The Electron Microscopy Data Bank (EMDB) is a public repository for cryogenic-sample Electron Microscopy (cryoEM) volumes and representative tomograms of macromolecular complexes and subcellular structures. It covers a variety of techniques, including single-particle analysis, helical reconstruction, electron tomography, subtomogram averaging, and electron crystallography. More...
As of 28 October 2026, EMDB contains 63747 entries (latest entries, trends).
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New tools support deposition of structures to the wwPDB directly from structure determination software packages.
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All EMBL-EBI data resources together lead to an estimated £11.8bn/year in research productivity gains. These data also drive developments in technologies like AlphaFold, cryoSPARC and modelAngelo. We are privileged to be part of that. Read about the report and case studies here >
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Publication: Chart builder: an interactive tool for user driven data visualization in the electron microscopy data bank. Fonseca N et al. (2026) Front. Bioinform. doi: 10.3389/fbinf.2026.1763403
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Atomic structure of the ASFV virus early transcription factor in DR state
Atomic structure of the ASFV virus early transcription factor in ER state
The targeting of non-fibrillar polyQ via distinct VCP-proteasome coupling
The targeting of non-fibrillar polyQ via distinct VCP-proteasome coupling
Cryo-EM structure of the Vo domain of Concanamycin A-bound V-ATPase from rat brain, state 1
Structure of bacteriophage T5 L-shaped tail fiber : fiber domain distal map
Structure of bacteriophage T5 L-shaped tail fiber : fiber domain consensus map
The targeting of non-fibrillar polyQ via distinct VCP-proteasome coupling
Structure of bacteriophage T5 L-shaped tail fiber : fiber domain proximal map
Cryo-EM structure of Rysto resistosome in complex with PVY coat protein
Cryo-EM structure of the Vo domain of Concanamycin A-bound V-ATPase on rat synaptic vesicles, state 2
Cryo-EM structure of the V1 domain of V-ATPase from rat brain, state 1
Cryo-EM structure of the Vo domain of V-ATPase from rat brain, state 1
Cryo-EM structure of the Vo domain of Concanamycin A-bound V-ATPase from rat brain, state 1-2
Cryo-EM structure of the Vo domain of Concanamycin A-bound V-ATPase from rat brain, state 1-3
Cryo-EM structure of the Vo domain of V-ATPase from rat brain, state 3
Cryo-EM structure of the Vo domain of Bafilomycin A1-bound V-ATPase from rat brain, state 2
Cryo-EM structure of the Vo domain of Concanamycin A-bound V-ATPase from rat brain, state 3
Cryo-EM structure of the V1 domain of V-ATPase from rat brain, state 2
Cryo-EM structure of the Vo domain of Concanamycin A-bound V-ATPase on rat synaptic vesicles, state 1
Cryo-EM structure of the Vo domain of V-ATPase from rat brain, state 2
Cryo-EM structure of the Vo domain of Bafilomycin A1-bound V-ATPase from rat brain, state 3
Cryo-EM structure of the Vo domain of Concanamycin A-bound V-ATPase on rat synaptic vesicles, state 3
Cryo-EM structure of the V1 domain of V-ATPase from rat brain, state 3
Cryo-EM structure of the Vo domain of Concanamycin A-bound V-ATPase from rat brain, state 1-1
Cryo-electron tomogram of endolysosomes in GPN-treated U2OS cells, tomogram 3
Cryo-EM structure of the Vo domain of Concanamycin A-bound V-ATPase from rat brain, state 2-2
Cryo-EM structure of the Vo domain of Concanamycin A-bound V-ATPase from rat brain, state 2-1
Cryo-EM structure of the Vo domain of bafilomycin A1-bound V-ATPase from rat brain, state 1
Cryo-EM structure of the Vo domain of Concanamycin A-bound V-ATPase from rat brain, state 2
Cryo-EM structure of the Vo domain of Concanamycin A-bound V-ATPase from rat brain, state 3-2
Cryo-EM structure of the Vo domain of Concanamycin A-bound V-ATPase from rat brain, state 3-1
Cryo-electron tomogram of endolysosomes in GPN-treated U2OS cells, tomogram 2
Cryo-electron tomogram of endolysosomes in GPN-treated U2OS cells, tomogram 1
Cryo-electron tomogram of endolysosomes in mock-treated U2OS cells, tomogram 1
Cryo-electron tomogram of endolysosomes in LLOMe-treated U2OS cells, tomogram 2
Cryo-electron tomogram of endolysosomes in LLOMe-treated U2OS cells, tomogram 1
Cryo-electron tomogram of endolysosomes in mock-treated U2OS cells, tomogram 2
Cryo-electron tomogram of endolysosomes in mock-treated U2OS cells, tomogram 3
Cryo-electron tomogram of endolysosomes in LLOMe-treated U2OS cells, tomogram 3
Cryo-EM structure of CDK2/CyclinE bound to a lysine covalent inhibitor
Cryo-EM structure of the human adenosine A2A receptor bound to the antagonist ZM-241385 resolved via the fusion/crosslinking strategy
Cryo-EM structure of the human adenosine A2A receptor in ligand free state resolved using the fusion/crosslinking strategy
Cryo-EM structure of the prostaglandin D2 receptor 1 (DP1) bound to the antagonist laropiprant resolved via the fusion/crosslinking strategy
Cryo-EM structure of R. castenholzii ModBC with ATP-bound in the pre-catalytic (inward-facing) state.
