PC68_L31_570 Fab in complex with HIV-1 Env BG505 SOSIP.664 and RM20A3 Fab (negative stain)

Cryo-EM structure of the cytochrome bc complex (CIII2) from Bacillus subtilis

PC68_L31_391 Fab in complex with HIV-1 Env BG505 SOSIP.664 and RM20A3 Fab (negative stain)

PC68_L31_570 Fab in complex with HIV-1 Env BG505 SOSIP.664 and RM20A3 Fab

High-resolution cryo-EM structure of the CIII2CIV1 respiratory supercomplex from Bacillus subtilis (composite)

Cryo-EM structure of the CIII2 featuring FES in c-position from Bacillus subtilis

Cryo-EM structure of the CIII2CIV1 respiratory supercomplex from Bacillus subtilis

Cryo-EM structure of the cytochrome bc complex (CIII2) from Bacillus subtilis with multiple Qi site menaquinone binding

High-resolution cryo-EM structure of the cytochrome bc complex (CIII2) from Bacillus subtilis (composite)

Cryo-EM structure of the CIII2 featuring FES in b-position from Bacillus subtilis

HSV1 gB prefusion-1 trimers with "deliD" mutations

HHV6B gB trimer with "deliDoP" mutations and I5350A2h (prefusion conformation) - DII-DV local refinement

CryoEM structure of the infectious flacherie virus of silkworm

Hibernating ribosome of unfed tardigrade (R. varieornatus) - eEF2, eIF5A, Cyp1 bound

Polynucleotide kinase phosphatase bound to a nucleosome containing a nick with a 3'-phosphate and 5'-OH at SHL-5 (catalytic, composite)

Polynucleotide kinase phosphatase bound to a nucleosome containing a nick with a 3'-phosphate and 5'-OH at SHL-3 (catalytic, composite)

Polynucleotide kinase phosphatase bound to a nucleosome containing a nick with a 3'-phosphate and 5'-OH at SHL-5 (catalytic-FHA, composite)

Polynucleotide kinase phosphatase bound to a nucleosome containing a nick with a 3'-phosphate and 5'-OH at SHL-3 (catalytic-FHA, composite)

Polynucleotide kinase phosphatase bound to a nucleosome containing a nick with a 3'-phosphate and 5'-OH at SHL-3 (FHA, composite)

Polynucleotide kinase phosphatase bound to a nucleosome containing a nick with a 3'-phosphate and 5'-OH at SHL-3 (catalytic, consensus)

Polynucleotide kinase phosphatase bound to a nucleosome containing a nick with a 3'-phosphate and 5'-OH at SHL-3 (catalytic-FHA, PNKP/DNA local refine)

Polynucleotide kinase phosphatase bound to a nucleosome containing a nick with a 3'-phosphate and 5'-OH at SHL-3 (catalytic-FHA, FHA local refine)

Polynucleotide kinase phosphatase bound to a nucleosome containing a nick with a 3'-phosphate and 5'-OH at SHL-5 (FHA, composite)

Polynucleotide kinase phosphatase bound to a nucleosome containing a nick with a 3'-phosphate and 5'-OH at SHL-3 (FHA, consensus)

Polynucleotide kinase phosphatase bound to a nucleosome containing a nick with a 3'-phosphate and 5'-OH at SHL-3 (catalytic, PNKP/DNA local refine)

Polynucleotide kinase phosphatase bound to a nucleosome containing a nick with a 3'-phosphate and 5'-OH at SHL-3 (catalytic-FHA, consensus)

Polynucleotide kinase phosphatase bound to a nucleosome containing a nick with a 3'-phosphate and 5'-OH at SHL-3 (FHA, FHA local refine)

Polynucleotide kinase phosphatase bound to a nucleosome containing a nick with a 3'-phosphate and 5'-OH at SHL-5 (FHA, consensus)

Polynucleotide kinase phosphatase bound to a nucleosome containing a nick with a 3'-phosphate and 5'-OH at SHL-5 (catalytic-FHA, PNKP/DNA local refine)

Polynucleotide kinase phosphatase bound to a nucleosome containing a nick with a 3'-phosphate and 5'-OH at SHL-5 (catalytic-FHA, consensus)

Polynucleotide kinase phosphatase bound to a nucleosome containing a nick with a 3'-phosphate and 5'-OH at SHL-4 (catalytic-FHA, PNKP/DNA local refine)

Polynucleotide kinase phosphatase bound to a nucleosome containing a nick with a 3'-phosphate and 5'-OH at SHL-4 (FHA, consensus)

Polynucleotide kinase phosphatase bound to a nucleosome containing a nick with a 3'-phosphate and 5'-OH at SHL-5 (catalytic, consensus)

Polynucleotide kinase phosphatase bound to a nucleosome containing a nick with a 3'-phosphate and 5'-OH at SHL-4 (catalytic-FHA, consensus)

