EMDB (the Electron Microscopy Data Bank) is a public repository for electron cryo-microscopy maps and tomograms of macromolecular complexes and subcellular structures. It covers a variety of techniques, including single-particle analysis, electron tomography, sub-tomogram averaging, fibre diffraction and electron crystallography. More...
As of 30 November 2022, EMDB contains 23691 entries (latest entries, trends).
EMDB News
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12 October 2022: EMDB Validation Analysis (VA) is officially launched at https://www.ebi.ac.uk/emdb/va/. It is available as a local stand-alone package and is coming soon to CCP-EM. The tutorial on how to use the VA information is on EMDB YouTube channel. A full description of VA functionality is published in Acta Crystallographica Section D.
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7 June 2022: EMDB and EMPIAR have launched a dedicated YouTube channel where you can find talks, tutorials, and much more. Check it out and let us know what content you would like to see.
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Major polymorph in alpha-synuclein fibril seeded by cerebrospinal fluid from a mid-to-late stage (mid-PD-1) Parkinson's disease patient
Focused refinement of the Raptor-TFEB-Rag-Ragulator complex with c-Rag-Ragulator mask
CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (inhibited by DDM)
SARS-CoV-2 replication-transcription complex bound to ATP, in a pre-catalytic state
Structure of SNAPc:TBP-TFIIA-TFIIB sub-complex bound to U5 snRNA promoter
CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (state 1) - membrane arm
CryoEM map of the manually-picked stalled contraction intermediate state of bacteriophage A511.
A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analogue inhibitors
SARS-CoV-2 replication-transcription complex bound to GTP, in a pre-catalytic state
CryoEM structure of Arabidopsis ROS1 in complex with TG mismatch dsDNA at 3.3 Angstroms resolution
Focused refinement of the Raptor-TFEB-Rag-Ragulator complex with Raptor mask
Cryo-EM Structure of Membrane-bound Fructose Dehydrogenase from Gluconobacter japonicus
EM map of the LARGE1 dual glycosyltransferase without its coiled-coil stem region.
Type 1C alpha-synuclein fibril seeded by cerebrospinal fluid from a mid-to-late stage (mid-PD-4) Parkinson's disease patient
RuvAB branch migration motor complexed to the Holliday junction - composite map 1 and 2
Human mitochondrial ribosome small subunit in complex with streptomycin
cryo-EM structure of the mTORC1-TFEB-Rag-Ragulator complex with symmetry expansion
Cryo-EM structure of the barley Yellow stripe 1 transporter in complex with Fe(III)-DMA
CryoEM structure of Arabidopsis ROS1 in complex with a covalent-linked reaction intermediate at 3.9 Angstroms resolution
Cryo-EM structure of the barley Yellow stripe 1 transporter in complex with Fe(III)-PDMA
SARS-CoV-2 replication-transcription complex bound to UTP, in a pre-catalytic state
SARS-CoV-2 replication-transcription complex bound to CTP, in a pre-catalytic state
Cryo-EM map of DNMT1 (aa:351-1616) in complex with ubiquitinated H3
Saccharomyces cerevisiae Ufd1/Npl4/Cdc48 complex bound to two ubiquitin moieties and one unfolded ubiquitin in presence of SUMO-ubiquitin(K48polyUb)-mEOS and ATP, state 2 (uC)
V-K CAST Transpososome from Scytonema hofmanni, major configuration
Endogenous dihydrolipoamide succinyltransferase (E2) core of 2-oxoglutarate dehydrogenase complex from bovine kidney
Structure of SNAPc containing Pol II pre-initiation complex bound to U5 snRNA promoter (CC)
Cryo-EM structure of a CRISPR effector in complex with a caspase regulator
SARS-CoV-2 replication-transcription complex bound to Remdesivir triphosphate, in a pre-catalytic state
The local refined map of Omicron spike with bispecific antibody FD01
Saccharomyces cerevisiae Ufd1/Npl4/Cdc48 complex bound to three ubiquitin moieties in presence of SUMO-ubiquitin(K48polyUb)-mEOS and ATP, state 1 (intB)
CryoEM map of the CNN-picked stalled contraction intermediate state of bacteriophage A511.
Cryo-EM structure of ex vivo AA amyloid from renal tissue of a short hair cat deceased in a shelter
Minor polymorph inalpha-synuclein fibril seeded by cerebrospinal fluid from a mid-to-late stage (mid-PD-1) Parkinson's disease patient
CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (state 1)
Cryo-EM structure of the mTORC1-TFEB-Rag-Ragulator complex with C2 symmetry
Cryo-EM structure of the SARS-CoV-2 spike protein (2-up RBD) bound to neutralizing antibody NIBIC-71
Saccharomyces cerevisiae Ufd1/Npl4/Cdc48 complex bound to two folded ubiquitin moieties and one unfolded ubiquitin in presence of SUMO-ubiquitin(K48polyUb)-mEOS and ATP, state 1 (uA)
High Molecular Weight Kininogen Single Chain from Human Plasma with not completely unmasked glycosylation
V-K CAST Transpososome from Scytonema hofmanni, minor configuration
CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (inhibited by DDM) - membrane arm
Cryo-EM structure of human DNMT1 (aa:351-1616) in complex with ubiquitinated H3 and hemimethylated DNA analog (CXXC-ordered form)
Intermediate resolution structure of barley (1,3;1,4)-beta-glucan synthase CslF6.
Minor polymorph in alpha-synuclein fibril seeded by cerebrospinal fluid from a mid-to-late stage (mid-PD-4) Parkinson's disease patient
Focused refinement of the Raptor-TFEB-Rag-Ragulator complex with TFEB-nc-Rag-Ragulator mask
Saccharomyces cerevisiae Ufd1/Npl4/Cdc48 complex unbound but in the presence of SUMO-ubiquitin(K48polyUb)-mEOS and ATP
Saccharomyces cerevisiae Ufd1/Npl4/Cdc48 complex bound to two ubiquitin moieties in presence of SUMO-ubiquitin(K48polyUb)-mEOS and ATP, state 1 (intA)
Endogenous dihydrolipoamide acetyltransferase (E2) core of pyruvate dehydrogenase complex from bovine kidney
CryoEM structure of miniGq-coupled hM3R in complex with iperoxo (local refinement)
Cryo-EM structure of human DNMT1 (aa:351-1616) in complex with ubiquitinated H3 and hemimethylated DNA analog (CXXC-disordered form)
Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (OC)
CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (state 2)
CryoEM structure of Arabidopsis ROS1 in complex with 5mC-dsDNA at 3.1 Angstroms resolution
EM map of the LARGE1 dual glycosyltransferase with its coiled-coil stem region
CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (state 2) - membrane arm
Saccharomyces cerevisiae Ufd1/Npl4/Cdc48 complex bound to three ubiquitin moieties and one unfolded ubiquitin in presence of SUMO-ubiquitin(K48polyUb)-mEOS and ATP, state 2 (uD)
Cryo-EM structure of the SARS-CoV-2 spike protein (1-up RBD) bound to neutralizing antibody 7G7.2
Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (CC)