Cryo-EM structure of the prostaglandin D2 receptor 1 (DP1) bound to the antagonist asapiprant resolved via the fusion/crosslinking strategy
Cryo-EM structure of human alpha1beta2gamma2 GABA(A)R in complex with puerarin at 2.2 angstrom resolution from Biortus
Cryo-EM structure of the human NK1 tachykinin receptor bound to the antagonist aprepitant resolved via the fusion/crosslinking strategy
Cryo-EM structure of the human adenosine A2A receptor bound to the agonist adenosine resolved via the fusion/crosslinking strategy
Cryo-EM structure of the human CB1 cannabinoid receptor bound to the inverse agonist taranabant resolved via the fusion/crosslinking strategy
Cryo-EM structure of R. castenholzii ModBC with ATP-bound in the pre-catalytic (outward-facing) state.
Cryo-EM structure of R. castenholzii ModBC in the post-translocation state.
cryo-EM structure of R. castenholzii molybdate transporter ModABC with molybdate in pre-translocation state.
Cryo-EM structure of R. castenholzii ModBC in the post-catalytic state.
Structure of Candida aurisglycosylphosphatidylinositol transamidase
Type A 2N4R human tau filaments induced by heparan sulfate with a single-protofilament fold
Cryo-EM structure of the dITP-bound intermediate form of the KomBC filament
Cryo-EM structure of the dITP-bound acive form of the KomBC filament
Cryo-EM structure of the Substrate-bound clpXP complex (clpX harbors the Q208A mutation in subunits B, D, and F), Class-II
Cryo-EM structure of the substrate-free clpXP complex (clpX harbors the Q208A mutation in subunits B, D, and F), Class-I
Cryo-EM structure of the Substrate-bound clpXP complex (clpX harbors the Q208A mutation in subunits B, D, and F), Class-III
Subvolume Averaging Reconstruction of Prohibitin Complexes from Mouse Embryonic Fibroblasts
Covalent molecular glue EM12-FS in complex with CRBN/DDB1 and NTAQ1
Mycobacterium tuberculosis DNA Gyrase catalytic core in complex with DNA and indole-3-acetyl-L-aspartic acid
The cryoEM structure of virus-like particles of malabaricus grouper nervous necrosis virus, a fish nodavirus that infects Epinephelus malabaricus
LRRK2 focus refinement map on RoC, COR-A, COR-B and N-lobe kinase
LRRK2 local refinement map focused on C-terminal kinase, WD40 and C12 DARPin
Soft-landed and rehydrated beta-galactosidase (most similar to native, no reference)
Cryo-EM structure of yeast EMC:Spf1 insertase:dislocase complex in digitonin
Cryo-EM structure of yeast EMC:Spf1 insertase:dislocase complex in digitonin - Spf1 component
Cryo-EM structure of hexameric apo human K293st geranylgeranyl diphosphate synthase
Local refinement map on receptor of human LPHN2 (ADGRL2)/G13 complex in lipid nanodiscs
Consensus refinement map of human LPHN2 (ADGRL2)/G13 complex in lipid nanodiscs
gp39 protein from Escherichia phage vB_EcoS_NBD2, unbent tubule, focused map 3
Cryo-EM structure of human fibrillar procollagen type I C-propeptide heterotrimer complexed with PCPE-1
Structural characterization of hibernating ribosomes in the Gram-negative pathogen Enterobacter cloacae complex
Structural characterization of hibernating ribosomes in the Gram-negative pathogen Klebsiella quasipneumoniae
Structural characterization of hibernating ribosomes in the Gram-negative pathogen Acinetobacter baumannii
Structural snapshots of F1-ATPase catalysis in drug resistant Acinetobacter baumannii reveal novel therapeutic targets - Conformation 1a
Structural snapshots of F1-ATPase catalysis in drug resistant Acinetobacter baumannii reveal novel therapeutic targets - Conformation 2b
Alpha-Synuclein Type 1m Fibrils at pH 7.0 (supersedes entry 8PK2)
Cryo-EM structure of yeast EMC:Spf1 insertase:dislocase complex in E1-ATP conformation in digitonin
Structural snapshots of F1-ATPase catalysis in drug resistant Acinetobacter baumannii reveal novel therapeutic targets - Conformation 3b
Cryo-EM structure of yeast EMC:Spf1 insertase:dislocase complex in digitonin
Structural snapshots of F1-ATPase catalysis in drug resistant Acinetobacter baumannii reveal novel therapeutic targets - Conformation 1b
Structural snapshots of F1-ATPase catalysis in drug resistant Acinetobacter baumannii reveal novel therapeutic targets - Conformation 3a
