The Electron Microscopy Data Bank (EMDB) is a public repository for cryogenic-sample Electron Microscopy (cryoEM) volumes and representative tomograms of macromolecular complexes and subcellular structures. It covers a variety of techniques, including single-particle analysis, helical reconstruction, electron tomography, subtomogram averaging, and electron crystallography. More...
As of 11 June 2025, EMDB contains 46560 entries (latest entries, trends).
EMDB News
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06 January 2024: We are delighted to share that EMDB has officially been elevated to a Core Data Resource by ELIXIR, recognising it as a European data resource of fundamental importance to the wider life-science community and the long-term preservation of biological data.
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22 November 2023: We are happy to share the most recent version of the EMDB Nucleic Acids Research paper. The paper describes recent developments and future plans of the EMDB in the context of the worldwide Protein Data Bank. Check it out now! https://doi.org/10.1093/nar/gkad1019
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Structure of Alpha-hemolysin heptameric pore state derived from Egg-PC/SM liposomes.
Alpha-hemolysin heptameric pre-pore state derived from 10:0 PC liposomes.
Structure of the auxin importer AUX1 in Arabidopsis thaliana in the IAA-bound state
SARS-CoV-2 Replication-Transcription Complex has a dimer-of-dimeric architecture (ddRTC) in pre-capping initiation.
RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome containing histone variant H2A.B
Cryo-EM structure of CasLambda2-crRNA-target DNA ternary complex in the incompetent state
Cryo-EM structure of CasLambda2-crRNA-target DNA ternary complex in the TS-cleaving state
Alpha-hemolysin heptameric late pre-pore state derived from 10:0 PC/Sphingomyelin liposomes
Cryo-EM structure of CasLambda2-crRNA-target DNA ternary complex in the NTS-cleaving state
RNA polymerase II elongation complex stalled at SHL(-5) of the nucleosome containing histone variant H2A.B
Consensus map of Cx43/GJA1 gap junction channel in the presence of diC8-PIP2 (16-fold molar excess)
Cryo-EM Density map of Staphylococcus aureus alpha-hemolysin pore structure derived from 12:0 Phosphatidylcholine (12:0 PC) liposome
Structure of Cx43/GJA1 gap junction intercellular channel in complex with diC8-PIP2
Cryo-EM structure of CasLambda2-crRNA-target DNA ternary complex in the intermediate state
Alpha-hemolysin heptameric pore state derived from 10:0 PC liposomes
Cryo-EM structure of the histamine H4 receptor-Gi protein complex (Overall)
Cryo-EM structure of the histamine H4 receptor-Gi protein complex (Receptor focused)
Structure of calcium preference ATP-gated channel P2X1 in the Desensitized state 4 in the presence of 10mM Calcium ion
Structure of calcium preference ATP-gated channel Apo-P2X1 in the Desensitized state 1
Structure of calcium preference ATP-gated channel P2X1 in the Desensitized state 3 in the presence of 5mM Calcium ion
Cryo-EM structure of ATP-bound P2Y purinoceptor 2-miniGq-Nb35 complex
Cryo-EM structure of Cas12X with crRNA and Target DNA, Conformation 3
Structure of calcium preference ATP-gated channel P2X1 in the Desensitized state 2 in the presence of 1mM Calcium ion
Cryo-EM structure of UTP-bound P2Y purinoceptor 4-miniGq-Nb35 complex
Structure of calcium preference ATP-gated channel P2X1 in the Pre-open state in the presence of 10mM Calcium ion
Structure of calcium preference ATP-gated channel P2X1 in the Desensitized state 5 in the presence of 10 mM Calcium ion
Cryo-EM structure of ATP-bound P2Y purinoceptor 2-miniGo-scFv16 complex
sStructure of calcium preference ATP-gated channel P2X1 in complex with BTFA
Cryo-EM structure of Cas12X with crRNA and Target DNA, Conformation 1
Cryo-EM structure of the inward-open choline-bound state of choline/ethanolamine transporter FLVCR2
Cryo-EM Structure of Amyloid-beta Fibrils Carrying the Uppsala AbetaUpp(1-42)delta(19-24) Mutation - Polymorph 3
Consensus map of the 70S ribosome of a MLSb sensitive S. aureus strain "KES34" in complex with solithromycin
Cryo-EM structure of the beta3 homomeric GABA(A) receptor in complex with HSM in the short-lived asymmetric open state
Cryo-EM Structure of Amyloid-beta Fibrils Carrying the Uppsala AbetaUpp(1-42)delta(19-24) Mutation - Polymorph 2
Structure of 30S ribosomes determined by cryoEM prepared with foam film vitrification method
Cryo-EM structure of the alpha1beta3gamma2 GABA(A) receptor in complex with GABA and Nb38 in the short-lived asymmetric open 2 state
Cryo-EM structure of the large subunit of the mitochondrial ribosome from Toxoplasma gondii
Cryo-EM structure of Lysozyme homo-dimer assembled by homo Di-Gluebody - Local refinement
Cryo-EM Structure of Amyloid-beta Fibrils Carrying the Uppsala AbetaUpp(1-42)delta(19-24) Mutation - Polymorph 1