Polynucleotide kinase phosphatase bound to a nucleosome containing a nick with a 3'-phosphate and 5'-OH at SHL-5 (catalytic, PNKP/DNA local refine)

Polynucleotide kinase phosphatase bound to a nucleosome containing a nick with a 3'-phosphate and 5'-OH at SHL-5 (FHA, FHA local refine)

Polynucleotide kinase phosphatase bound to a nucleosome containing a nick with a 3'-phosphate and 5'-OH at SHL-5 (catalytic-FHA, FHA local refine)

Cryo-EM structure of the CIII2 without YlbA from Bacillus subtilis

Cryo-EM structure of pSTAT1 bound to importin alpha 5 (4:2 assembly)

Nucleosome containing a nick with a 3'-phosphate and 5'-OH at SHL-3

Cryo-EM structure of the human mitochondrial transcription initiation complex on HSP with TFAM

Cryo-EM structure of the human mitochondrial transcription initiation complex on HSP without TFAM

Nucleosome containing a nick with a 3'-phosphate and 5'-OH at SHL-4

Polynucleotide kinase phosphatase bound to a nucleosome containing a nick with a 3'-phosphate and 5'-OH at SHL-4 (catalytic, composite)

Polynucleotide kinase phosphatase bound to a nucleosome containing a nick with a 3'-phosphate and 5'-OH at SHL-4 (catalytic-FHA, composite)

Polynucleotide kinase phosphatase bound to a nucleosome containing a nick with a 3'-phosphate and 5'-OH at SHL-4 (catalytic, consensus)

Nucleosome containing a nick with a 3'-phosphate and 5'-OH at SHL-5

Polynucleotide kinase phosphatase bound to a nucleosome containing a nick with a 3'-phosphate and 5'-OH at SHL-4 (FHA, composite)

Polynucleotide kinase phosphatase bound to a nucleosome containing a nick with a 3'-phosphate and 5'-OH at SHL-4 (catalytic, PNKP/DNA local refine)

Polynucleotide kinase phosphatase bound to a nucleosome containing a nick with a 3'-phosphate and 5'-OH at SHL-4 (FHA, FHA local refine)

Polynucleotide kinase phosphatase bound to a nucleosome containing a nick with a 3'-phosphate and 5'-OH at SHL-4 (catalytic-FHA, FHA local refine)

Cryo-EM structure of Acinetobacter baumannii LolDF bound to abaucin with lipoprotein

Cryo-EM map of Escherichia coli GroEL bound to denatured luciferase

Cryo-EM structure of full-length molybdoenzyme ergothioneine synthase from Caldithrix abyssi

Cryo-EM map of Escherichia coli GroEL

Cryo-EM structure of the persulfide-bound metallopterin-binding domain of molybdoenzyme ergothioneine synthase from Caldithrix abyssi

Cryo-EM structure of the native metallopterin-binding domain of molybdoenzyme ergothioneine synthase from Caldithrix abyssi

Cryo-EM structure of Retron-ATPaseHNH

Non-rotated 80S with eRF1(AAQ) and P/P tRNA

Rotated 80S with A/A-P/E tRNA

Cryo-EM structure of the L. pneumophila Ceg14 effector in complex with AnkJ

Cryo-EM Structure of Dimeric EcCaspase Bound to N7-cADPR

Rotated 80S with A/A'-P/E tRNA

Cryo-EM structure of the L. pneumophila Ceg14 effector in complex with G-actin and AnkJ

semi-rotated 80S with A/A-P/P tRNA

Rotated 80S with A/P-P/E tRNA

Cryo-EM Structure of Hybrid NRPS-PKS Enzyme CorA from the myxobacterium Corallococcus exiguus

Cryo-EM of the sarco(endo)plasmic reticulum calcium ATPase (SERCA) in presence of calcium and compound UM-52 (bound)

Cryo-EM of the sarco(endo)plasmic reticulum calcium ATPase (SERCA) in presence of calcium and compound UM-52 (unbound)

Cryo-EM of the sarco(endo)plasmic reticulum calcium ATPase (SERCA) in presence of calcium and CDN1163

CryoEM structure of substrate engaged p97 in complex with Ufd1/Npl4 and C-terminal FAF1- State II

CryoEM structure of substrate engaged p97 in complex with Ufd1/Npl4 and C-terminal FAF1- State III

Protein Complex(local refinement)

Consensus map of substrate engaged p97 in complex with Ufd1/Npl4 and C-terminal FAF1- State II

Focused map of substrate engaged p97 in complex with Ufd1/Npl4 and C-terminal FAF1- State II (Npl4)

Focused map of substrate engaged p97 in complex with Ufd1/Npl4 and C-terminal FAF1 (FAF1)

Focused map of substrate engaged p97 in complex with Ufd1/Npl4 and C-terminal FAF1-State I (Npl4)

