EMDB (the Electron Microscopy Data Bank) is a public repository for electron cryo-microscopy maps and tomograms of macromolecular complexes and subcellular structures. It covers a variety of techniques, including single-particle analysis, electron tomography, sub-tomogram averaging, fibre diffraction and electron crystallography. More...
As of 22 March 2023, EMDB contains 25698 entries (latest entries, trends).
EMDB News
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21 December 2022: EMDB proudly announces the EMICSS resource. It provides weekly updated cross-reference information for all EMDB entries to other resources (including PDB, EMPIAR, Europe PMC, UniProt, AlphaFold DB and many more.) Read more here: emdb-empiar.org/emicss.
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12 October 2022: EMDB Validation Analysis (VA) is officially launched at https://www.ebi.ac.uk/emdb/va/. It is available as a local stand-alone package and is coming soon to CCP-EM. The tutorial on how to use the VA information is on EMDB YouTube channel. A full description of VA functionality is published in Acta Crystallographica Section D.
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(Show all)Cryo-EM structure of Mycobacterial Type VII Secretion System Virulence Factor EspB (residues 1-332)
Mouse apoferritin from data collected on Talos Arctica microscope equipped with a K3 camera operating in super resolution mode, in 150-200 nm ice thickness
Bovine multidrug resistance protein 1 (MRP1) bound to cyclic peptide inhibitor 1 (CPI1)
Complex structure of Neuropeptide Y Y2 receptor in complex with PYY(3-36) and Gi (Consensus map)
Octahedral supramolecular assembly of the bicomponent gamma-hemolysin octameric pore complexes from Staphylococcus aureus Newman.
Structurally hetero-junctional human Cx36/GJD2 gap junction channel in soybean lipids (C1 symmetry)
Complex structure of Neuropeptide Y Y2 receptor in complex with PYY(3-36) and Gi (Focused map on PYY(3-36)-Y2R)
The SARS-CoV-2 receptor binding domain bound with the Fab fragment of a human neutralizing antibody Ab712
Structurally hetero-junctional human Cx36/GJD2 gap junction channel in soybean lipids (C6 symmetry)
Herpes simplex virus 1 polymerase holoenzyme bound to mismatched DNA in editing conformation
Complex structure of Neuropeptide Y Y2 receptor in complex with NPY and Gi (Focused map on NPY-Y2R)
Structural basis for catalysis of human choline/ethanolamine phosphotransferase (CEPT1) complexed with CDP-choline
S728-1157 IgG in complex with SARS-CoV-2-6P-Mut7 Spike protein (focused refinement)
Structure of dodecameric KaiC-RS-S413E/S414E complexed with KaiB-RS solved by cryo-EM
Mouse apoferritin from data collected on Talos Arctica microscope equipped with a K3 camera operating in super resolution mode, in 50-100 nm ice thickness
A cryo-EM structure of B. oleracea RNA polymerase V at 3.57 Angstrom
Human Oct4 bound to nucleosome with human nMatn1 sequence (focused refinement of Oct4 bound region)
Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains - KWOCA51
The SARS-CoV-2 receptor binding domain bound with the Fab fragment of a human neutralizing antibody Ab847
Complex structure of Neuropeptide Y Y2 receptor in complex with NPY and Gi (Consensus map)
Cryo-EM structure of the Arabidopsis thaliana I+III2 supercomplex (Complete conformation 1 composition)
Cryo-EM structure of the TUG891 bound GPR120-Giq complex(mask on receptor)
Human Oct4 bound to nucleosome with human nMatn1 sequence (focused refinement of nucleosome)
The SARS-CoV-2 receptor binding domain bound with the Fab fragment of a human neutralizing antibody Ab709
Complex structure of Neuropeptide Y Y2 receptor in complex with PYY(3-36) and Gi (Focused map on Gi-scFv16)
Previously uncharacterized rectangular bacteria in the dolphin mouth
Mycobacterium tuberculosis RNAP paused elongation complex with Escherichia coli NusG transcription factor
Human Cx36/GJD2 (BRIL-fused mutant) gap junction channel in detergents at 2.2 Angstroms resolution
human EMC:human Cav1.2 channel complex in GDN detergent at 3.1 Angstrom
Complex structure of Neuropeptide Y Y2 receptor in complex with NPY and Gi (Focused map on Gi-scFv16)
Mouse apoferritin from data collected on Talos Arctica microscope equipped with a K3 camera operating in super resolution mode, in 200-500 nm ice thickness
The SARS-CoV-2 receptor binding domain bound with the Fab fragment of a human neutralizing antibody Ab765
Complex structure of a small molecule (SPC-14) bound SARS-CoV-2 spike protein, closed state
Cryo-EM structure of the eicosapentaenoic acid bound GPR120-Gi1 complex(mask on Gil-scFV16 complex)