Structural snapshots of F1-ATPase catalysis in drug resistant Acinetobacter baumannii reveal novel therapeutic targets - Conformation 2a
Rigid body fitted Mycobacterium smegnatis RNAP open promoter complex with SigmaA and RbpA
The anaphase promoting complex/cyclosome (APC/C) solved in the presence of a basic-hydrophobic (BH) cryo-tide [MALKVTKNSKINAENKAKINM]
The anaphase promoting complex/cyclosome (APC/C) solved in the presence of an acidic-hydrophobic (AH) cryo-tide [MALEVTENSKINAENKAEINM]
Rigid body fitted Mycobacterium smegmatis RNA polymerase in complex with HelD, SigA and RbpA in State I
Rigid body fitted Mycobacterium smegmatis RNA polymerase in complex with HelD, SigA and RbpA in State II
Cryo-EM structure of E.coli BrxC bound to ATPrS in Dimer-1 conformation
Cryo-EM structure of E.coli BrxBCZ complex bound to ATPrS and Mg2+
Cryo-EM structure of E.coli BrxC bound to ATPrS in Dimer-2 conformation
The eukaryotic translation initiation factor 2B from Homo sapiens with a L179V mutation in the delta subunit bound to methylated ISRIB
Ciliary 96-nm repeat unit from Leishmania tarentolae, generated via cryo-electron tomography and subtomogram averaging
The eukaryotic translation initiation factor 2B from Homo sapiens with a L179V mutation in the delta subunit, I-state
The eukaryotic translation initiation factor 2B from Homo sapiens with a L179V mutation in the delta subunit bound to ISRIB
Cryo-electron tomography and subtomogram averaging of Leishmania tarentolae Central Pair Complex
The eukaryotic translation initiation factor 2B from Homo sapiens with a L179V mutation in the delta subunit, A-state
The anaphase promoting complex/cyclosome (APC/C) solved in the presence of a scrambled basic-hydrophobic (SBH) cryo-tide [KNSINMMKKAVNKTLEKAAIN]
Cryo-EM structure of glutamate mutase from Carboxydothermus hydrogenoformans in the pre-activation state
Cryo-EM structure of glutamate mutase from Carboxydothermus hydrogenoformans in the pre-activation state
Cryo-EM structure of glutamate mutase from Carboxydothermus hydrogenoformans in the pre-activation state
Cryo-EM structure of glutamate mutase from Carboxydothermus hydrogenoformans in the pre-activation state
Cryo-EM map of monomeric Photosystem I from T. vestitus BP-1 in complex with cytochrome c6
Focus refined structure of CTLH E3-MKLN1 and substrate-MKLN1 dimer
Focus refined map of ZMYND19 bound to SPRY domain of RANBP9 and Kelch propeller of MKLN1
Cryo-EM map of substrate-MKLN1 bound CTLH-MKLN1 E3 ligase assembly
Cryo-EM structure of a ZMYND19 bound to MKLN1-RANBP9-TWA1 CTLH subcomplex
Focus refined map of ZMYND19 bound to discoidin domain of substrate receptor MKLN1
Cryo-EM map of ZMYND19 bound to RANBP9-TWA1-MKLN1 subcomplex - class II
Structure of MKLN1-RANBP9-TWA1 CTLH subcomplex bound to ZMYND19 substrate
Structure of MKLN1-RANBP9-TWA1 CTLH subcomplex bound to FAM72A C-terminus
FAM72A-UNG2 bound to the discoidin domain of substrate receptor MKLN1
Cryo-EM structure of Anopheles stephensi IR8a-IR75k receptor with nonanoic acid
Cryo-EM structure of the extracellular domain of Anopheles stephensi IR8a-IR75k receptor in complex with nonanoic acid
cryo-EM structure of the extracellular domain of Anopheles stephensi IR8a-IR75k receptor in complex with octanoic acid
Cryo-EM structure of Anopheles stephensi IR8a-IR75k receptor with nonanoic acid (symmetry expanded and ECD focused)
Cryo-EM structure of the oxytocin receptor bound to nanobody Nb2H4
Cryo-EM structure of the oxytocin receptor bound to nanobody Nb2G5
Cryo-EM structure of the oxytocin receptor bound to nanobody Nb2B1
Cryo-EM structure of the oxytocin receptor bound to nanobody Nb2B11
CryoEM structure of Western equine encephalitis virus California VLP in complex with VLDLR-LA1-3
CryoEM structure of Western equine encephalitis virus California VLP in complex with VLDLR-LBD
Consensus map of human 26S proteasome in EA1-EA2 double-cap state (EMD-62091), also serving as focused map on the 20S core particle region via pseudo-single cap extraction strategy with C2/D2 symmetry
A focused map of the human 26S proteasome in the EA1-EA2 double-cap state (EMD-62091), focusing on the 19S regulatory particle region (EA1).