Protein Complex(local refinement)

Cryo-EM structure of HKU1 spike with antibody HKU1-2 (conformation 1)

Cryo-EM structure of HKU1 spike with antibody HKU1-11 (local refinement of CTD, NTD, and Fab variable domain)

Cryo-EM structure of HKU1 spike with antibody HKU1-2 (conformation 2)

Focused map of substrate engaged p97 in complex with Ufd1/Npl4 and C-terminal FAF1- State IV (Npl4)

Focused map of substrate engaged p97 in complex with Ufd1/Npl4 and C-terminal FAF1- State III (Npl4)

CryoEM structure of substrate engaged p97 in complex with Ufd1/Npl4 and C-terminal FAF1-State II (non-normalized map)

Cryo-EM structure of Acinetobacter baylyi LolDF bound AMP-PNP (closed NBDs)

CryoEM structure of substrate engaged p97 in complex with Ufd1/Npl4 and Delta-N-FAF1

Consensus map of substrate engaged p97 in complex with Ufd1/Npl4 and C-terminal FAF1- State III

Consensus map of substrate engaged p97 in complex with Ufd1/Npl4 and C-terminal FAF1- State IV

Cryo-EM structure of Acinetobacter baumannii LolDF bound abaucin (wide cavity)

Focused map of substrate engaged p97 in complex with Ufd1/Npl4 and C-terminal FAF1- State IV (FAF1)

Cryo-EM structure of Acinetobacter baumannii LolDF bound abaucin (narrow cavity)

CryoEM structure of substrate engaged p97 in complex with Ufd1/Npl4 and C-terminal FAF1-State I (non-normalized map)

CryoEM structure of substrate engaged p97 in complex with Ufd1/Npl4 and C-terminal FAF1-State III (non-normalized map)

CryoEM structure of substrate engaged p97 in complex with Ufd1/Npl4 and C-terminal FAF1-State IV (non-normalized map)

CryoEM structure of substrate engaged p97 in complex with Ufd1/Npl4 and C-terminal FAF1- State IV

Cryo-EM structure of Acinetobacter baylyi LolA bound LolDF with lipoprotein

Cryo-EM structure of Acinetobacter baylyi endogenous LolDF with lipoprotein

Cryo-EM structure of human beta-cardiac myosin carrying the E525K mutation in the Interacting-Heads Motif state

Human beta-cardiac myosin S1 motor domain with the essential light chain in the pre-powerstroke state

Human beta-cardiac myosin S1 motor domain carrying the E525K mutation with the essential light chain in the pre-powerstroke state

Cryo-EM Structure of RSV Polymerase (L:P) Bound to Tr3-mimic RNA (TrC12-4U-Tr3), Unreacted Tr3-mimic Form B

Interferon-alpha8 complexed with IFA002 monoclonal antibody and IFNAR2, global cryoEM

Cryo-EM structure of CAS:Ran-GTP:importin alpha 5 complex

Cryo-EM Structure of RSV Polymerase (L:P) Bound to Tr3-mimic RNA (TrC12-4U-Tr3), Unreacted Tr3-mimic Form A

Cryo-EM structure of apo-pSTAT1

Cryo-EM structure of pSTAT1 bound to importin alpha 5 (2:1 assembly)

Synaptotagmin-1 molecules from the 0 mM Ca2+ Cluster 12

Cryo-EM ternary structure of CD1c presenting a mycobacterial lipid to a T cell receptor

Synaptotagmin-1 molecules from the 0 mM Ca2+ Cluster 9

Synaptotagmin-1 molecules from the 0 mM Ca2+ Cluster 3

Synaptotagmin-1 molecules from the 0 mM Ca2+ Cluster 5

Synaptotagmin-1 molecules from the 0 mM Ca2+ Cluster 10

Synaptotagmin-1 molecules from the 0 mM Ca2+ Cluster 6

Synaptotagmin-1 molecules from the 0 mM Ca2+ Cluster 11

Synaptotagmin-1 molecules from the 0 mM Ca2+ Cluster 8

Synaptotagmin-1 molecules from the 0 mM Ca2+ Cluster 7

structure of a permease

structure of full permease

structure of a permease

Complex structure of a permease

structure of a permease

Complex structure of a permease

Cdc48-Ufd1-Npl4 complex processing Ub6 in the presence of ubx2

Cdc48-Ufd1-Npl4 complex processing polyUbEOS in the presence of ubx2

Focus refined map of ncBAF bound to nucleosome on the SnAC domain of SAMRCA4

Focus refined map of ncBAF bound to nucleosome on BRD9 grip helix

Cryo-EM structure of human UHRF1 bound to mononucleosome with hemimethylated DNA at superhelical location -6.2.

