The Electron Microscopy Data Bank (EMDB) is a public repository for cryogenic-sample Electron Microscopy (cryoEM) volumes and representative tomograms of macromolecular complexes and subcellular structures. It covers a variety of techniques, including single-particle analysis, helical reconstruction, electron tomography, subtomogram averaging, and electron crystallography. More...
As of 11 November 2026, EMDB contains 64332 entries (latest entries, trends).
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New tools support deposition of structures to the wwPDB directly from structure determination software packages.
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All EMBL-EBI data resources together lead to an estimated £11.8bn/year in research productivity gains. These data also drive developments in technologies like AlphaFold, cryoSPARC and modelAngelo. We are privileged to be part of that. Read about the report and case studies here >
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Publication: Chart builder: an interactive tool for user driven data visualization in the electron microscopy data bank. Fonseca N et al. (2026) Front. Bioinform. doi: 10.3389/fbinf.2026.1763403
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Structure of a tau(297-407)-4D filament grown in potassium citrate buffer for 4 days (polymorph 1)
Structure of a tau(297-407)-4D filament grown in potassium citrate buffer for 42 days (polymorph 3)
Bovine sperm cell with gold-labeled PAP(248-286) synthetic amyloid fibrils (1 of 2)
Structure of a tau(297-407)-4D filament grown in potassium citrate buffer for 42 days (polymorph 2)
Structure of a tau(297-407)-4D filament grown in potassium citrate buffer for 42 days (polymorph 1)
Bovine sperm cell with gold-labeled PAP(248-286) synthetic amyloid fibrils (2 of 2)
Arabidopsis thaliana V-type ATPase, State 1 bound to OXR5, consensus map
Arabidopsis thaliana V-type ATPase subunits C, H and peripheral stalks focused map
Arabidopsis thaliana V-type ATPase, State 1 bound to OXR5, V1 focused map
E2 Refolding into Soluble Protein after Dissociation from Viral Membrane and E1 during Sindbis Virus Fusion
Arabidopsis thaliana V-type ATPase, State 1 bound to OXR5, c-ring focused map
Two TraI relaxases in their asymmetric homodimer state in complex with fork DNA (TraI-AHD)
Subtomogram average of A10 trimers contacting the outer surface of the vaccinia virus pore complex (untreated condition)
TraI relaxase in its helicase state in complex with fork DNA (TraI-HEL)
TraI310-1756 monomer in its helicase state in complex with fork DNA
Cryo-EM structure of the y LAT1/CD98hc heteromeric complex bound to L-glutamine
Subtomogram average of A10 trimers contacting the outer surface of the vaccinia virus pore complex (transcription condition)
Subtomogram average of Vaccinia A10 trimer from in vitro cores (transcription condition)
Focussed map of the helicase core of the TraI relaxase in complex with fork DNA (TraI-HEL-FOC)
AD PHF tau filament from AD Case 1 (2-start helical reconstruction)
Structure of the occluded-state soluble domain of human Adenylyl cyclase 9 in complex with stimulatory G protein
AD PHF tau filament from AD Case 2 (2-start helical reconstruction)
u-AD PHF tau filament from AD Case 2 (2-start helical reconstruction)
u-VT PHF tau filament from VT Case 1 (2-start helical reconstruction)
u-AD PHF tau filament from AD Case 1 (2-start helical reconstruction)
Cryo-ET reconstruction of glutaraldehyde-inactivated, wild-type mouse hepatitis virus particles
Cryo-ET reconstruction of glutaraldehyde-inactivated mouse hepatitis virus particles carrying His1322Ala and Glu1324Ala substitutions in the spike protein
Cryo-ET reconstruction of glutaraldehyde-inactivated mouse hepatitis virus particles carrying Ser1320Lys substitution in the spike protein