CryoEM structure of Western equine encephalitis virus California VLP in complex with VLDLR-LBD
Fab NORO-320 bound to C-D VP1 dimer of GII.4 Syd VLP (T=4) from C-side
Fab NORO-320 bound to C-D VP1 dimer of GII.4 Syd VLP (T=4) from D-side
2 molecules of Fab NORO-320 bound to A-A' VP1 dimer of GII.4 Syd VLP (T=1) left side
2 molecules of Fab NORO-320 bound to C-D VP1 dimer of GII.4 Syd VLP (T=4)
Fab NORO-320 bound to A-B VP1 dimer of GII.4 Syd VLP (T=4) from 5 fold axis
Fab NORO-320 bound to A-B VP1 dimer of GII.4 Syd VLP (T=4) from 6-fold axis
2 molecules of Fab NORO-320 bound to A-A' VP1 dimer of GII.4 Syd VLP (T=1) Right side
Cryo-EM structure of HalT (C23A mutant), a peptidase-domain containing ABC Transporter, with substrate
Cryo-EM structure of AcrB in liposomes in the absence of doxorubicin (Apo1-out)
Cryo-EM structure of AcrB in liposomes incubated with doxorubicin (class2b)
Cryo-EM structure of HalTWT, a peptidase-domain containing ABC Transporter, with ADP and vanadate
Cryo-EM structure of HalM1 (C963AH964A mutant), a class II lanthipeptide synthetase, bound with substrate
Cryo-EM structure of AcrB in liposomes incubated with doxorubicin (class2-in)
Cryo-EM structure of HalM2, a class II lanthipeptide synthetase, bound with substrate and ADP
Cryo-EM structure of AcrB in liposomes incubated with doxorubicin (class2a)
Cryo-EM structure of AcrB in liposomes incubated with doxorubicin (class2c)
Cryo-EM structure of SmcE, a peptidase-domain containing ABC Transporter, with substrate and ATP
Cryo-EM structure of ClassIII Lanthipeptide modification enzyme FaecKC in the presence of ATPrS.
Cryo-EM structure of SmcEWT, a peptidase-domain containing ABC Transporter, with ADP and vanadate
Cryo-EM structure of HalT (E643Q mutant), a peptidase-domain containing ABC transporter, incubated with ATP
Cryo-EM structure of HalM2, a class II lanthipeptide synthetase, bound with substrate HalA2 and Zn
Cryo-EM structure of HalT (C23A mutant), a peptidase-domain containing ABC Transporter, bound with substrate and ATP
Cryo-EM structure of HalM1, a class II lanthipeptide synthetase, bound with substrate, ATP, and Zn
Cryo-EM structure of HalT (C23A mutant), a peptidase-domain containing ABC Transporter, in an apo state
Cryo-EM structure of AcrB in liposomes incubated with doxorubicin (class1-in)
Cryo-EM structure of AcrB in liposomes incubated with doxorubicin (class1-out)
Cryo-EM structure of AcrB in liposomes in the absence of doxorubicin (Apo1-in)
Cryo-EM structure of AcrB in liposomes in the absence of doxorubicin (Apo2b)
Cryo-EM structure of AcrB in liposomes incubated with doxorubicin (class2-out)
Cryo-EM structure of AcrB in liposomes in the absence of doxorubicin (Apo2a)
Cryo-EM structure of AcrB in liposomes in the absence of doxorubicin (Apo2-in)
Cryo-EM structure of AcrB in liposomes in the absence of doxorubicin (Apo2-out)
Cryo-EM structure of AcrB in liposomes in the absence of doxorubicin (Apo2c)