Structure of endogenous human ncBAF bound to nucleosome

Focus refined map of ncBAF bound to nucleosome on BCL7A

Cryo-EM structure of hemagglutinin from the A/California/04/2009 (H1N1) influenza virus with stabilizing mutations

Focus refinem map of ncBAF bound to nucleosome on the SMARCA4 motor domain

Focus refined map of ncBAf bound to nucleosome on the nucleosome

Structure of endogenous human ncBAF bound to nucleosome

Cryo-EM structure of hemagglutinin from the A/Malaysia/1706215/2007 (H1N1) influenza virus with stabilizing mutations

Cryo-EM structure of hemagglutinin from the A/swine/Hong Kong/2106/98 (H9N2) influenza virus with stabilizing mutations

Structure of a circMbl 48S translation initiation complex in the AUG recognition state

Cryo-EM Structure of the SCRIB-PP1 Complex

ARP module of ncBAF bound to numcleosome

Consensus EM map of ncBAF bound to nucleosome

Recombinant spore-silk A-ENA fibers

Structure of a circMbl 48S translation initiation complex in the scanning state

Recombinant spore-silk A-ENA-1 fibers

Cryo-EM structure of Vibrio cholerae divisome complex FtsWIQLB (periplasmic conformation 2)

Oxidized E.coli aerotaxis receptor in MH-cap bound state

Cryo-electron tomogram of Chroococcidiopsis thermalis PCC 7203 in white light

Cryo-EM structure of Vibrio cholerae divisome complex FtsWIQLB (periplasmic conformation 1)

Cryo-EM structure of Vibrio cholerae divisome complex FtsWIQLB (consensus)

Chimeric Hepatitis B Virus Core Antigen (HBc) Virus-like Particles (VLP) Incorporating SARS-CoV-2 Spike Protein Epitopes

SaPIbov1 Rep:dsDNA consensus

SaPIbov1 Rep:dsDNA component 2 frame 9

SaPIbov1 Rep:dsDNA component 1 frame 0

SaPIbov1 Rep:dsDNA component 0 frame 9

SaPIbov1 Rep:dsDNA component 1 frame 9

SaPIbov1 Rep:dsDNA component 0 frame 0

SaPIbov1 Rep:dsDNA component 2 frame 0

cryoEM map of dsDNA bound SaPIbov1 Rep helicase

Cryo-EM structure of Fluc-Nte in complex with cAMP-bound Fcap

Cryo-EM structure of Fluc-Nte in complex with ADP-bound Fcap

AHA hibernation factor bound to the 70S ribosome of Haloferax volcanii

Cryo-EM focused map of the active-state GPR55-N171Q mutant in complex with G13 and BI-6229

Inactive-state structure of GPR55 in complex with BI-6229

Structure of the Plant mitochondrial initiation complex, (SSU, LSU, initiator tRNA, mRNA)

Structure of the Plant mitochondrial pre-initiation complex 1, (SSU,mtIF3)

Cryo-EM focused map of inactive-state GPR55-bRIL-Fab-Nb bound to BI-8310

Cryo-EM consensus map of inactive-state GPR55-bRIL-Fab-Nb bound to BI-6229

Active-state structure of the GPR55-N171Q mutant in complex with G13 and BI-6229

Cryo-EM focused map of inactive-state GPR55-bRIL-Fab-Nb bound to BI-6229

Cryo-EM consensus map of inactive-state GPR55-bRIL-Fab-Nb bound to BI-8310

Inactive-state structure of GPR55 in complex with BI-8310

Cryo-EM consensus map of the active-state GPR55-N171Q mutant in complex with G13 and BI-6229

Structure of the Plant mitochondrial pre-initiation complex 3, (SSU,mtIF3,mRNA,tRNA)

Structure of the Plant mitochondrial pre-initiation complex 2, (SSU,mtIF3,mRNA)

Escherichia coli transhydrogenase double dIIIs detached to dIIs state in the presence of both NADPH and NADP+

CTP synthase dDON-condition state 1

CTP synthase dDON-condition state 2

Cryo-EM structure of SKF-83566 bound dopamine receptor DRD1-Gs signaling complex.

CTP synthase dDON-condition state 3

CTP synthase dDON-condition state 6

CTP synthase dDON-condition state 8

CTP synthase dDON-condition state 5

CTP synthase dDON-condition state 4

CTP synthase dDON-condition state 7

Type Ia alpha-synuclein filament amplified by One-Spin RT-QuIC from human plasma

Type Ib alpha-synuclein filament amplified by One-Spin RT-QuIC from human plasma

Type Ic alpha-synuclein filament amplified by One-Spin RT-QuIC from human plasma

Cryo-EM structure of Saccharomyces cerevisiae Mitochondrial Respiratory Complex II in YF241131B-bound state

Type IIb alpha-synuclein filament amplified by One-Spin RT-QuIC from human plasma

Type III alpha-synuclein filament amplified by One-Spin RT-QuIC from human plasma