hnRNPA2 low complexity domain fibril structure determined by cryo-EM
hnRNPA2 low complexity domain fibril structure determined by cryo-EM with alternate N and C-termini
Cryo-EM structure of Orb2 amyloid from 30-day-old Drosophila (4Ha)
Cryo-EM structure of Orb2 amyloid from 15-day-old Drosophila (post-3Hb)
Cryo-EM structure of Orb2 amyloid from 30-day-old Drosophila (4Hc)
Cryo-EM structure of Orb2 amyloid from 30-day-old Drosophila (4Hb)
Cryo-EM structure of Orb2 amyloid from 15-day-old Drosophila (post-3Ha)
Cryo-EM structure of enterohemorrhagic Escherichia coli CdiA-CT:Tu(GTP):Ts:tRNA complex
30e (acquisition time) dose apoferritin reconstruction using RELION
40e (acqusition time) dose apoferritin reconstruction using RELION
60e (acquisition time) dose apoferritin reconstruction using RELION
Cryo-EM structure of an N-terminal deletion mutant of AGAP001487 in a nanodisc
20e (acquisition time) dose apoferritin reconstruction using RELION
10e (acqusition time) dose apoferritin reconstruction using RELION
50e (acquisition time) dose apoferritin reconstruction using RELION
Consensus map of substrate engaged p97 in complex with Ufd1/Npl4 and C-terminal FAF1-State I
CryoEM structure of substrate engaged p97 in complex with Ufd1/Npl4 and C-terminal FAF1-State I
Cryo-EM map of mosquito OPN3 in complex with the Gi heterotrimer, focused on the receptor
Cryo-EM structure of mosquito OPN3 in complex with the Gi heterotrimer
Cryo-EM structure of human PRIMPOL bound to the CMG helicase - Focus EM volume of PRIMPOL
Cryo-EM structure of human PRIMPOL bound to the CMG helicase - Focus EM volume of MCM C-tier
Tetrahymena Ribozyme L-16 complex with small molecule inhibitor ZPT-005
In situ 80S ribosome from intact HEK293T cells - consensus map of 60S region
Cryo-EM structure of human organic solute transporter OSTalpha/beta
CryoEM structural of taurocholic acid bound OST alpha/beta transporter
Cryo-EM structure of human PRIMPOL bound to the CMG helicase - Consensus EM volume
Cryo-EM structure of human PRIMPOL bound to the CMG helicase - Focus EM volume of MCM N-tier, GINS, CDC45
Cryo-electron tomography of a synapse in cultured rat hippocampal neurons
In situ portimine A-bound human pre-60S ribosome from intact HEK293T cells
Cryo-EM structure of a PSI supercomplex in the leaves of Hevea brasiliensis
Cryo-EM structure of a PSI supercomplex in the leaves of Hevea brasiliensis
Structure of the RND transporter MexB in complex with the reference inhibitor phenylalanine-arginine beta-naphthylamide.
Cryo-ET reconstruction of broken mutant Arabidopsis mitochondrion
Subtomogram averaging map of mutant Arabidopsis mitochondrial ATP synthase
Structure of hTRPC3 T561A mutant in the partially open state with C4 symmetry
Subtomogram averaging map of Arabidopsis mitochondrial ATP synthase
Cryo-EM structure of the tail-fully-disengaged TamAB complex from local refinement of the tail region
Cryo-ET of Cryo-FIB milled VeroE6 cells transfected with SARS-CoV-2 S, M, N, E-deltaH2
Cryo-ET of cry-FIB milled VeroE6 cells transfected with SARS-CoV-2 S,M, N and nsp3-4
Cryo-ET of VeroE6 cell transfected with S,M,N; E and nsp3-4 proteins from SARS-CoV-2
Closed TRiC (class 3) in the cytoplasm of HEK293 stable cell lines
Closed TRiC (class 1) in the cytoplasm of HEK293 stable cell lines
Open TRiC with two PFDs in the nucleus of HEK293 stable cell lines
Open TRiC with one PFD in the nucleus of HEK293 stable cell lines
Open TRiC without PFD in the cytoplasm of HEK293 stable cell lines
Toxoplasma gondii cytochrome c oxidase from the respiratory supercomplex III2-IV
Closed TRiC (D8 symmetry) in the cytoplasm of HEK293 stable cell lines
Open TRiC with two PFDs in the cytoplasm of HEK293 stable cell lines
Open TRiC with one PFD in the cytoplasm of HEK293 stable cell lines
CRYO-EM STRUCTURE OF EKVX HUMAN CANCER CELL LINE RIBOSOME : CLASS 4