
Pooled 50S subunit C_(L22)- precursor states supplemented with Api137 - Canonical PET exit Api137
In situ structure of cytoplasmic microtubule of Chlamydomonas reinhardtii
Cytoplasmic ring of the nuclear pore complex from wild-type mouse embryonic stem cell
Cytoplasmic ring of the nuclear pore complex from Nup133-deficient neural progenitors differentiated from mES cells
Pooled 50S subunit d126_(L29)-/(L22)- precursor states supplemented with Api137
The cryo-EM structure of the yeast Dmc1 filament bound to ssDNA in the presence of ATP
Human proton sensing receptor GPR65 in complex with miniGs - focused map of 7TM
SARS-CoV-2 Wuhan Spike ectodomain in complex with human polyclonal antibody ModWu-RBD1 (mRNA-1273 vaccine)
Native human GABAA receptor of beta3-alpha1-gamma2-beta3-alpha2 assembly
Native human GABAA receptor of beta3-alpha1-gamma2-beta2-alpha2 assembly
Vitamin K-dependent gamma-carboxylase with factor X propeptide and glutamate-rich region and with vitamin K hydroquinone
Alkalihalobacillus halodurans (Aha) trp RNA binding attenuation protein (TRAP) mutant dTRAP with Trp
Native human GABAA receptor of beta2-alpha1-beta2-alpha3-gamma2 assembly
CryoEM structure of BoNT-NTNH-OrfX2 complex from Clostridium botulinum E1, double-binding class
TRiC-ADP-S2 state is a conformation when TRiC incubated in 1 mM ADP
Structure of mycobacterial NDH2 (type II NADH:quinone oxidoreductase)
Human excitatory amino acid transporter 3 (EAAT3) with bound L-Cysteine in an intermediate outward facing state (slight upper position)
Native human GABAA receptor of beta2-alpha1-beta2-alpha2-gamma2 assembly
EAAT3 in 200 mM NaCl and 10 mM R-2-hydroxyglutarate buffer at OFS.
Alkalihalobacillus halodurans (Aha) trp RNA binding attenuation protein (TRAP) mutant T49A/T52A dTRAP with Trp
Native human GABAA receptor of beta3-alpha1-beta2-alpha2-gamma2 assembly
Native human GABAA receptor of beta2-alpha1-beta2-alpha1-gamma2 assembly
Vitamin K-dependent gamma-carboxylase with factor IX propeptide and glutamate-rich region and with vitamin K hydroquinone
Vitamin K-dependent gamma-carboxylase with TMG2 propeptide and glutamate-rich region
Native human GABAA receptor of beta2-alpha1-beta3-alpha1-gamma2 assembly
Human GABAA receptor of beta2-alpha1-beta2-alpha1-gamma2 subtype in complex with GABA plus Lamotrigine
Human excitatory amino acid transporter 3 (EAAT3) with bound D-Aspartate in an intermediate outward facing state
Native human GABAA receptor of beta2-alpha1-beta3-alpha2-gamma2 assembly
SARS-CoV-2 Wuhan Spike ectodomain in complex with human polyclonal antibody ModWu-NTD2 (mRNA-1273 vaccine)
Vitamin K-dependent gamma-carboxylase with factor IX propeptide and partially carboxylated glutamate-rich region and with vitamin K hydroquinone and calcium
Human ACKR3 phosphorylated by GRK5 in complex with Arrestin3 reconstructed without receptor/micelle
Cryo-EM structure of the mouse TRPM3 alpha 2 channel in complex with the neurosteroid pregnenolone sulfate and the synthetic agonist CIM 0216
SARS-CoV-2 Delta Spike ectodomain in complex with human polyclonal antibody ModDe-NTD1 (mRNA-1273 vaccine)
Human ACKR3 phosphorylated by GRK2 in complex with Arrestin2 in nanodisc
Native human GABAA receptor of beta2-alpha1-beta1-alpha2-gamma2 assembly
PRC2 AJ119-450 bound to JARID2 113-121,R115A peptide and unmodified nucleosome
SARS-CoV-2 Wuhan Spike ectodomain in complex with human polyclonal antibody ModWu-NTD3 (mRNA-1273 vaccine)
SARS-CoV-2 Wuhan Spike ectodomain in complex with human polyclonal antibody ModWu-NTD4 (mRNA-1273 vaccine)
Native human GABAA receptor of beta2-alpha1-gamma2-beta2-alpha2 assembly
Cryo-EM structure of the mouse TRPM3 alpha 2 channel in complex with cholesteryl hemisuccinate
Vitamin K-dependent gamma-carboxylase with protein C propeptide and glutamate-rich region and with vitamin K hydroquinone