Type I alpha-synuclein filament amplified from EV extraction buffer as a blank control for One-Spin RT-QuIC

Type A 2N4R human tau filaments induced by heparan sulfate with a double-protofilament fold

Type II alpha-synuclein filament amplified from EV extraction buffer as a blank control for One-Spin RT-QuIC

Type B 2N4R human tau filaments induced by heparan sulfate with a double-protofilament fold

Type B 2N4R human tau filaments induced by heparan sulfate with a single-protofilament fold

The cryo-EM structure of PBB3 bound type1 amyloid beta 42 fibril

The cryo-EM structure of F-BF227 bound type1 amyloid beta 42 fibril

The cryo-EM structure of ThS bound Tau PHF fibril

2N4R human tau filaments induced by heparin

The cryo-EM structure of Congored bound type1 amyloid beta 42 fibril

Alpha-synuclein filament amplified from preformed fibrils as a positive control for One-Spin RT-QuIC

The cryo-EM structure of ThS bound type1 amyloid beta 42 fibril

The cryo-EM structure of PiB bound type1 amyloid beta 42 fibril

First-generation 2N4R human tau filaments seeded by Alzheimer's disease tau

The cryo-EM structure of F-PI2620 bound type1 amyloid beta 42 fibril

Second-generation 2N4R human tau filaments seeded by Alzheimer's disease tau in the presence of heparan sulfate

The cryo-EM structure of F-FDDNP bound type1 amyloid beta 42 fibril

The cryo-EM structure of pFTAA bound type1 amyloid beta 43 fibril

SARS-CoV-2 Omicron LP.8.1 spike trimer (S-6P) in complex with 3 ZL58 Fabs and 3 ZL525 Fabs

factor VIIa-tissue factor-factor X-ixolaris complex in calcium ion-containing buffer

factor VIIa-tissue factor-factor X-ixolaris complex

Germline-like TCR156 bound to single-chain PAP-B2M-HLA-A*02

TCR AS4.2 bound to single-chain PRPF3-B2M-HLA-B*27:05

Germline-like TCR156 bound to single-chain NYESO-B2M-HLA-A*02

Germline-like TCR156 bound to single-chain MART1-B2M-HLA-A*02

Germline-like TCR A3A bound to single-chain MAGE-A3-B2M-HLA*A01

Germline-like TCR156 bound to single-chain poly-Ala-B2M-HLA-A*02

EBV gB trimer with "deD" mutations (intermediate-1 conformation)

EBV gB trimer with "delta" mutations (intermediate-2 conformation)

EBV gB trimer with "deli" mutations (postfusion conformation)

EBV gB trimer with "deliDoP" mutations and flexibly attached I5350A (prefusion-like conformation)

Germline-like A3A bound to single-chain Titin-B2M-HLA*A01

EBV gB trimer with "deliDoP" mutations and I5350A2h (prefusion conformation) - I5350A2h local refinement

VZV gB trimer with "deliD" mutations

EBV gB trimer with "deliDoP" mutations and I5350A2h (prefusion conformation) - DIII-DV local refinement

EBV gB trimer with "deliDoP" mutations and I5350A2h (prefusion conformation) - Global refinement

EBV gB trimer with "deliDoP" mutations and I5350A2hN (prefusion conformation) - I5350A2hN local refinement

EBV gB trimer with "deliDoP" mutations and I5350A2hN (prefusion conformation) - DI-DV local refinement

SARS-CoV-2 S 2P with C-terminal 4X oP3h motif (RINAIET) - local refinement

SARS-CoV-2 S 2P with C-terminal 4X oP3h motif (RINAIET)

SARS-CoV-2 S 2P with C-terminal 3X oP3h motif (RINEIER) - local refinement

SARS-CoV-2 S 2P with C-terminal 3X oP3h motif (RINEIER)

HSV1 gB dimer of prefusion-1 trimer and prefusion-2 trimer with "deliD" mutations

CMV gB trimer with "deliDoP" mutations and I5350A2hN (prefusion conformation)

Germline-like DMF5 bound to single-chain MART1-B2M-HLA-A*02

3A3 and 3A5 plus EBV gB trimer with "deliDoP" mutations and I5350A2hN (prefusion conformation) - 3A5 local refinement

EBV gB trimer with "deliDoP" mutations and I5350A2hN (prefusion conformation) - DII-DV local refinement

EBV gB trimer with "deliDoP" mutations and I5350A2h (prefusion conformation) - DII-DV local refinement

HSV1 gB prefusion-2 trimers with "deliD" mutations

3A3 and 3A5 plus EBV gB trimer with "deliDoP" mutations and I5350A2hN (prefusion conformation) - 3A3 local refinement

3D reconstruction of a cross section of the Indo-Pacific bottlenose dolphin sperm midpiece