Cryo-EM structure of human ABCD1 E630Q in the presence of C26:0-CoA and ATP
Structure of SLC40/ferroportin in complex with vamifeport and synthetic nanobody Sy12 in outward-facing conformation
Structure of the human L-type voltage-gated calcium channel Cav1.2 complexed with gabapentin
Complex structure of Neuropeptide Y Y2 receptor in complex with NPY and Gi
S728-1157 IgG in complex with SARS-CoV-2-6P-Mut7 Spike protein (global refinement)
Complex structure of Neuropeptide Y Y2 receptor in complex with PYY(3-36) and Gi
Cryo-EM structure of conjugative pili from Pyrobaculum calidifontis
Alpha1/BetaB Heteromeric Glycine Receptor in 1 mM Glycine 20 uM Ivermectin State
Structure of SLC40/ferroportin in complex with synthetic nanobody Sy3 in occluded conformation
Signal peptide mimicry primes Sec61 for client-selective inhibition
Alpha1/BetaB Heteromeric Glycine Receptor in Strychnine-Bound State
Heteromeric ring comprised of peroxiredoxin from Thermococcus kodakaraensis (TkPrx) F42C/C46S/C205S/C211S mutant modified with 2-(bromoacetyl)naphthalene (Naph@TkPrx*F42C) and TkPrx C46S/F76C/C205S/C211S mutant modified with 2-(bromoacetyl)naphthalene (Naph@TkPrx*F76C) (Naph@(MIX|3:3))
Herpes simplex virus 1 polymerase holoenzyme bound to DNA and dTTP in closed conformation
Cryo-EM structure of the TUG891 bound GPR120-Giq complex(mask on Giq-scFV16 complex)
A cryo-EM structure of B. oleracea RNA polymerase V elongation complex at 2.73 Angstrom
Human Cx36/GJD2 (N-terminal deletion BRIL-fused mutant) gap junction channel in soybean lipids (C1 symmetry)
Cryo-EM structure of the eicosapentaenoic acid bound GPR120-Gi1 complex(mask on receptor)
Structure of WT E.coli ribosome 50S subunit with complexed with mRNA, P-site fMet-NH-tRNAfMet and A-site meta-aminobenzoic acid charged NH-tRNAPhe
Cutibacterium acnes 70S ribosome with mRNA, P-site tRNA and Sarecycline bound
Herpes simplex virus 1 polymerase holoenzyme bound to DNA in both open/closed conformations
Acidipropionibacterium acidipropionici encapsulin in a closed state at pH 7.5
Mouse apoferritin from data collected on Talos Arctica microscope equipped with a K3 camera operating in super resolution mode, in 0-50 nm ice thickness
Human Cx36/GJD2 (BRIL-fused mutant) gap junction channel in soybean lipids
Human L-type voltage-gated calcium channel Cav1.2 complexed with gabapentin (Segment Map)
Structure of SLC40/ferroportin in complex with vamifeport and synthetic nanobody Sy3 in occluded conformation
Herpes simplex virus 1 polymerase holoenzyme bound to DNA and acyclovir triphosphate in closed conformation
Acidipropionibacterium acidipropionici encapsulin in an open state at pH 7.5
Yeast RNA polymerase II transcription pre-initiation complex with core Mediator
Human Cx36/GJD2 (N-terminal deletion BRIL-fused mutant) gap junction channel in soybean lipids (D6 symmetry)
Mouse apoferritin from data collected on Talos Arctica microscope equipped with a K3 camera operating in super resolution mode, in 100-150 nm ice thickness
Cryo-EM structure of the RecA presynaptic filament from S.pneumoniae
CryoEM structure of synthetic tau repeat R1R2 with two acetylated lysines at positions 274 and 280
Electron cryo-tomography of the ER-mitochondria encounter structure ERMES
Cryo-EM structure of Mycobacterial Type VII Secretion System Virulence Factor EspB (residues 1-332) with Phosphatidic acid (PA)
Cryo-EM structure of human ABCD1 E630Q in the presence of ATP in inward-facing state
Acidipropionibacterium acidipropionici encapsulin in a closed state at pH 3.0
Mycobacterium tuberculosis RNAP elongation complex with NusG transcription factor
Structurally hetero-junctional human Cx36/GJD2 gap junction channel in detergents (C6 symmetry)
Structure of the human L-type voltage-gated calcium channel Cav1.2 complexed with gabapentin (consensus map)
Cryo-EM structure of the eicosapentaenoic acid bound GPR120-Gi complex(consensus map)
Structurally hetero-junctional human Cx36/GJD2 gap junction channel in detergents (C1 symmetry)
Cryo-EM structure of the TUG891 bound GPR120-Giq complex (consensus map)
Human Cx36/GJD2 gap junction channel with pore-lining N-terminal helices in soybean lipids
Human olfactory receptor OR51E2 bound to propionate in complex with miniGs399
SARS-CoV-2 Delta-RBD complexed with Fabs BA.2-36, BA.2-23, EY6A and COVOX-45
Structural basis for catalysis of human choline/ethanolamine phosphotransferase (CEPT1)
Mycobacterium tuberculosis RNAP paused elongation complex with NusG transcription factor
Cryo-EM structure of human ABCD1 E630Q in the presence of ATP and Magnesium in outward-facing state