Cryo-EM of helical fibers formed by two peptides Pyn-K6 and Pyn-(EY)3
E. coli 50S ribosomal subunit in complex with PrAMP rumicidin-2 (focused refinement)
SARS-CoV-2 Delta Spike ectodomain in complex with human polyclonal antibody ModDe-RBD1 (mRNA-1273 vaccine)
Cryo-EM Structural Analysis of Human Integrin Heterodimer bound to DNA Aptamer
CryoEM structure of BoNT-NTNH-OrfX2 complex from Clostridium botulinum strain A1-ST7B, major class
CryoEM structure of BoNT-NTNH-OrfX2 complex from Clostridium botulinum E1, major class
TRiC-ADP-S5 state is a conformation when TRiC incubated in 1 mM ADP
SARS-CoV-2 Wuhan Spike ectodomain in complex with human polyclonal antibody ModWu-NTD1 (mRNA-1273 vaccine)
Human excitatory amino acid transporter 3 (EAAT3) monomer in 200 mM NaCl, 10 mM L-Cysteine at IFS
Cryo-EM structure of yeast Rad51 nucleoprotein filament bound to Hed1
Human excitatory amino acid transporter 3 (EAAT3) with bound L-Cysteine in an intermediate outward facing state
Cryo-EM structure of yeast Rad51 nucleoprotein filament bound to Rad54peptide
CryoEM structure of BoNT-NTNH-OrfX2 complex from Clostridium botulinum E1, minor class
Vitamin K-dependent gamma-carboxylase with TMG2 propeptide and glutamate-rich region and with vitamin K hydroquinone
40S Head Local Refinement from 80S Non-Rotated Consensus, from VacV infected cells
Human ACKR3 phosphorylated by GRK2 in complex with Arrestin3 reconstructed without receptor/micelle
SARS-CoV-2 Wuhan Spike ectodomain in complex with human polyclonal antibody ModWu-NTD5 (mRNA-1273 vaccine)
Human excitatory amino acid transporter 3 (EAAT3) with bound L-Aspartate in an intermediate outward facing state
Structure of mycobacterial NDH2 (type II NADH:quinone oxidoreductase) with 2-mercapto-quinazolinone inhibitor.
Cryo-EM structure of TAP binding protein related (TAPBPR) in complex with HLA-A*02:01 bound to a suboptimal peptide.
SARS-CoV-2 Wuhan Spike ectodomain in complex with human polyclonal antibody ModWu-RBD2 (mRNA-1273 vaccine)
CryoEM structure of BoNT-NTNH-OrfX2 complex from Clostridium botulinum strain A1-ST7B, minor class
Cryo-EM structure of the mouse TRPM3 alpha 2 channel in complex with primidone
Native human GABAA receptor of beta2-alpha1-beta1-beta1-gamma2 assembly
cryoEM structure of human ACKR3 phosphorylated by GRK5 in complex with Arrestin3 variant with the C edge loop from Arrestin2 inserted
SapNP Reconstituted Human ABCB1 bound to Taxol in presence of ATP
SapNP reconstituted Human ABCB1 in complex with Zosuquidar and ATP/Mg
SARS-CoV-2 Wuhan Spike ectodomain in complex with human polyclonal antibody ModWu-NTD6 (mRNA-1273 vaccine)
Human ACKR3 with C tail extended by 12 glycines phosphorylated by GRK5 in complex with Arrestin2 reconstructed without receptor/micelle
Native human GABAA receptor of beta2-alpha1-gamma2-beta1-alpha2 assembly
H3K36me3-modified nucleosome bound to PRC2_AJ1-450 with histone H3 tail disengaged
Human excitatory amino acid transporter 3 (EAAT3) with bound L-Cysteine in an outward facing state
Alkalihalobacillus halodurans (Aha) trp RNA binding attenuation protein (TRAP) mutant dTRAP without Trp
Cryo-EM map of p97 cross-linked with ZFAND1 with one of the six NTDs resolved in the NTD-down conformation.
Cryo-EM structure of human 26S RP (Ed state) bound to K11/K48-branched ubiquitin (Ub) chain composed of four Ub.
Cryo-EM map of p97 cross-linked with ZFAND1 reconstructed with C6 symmetry.
Cryo-EM structure of the anamorelin-bound ghrelin receptor and Gq complex
Cryo-EM structure of CX1 receptor binding domain in complex with human ACE2
Cryo-EM structure of the aspartate:alanine antiporter AspT mutant L60C
Cryo-EM structure of human dimeric APJR-Gi complex with apelin-13.
GluN1b-GluN2D NMDA receptor in complex with competitive antagonist R-CPP and allosteric inhibitor YY-23
Wild type Homo sapiens Xenotropic and Polytropic Retrovirus Receptor 1 (XPR1)