Vibrio cholerae DnaB-DciA open ring complex

Trible-Gal ligand induced SBA nanotubules

Cryo-EM structure of hACE2 in complex with antibodies F9-12S and F9-64

YN-Gal ligand induced SBA nanotubules at 60 Celsius degree

Cryo-EM structure of hACE2 in complex with antibodies F9-26 and F9-8S

YNNN-Gal ligand induced SBA nanotubules at 4 Celsius degree

Cryo-EM structure of hACE2 in complex with NeoCoV RBD_MU3 and antibodies F9-63 and F9-64

V-Gal ligand induced SBA nanotubule

Double-Gal ligand induced SBA nanotubule 2

Cryo-EM structure of hACE2 in complex with antibodies F9-43 and F9-64

YN-Gal induced SBA nanotubules at 4 Celsius degree

Cryo-EM structure of hACE2 in complex with antibodies F9-3S and F9-21

Double-Gal ligand induced SBA nanotubule 1

Y-Gal ligand induced SBA nanotubules at 60 Celsius degree

Y-Gal ligand induced SBA nanotubule 2 at 37 Celsius degree

Y-Gal ligand induced SBA nanotubules

Y-Gal induced SBA nanotubule 1 at 37 Celsius degree

The cryo-EM structure of PBB3 bound Tau PHF fibril

insect ALKA channel

Y-Gal ligand induced SBA nanotubule 3 at 37 Celsius degree

Cryo-EM structure of deep sight fluorescence protein dsFP11

The cryo-EM structure of F-PI2620 bound Tau PHF fibril

Y-Gal ligand induced SBA nanotubules at 4 Celsius degree

The cryo-EM structure of CongoRed bound Tau PHF fibril

Bovine complex I at pH 9.2 in the deactive state (composite)

Bovine complex I at pH 9.2 in the deactive state (proximal membrane domain)

CryoEM structure of human 20S proteasome in complex with proteasome inhibitor Carmaphycin B

Structure of stacked allo-activated CBS conformer by allosteric SAM - by Helical approach

Compact Coxsackievirus B1 (CVB1) virus-like particle delta-PALXA

Bovine complex I at pH 6.0 in the deactive state (peripheral domain)

Bovine complex I at pH 6.0 in the slack state

Structure of trans-basal conformer of human CBS encompassing 16-18 dimer repeating units (in absence of substrate and allosteric ligand)- by Helical approach

Expanded Coxsackievirus B1 (CVB1) virus-like particle delta-PALXA

Bovine complex I at pH 6.0 in the deactive state (proximal membrane domain)

Bovine complex I at pH 9.2 in the deactive state (consensus)

Bovine complex I at pH 6.0 in the active state

Bovine complex I at pH 9.2 in the slack state

Bovine complex I at pH 6.0 in the deactive state (composite)

Bovine complex I at pH 6.0 in the deactive state (distal membrane domain)

Bovine complex I at pH 9.2 in the deactive state (peripheral domain)

Bovine complex I at pH 9.2 in the active state

Bovine complex I at pH 9.2 in the deactive state (distal membrane domain)

Bovine complex I at pH 6.0 in the deactive state (consensus)

CRYO-EM CONSENSUS MAP OF EKVX HUMAN CANCER CELL LINE RIBOSOME : CLASS 4

Ribosome of algae-fed tardigrade (R. varieornatus) - consensus map

Translating ribosome of algae-fed tardigrade (R. varieornatus) - eEF1A and tRNA (A/T-, P-, E-site) bound

Hibernating ribosome of rehydrated tardigrade (R. varieornatus) - eEF2, eIF5A, Cyp1 bound

Hibernating ribosome of algae-fed tardigrade (R. varieornatus) - eEF2, eIF5A bound

Membrane bound hibernating ribosome of unfed tardigrade (R. varieornatus) - eEF2, eIF5A, Cyp1 bound

Translating ribosome of unfed tardigrade (R. varieornatus) - eEF1A, tRNA (A/T-, P-, E-site) bound

Ribosome of unfed tardigrade (R. varieornatus) - unassigned state

Hibernating ribosome of unfed tardigrade (R. varieornatus) - eEF2, eIF5A bound - derived from classification with focused mask on membrane

Translating ribosome of unfed tardigrade (R. varieornatus) - tRNA (A-, P- site) bound

Hibernating ribosome of algae-fed tardigrade (R. varieornatus) - eEF2, eIF5A, Cyp1 bound

Ribosome of unfed tardigrade (R. varieornatus) - consensus map

Membrane bound ribosome of unfed tardigrade (R. varieornatus) - eEF1A, tRNA (A/T-, P-, E-site) bound

Hibernating ribosome of rehydrated tardigrade (R. varieornatus) - eEF2, eIF5A bound

Hibernating ribosome of unfed tardigrade (R. varieornatus) - eEF2, eIF5A bound - derived from classification with focused mask on A/P/E sites

Hibernating ribosome of rehydrated tardigrade (R. varieornatus) - eEF2 bound

Ribosome of unfed tardigrade (R. varieornatus) - ebp1, eEF2, eIF5A bound

Translating ribosome of algae-fed tardigrade (R. varieornatus) - tRNA (P-, E-site) bound

Translating ribosome of unfed tardigrade (R. varieornatus) - eEF1A, tRNA (A/T-, P-site) bound

Membrane bound ribosome of unfed tardigrade (R. varieornatus) - consensus map

Cryo-EM structure of unnatural-base aptamer AptD1c with DENV1 NS1 tetramer

Cryo-EM structure of H3K122ac nucleosome

Structure of recombinant RyR2 in complex with Ryanozole in the closed conformation (Ca2+ dataset)

Structure of recombinant RyR2 in complex with Ryanozole in the closed conformation (EGTA dataset)

Cryo-EM structure of unnatural-base aptamer AptD2 with DENV2 NS1

Translating ribosome of rehydrated tardigrade (R. varieornatus) - tRNA (A-, P-site) bound

Structure of recombinant RyR2 in the closed state (EGTA dataset)

Cryo-EM structure of the 198 bp human nucleosome containing H3.2 C110A mutant

Translating ribosome of rehydrated tardigrade (R. varieornatus) - eEF1A and tRNA (A/T-, P-, E-site) bound

Ribosome of rehydrated tardigrade (R. varieornatus) - consensus map

Structure of recombinant RyR2 in the open state (Ca2+ dataset)

Cryo-EM structure of unnatural-base aptamer AptD1 with DENV1 NS1 hexamer

Structure of recombinant RyR2 in complex with Ryanozole in the open conformation (Ca2+ dataset)

Translating ribosome of rehydrated tardigrade (R. varieornatus) - tRNA (P- , E-site) bound

Membrane bound translating ribosome of unfed tardigrade (R. varieornatus) - eEF1A, tRNA (A/T-, P-site) bound

Cryo-EM structure of the H3K56ac nucleosome

Cryo-EM structure of the H3K64ac nucleosome

Cryo-EM structure of GAPDH on a NHS-functionalized graphene grid

Structure of recombinant RyR2 in complex with Ryanozole in the closed conformation (EGTA dataset, Local refinement of Core domain)

Structure of recombinant RyR2 in the closed state (EGTA dataset, Local refinement of Core domain)

Cryo-EM structure of GAPDH on a silane-functionalized graphene grid

Structure of recombinant RyR2 in complex with Ryanozole in the closed conformation (Ca2+ dataset, Local refinement of Core domain)

Cryo-EM structure of GAPDH on a functionalized graphene grid

Structure of recombinant RyR2 in the open state (Ca2+ dataset, Local refinement of Core domain)

Yeast mitochondrial TOM complex

Structure of recombinant RyR2 in complex with Ryanozole in the open conformation (Ca2+ dataset, Local refinement of Core domain)

HBV capsid in complex with Matrix Domain of HBsAg PreS

HBV capsid (T=4)

Cryo-EM map of the 70S ribosome from stationary-phase Methanolobus in complex with P/E-tRNA

Cryo-EM map of the native ARC-bound 70S ribosome from stationary-phase Methanolobus

Cryo-EM map of the 70S ribosome from oxygen-stressed Methanolobus in complex with A/P-tRNA and P/E-tRNA

Cryo-EM map of the 70S ribosome from oxygen-stressed Methanolobus

Cryo-EM map of the 70S ribosome from oxygen-stressed Methanolobus in complex with P/P-tRNA

Cryo-EM map of the native ARC-bound 70S ribosome from oxygen-stressed Methanolobus

Cryo-EM map of the 50S ribosomal subunit from stationary-phase Methanolobus

Cryo-EM map of the 70S ribosome from oxygen-stressed Methanolobus in complex with P/E-tRNA

smKCS-smCER2 in complex with C22-CoA

smKCS-smCER2 complex in Apo state

Cryo-EM map of the 50S ribosomal subunit from oxygen-stressed Methanolobus

smKCS6-smCER2 complex carrying the V434N mutation in smKCS6

smKCS-smCER2 in complex with MCoA

smKCS-smCER2 in complex with C22-CoA and MCoA

Single protofilament with the Alzheimer tau fold and the V337M mutation from seeded primary murine neurons

Paired helical filament from Alzheimer's disease brain (AD seed)

DNA-bound POLQTaqChimera in complex with compound 41

Paired helical filament with the V337M mutation from seeded primary murine neurons

Structure of the ATPalphaS-bound soluble domain of human Adenylyl cyclase 9 in complex with stimulatory G protein, ATPalphaS, and forskolin

Cryo-EM structure of the RESC1-RESC2 complex bound to KREH2

Structure of the occluded-state soluble domain of human Adenylyl cyclase 9 in complex with stimulatory G protein, ATPalphaS, and forskolin

Cryo-EM structure of full-length plasminogen variant R561A

Structure of the soluble domain of chimeric Adenylyl cyclase 95 in complex with stimulatory G protein, ATPalphaS, and forskolin

Cryo-EM Structure of Dimer-of-Dimers EcCaspase Bound to N7-cADPR

Cryo-EM Structure of Dimeric EcCaspase Filament in Apo State

Cryo-EM Structure of Tetrameric EcCaspase Filament in Apo State

Cryo-EM Structure of Dimer-of-Dimers EcCaspase in Apo State

Cryo-EM Structure of Tetrameric EcCaspase Filament Bound to N7-cADPR

HIV-1 CA hexamer-hexamer interface from purified viral cores (consensus)

HIV-1 CA hexamer-hexamer interface from purified viral cores tilt 23.0 twist -4.7

HIV-1 CA hexamer-hexamer interface from purified viral cores tilt 16.6 twist -1.5

HIV-1 CA hexamer-hexamer interface from purified viral cores tilt 9.8 twist 1.9

HIV-1 CA hexamer-hexamer interface from purified viral cores tilt 21.1 twist 4.1

Structure of E04 Fab in complex with B/Lee40/1940 influenza B virus hemagglutinin

HIV-1 CA hexamer-hexamer interface from purified viral cores tilt 17.4 twist -2.1

Hypomethylated nucleoplasmic pre-60S intermediate containing Nog2 at Rsa4-arrested 5S post-rotation state

Closed state of D-ornithine 4,5-aminomutase from Fervidobacterium nodosum

Open state of D-ornithine 4,5-aminomutase from Fervidobacterium nodosum

48S closed head conformation

5MP (eIF1S) 43-like complex *only eIF3c subunit

Cryo-EM structure of human Fibroblast Activation Protein alpha in complex with H4 VNAR

Cryo-EM structure of human Fibroblast Activation Protein alpha in complex with F7 VHH

Cryo-EM structure of human Fibroblast Activation Protein alpha in complex with huB12 IgG

Lepidopteran Chorion Central Domain Amyloid Fibril Polymorph 4

Candida albicans ribosome in the hibernating state reconstructed using 2D template matching from in-situ micrographs

Amino-terminal domain for GluK2 in the apo state with asymmetric ligand binding domain

Ligand-binding and transmembrane domains for GluK2 in the apo state with asymmetric ligand binding domain

Amino-terminal domain for GluK2 in the apo state with 2-fold symmetrical ligand-binding domain

Ligand-binding and transmembrane domains for GluK2 in the apo state with 2-fold symmetrical ligand binding domain

Cryo-EM focus refinement of UL8 subunit of UL5/UL8/UL52 complex

Consensus map for GluK2 in the apo state with 2-fold symmetrical ligand-binding domain

structure of SARS-CoV-2 BA.2 S protein, closed

Consensus map for GluK2 in the apo state with asymmetric ligand binding domain

SSU processome maturation and disassembly, State A - Bfr2Kre33 focused map

Structure of aptamer in complex with SARS-CoV-2 BA.2 S protein, open

Cryo-EM structure of UL5/UL8/UL52 from Herpes Simplex Virus 1 in the presence of ATP-gamma-S

Cryo-EM focus refinement of UL5 and UL52 subunits of UL5/UL8/UL52 complex

Structure of SARS-CoV-2 BA.2 S Protein, closed

Cryo-EM structure of UL5/UL52 heterodimer from Herpes Simplex Virus 1 in complex with Pritelivir and ssDNA

Cryo-EM structure of UL52 catalytic core in complex with UL8 subunit from Herpes Simplex Virus 1

Cryo-EM structure of the CIII2 with YlbA from Bacillus subtilis

Pyrin CTD volume in the Pyrin inhibited complex

Pyrin PYD filament

14-3-3 heterodimer bound to phosphorylated Pyrin linkers

14-3-3E homodimer in the Pyrin inhibited complex

Bacteroides SusCD + Maltoheptaose - Closed w/ Plug Domain

Arabidopsis H2AXa containing nucleosome, Canonical

Bacteroides SusCD Unliganded - Closed w/ Plug Domain

Bacteroides SusCD Unliganded - Closed w/o Plug

SusCD Wide Open from Bacteroides thetaiotaomicron

Bacteroides SusCD Unliganded - Open w/ Plug

VAR2CSA in complex with V2C.014 Fab

VAR2CSA in complex with V2C.044 Fab

VAR2CSA in complex with V2C.015 Fab

VAR2CSA in complex with V2C.041 Fab

Subtomogram Averaged Cryo-ET Structure of the 96-nm Axonemal Repeat in RSP3B-KO Tetrahymena thermophila