Perkinsus marinus Respiratory supercomplex CII2CIII2 map in an intermediate state
Structure of paired helical filament determined by cryoEM prepared with foam film vitrification method
Structure of catalase determined by cryoEM prepared with foam film vitrification method
Postprocessed map of the focused refinement of the small ribosomal subunit body of a MLSb sensitive S. aureus strain "KES34"
Postprocessed map of the focused refinement of the small ribosomal subunit head of the MLSb sensitive S. aureus strain "KES34"
Structure of EspB 14-mers determined by cryoEM prepared with foam film vitrification method
Structure of 20S proteasomes determined by cryoEM prepared with foam film vitrification method
Subtomogram average of three fascins in complex with two actin filaments
Structure of AcrB determined by cryoEM prepared with foam film vitrification method
Cryo-EM Structure of Amyloid-beta Fibrils from Mouse Brain Carrying the Uppsala AbetaUpp(1-42)delta(19-24) Mutation
Structure of the Sabia Virus spike complex in a closed conformation
Single particle cryo-EM reconstruction of Bacillus Methanolicus encapsulin nano compartment
Mouse mitoribosome large subunit assembly intermediate (with uL16m) bound to MRM3-dimer, DDX28 and the MALSU-L0R8F8-mt-ACP complex, state A2 (SAMC knock-out)
Cryo-EM structure of the small subunit of the mitochondrial ribosome from Toxoplasma gondii
Cryo-EM Structure of Tau Filaments from Individuals Carrying the Uppsala AbetaUpp(1-42)delta(19-24) Mutation
Cryo-EM Structure of Amyloid-beta Fibrils from Individual Carrying the Uppsala AbetaUpp(1-42)delta(19-24) mutation
Structure of the Sabia Virus spike complex in a closed conformation
Structure of EspB determined by cryoEM prepared with foam film vitrification
Focused refinement of the large ribosomal subunit of a MLSb sensitive S. aureus strain "KES34" in complex with solithromycin
Structure of the Sabia Virus spike complex H157M mutant in a closed conformation
Cryo-EM Structure of Amyloid-beta Fibrils Carrying the Uppsala AbetaUpp(1-42)delta(19-24) Mutation - Polymorph 4
Cryo-EM structure of Lysozyme homo-dimer assembled by homo Di-Gluebody
Structure of the outer membrane exopolysaccharide transporter PelBC
2.54 A S.cerevisiae Chd1[L886G/L889G/L891G]-nucleosome 1:1 complex
SARS-CoV-2 nsp1 bound to the Rhinolophus lepidus 40S ribosomal subunit (local refinement of the 40S body)
Cryo-EM map of the human UBR4-KCMF1-CaM E3 Ligase complex (Silencing Factor of the Integrated stress response, SiFI) N-terminal region
Clone 2.1 Fab in complex with chicken IgY CH2 domain (local refinement)
Structure of native murine cardiac thin filament at pCa=5.8 in Ca2+-bound fully activated state (upper strand)
Rhesus Fab 42056-a.01 in complex with CAP256SU.wk34 RnS SOSIP Env
Cryo-EM structure of SINV/EEEV in complex with a potently neutralizing human antibody IgG EEEV-373
Structure of native murine cardiac thin filament at pCa=5.8 in Ca2+-bound partially activated state (upper strand)
SaPI1 neck structure with DNA, tail completion protein, and tape measure protein
Rhesus Fab 6561-a.01 in complex with HIV-1 Ce1176.A3 RnS SOSIP Env
2.88 A S.cerevisiae Chd1[L886G/L889G/L891G]-nucleosome 2:1 complex with DNA-binding domain
Cryo-electron tomography of plasma membranes generated from caspofungin-treated Candida glabrata spheroplasts
Cryo-EM structure of glucagon-like peptide-1 receptor (GLP-1R)-Gs complex with Exendin-phe1
Cryo-EM structure of glucagon-like peptide-1 receptor (GLP-1R)-Gs complex with Exendin-asp3
Herpes simplex virus type 1 (HSV-1) A-capsid pUL6 portal protein, dodecameric complex
Structure of native murine cardiac thin filament at pCa=5.8 in Ca2+-free rotated state (upper strand)
2.37 A S.cerevisiae Chd1[L886G/L889G/L891G]-nucleosome reconstructruction. Combined 1:1 and 2:1 complexes
Single subunit of Epstein-Barr virus annealase BALF2 ssDNA-annealing complex
Filamentous Epstein-Barr virus annealase BALF2 ssDNA-annealing complex
Structure of native murine cardiac thin filament variant I79N in troponin T at pCa=5.8 in Ca2+-free state (lower strand)
2.61 A S.cerevisiae Chd1[L886G/L889G/L891G]-nucleosome 2:1 complex
SARS-CoV-2 nsp1 bound to the Rhinolophus lepidus 40S ribosome (local refinement of the 40S head)
Two-subunit asymmetric unit of Epstein-Barr virus annealase BALF2 ssDNA-annealing complex
2.90 A S.cerevisiae Chd1[L886G/L889G/L891G]-nucleosome 2:1 complex with C-terminal activator helix around residue 945
Structure of human UBR4-KCMF1-CaM E3 ligase complex (Silencing Factor of the Integrated stress response, SiFI)
Cryo-EM structure of SINV/EEEV in complex with a potently neutralizing intact human antibody EEEV-373
SARS-CoV-2 nsp1 bound to the Rhinolophus lepidus 40S ribosome (consensus map)
Structure of native murine cardiac thin filament at pCa=5.8 in Ca2+-free tilted state (upper strand)
Consensus reconstruction of the eukaryotic Ribosome-associated Quality Control complex
Alpha-hemolysin heptameric pore state derived from egg PC/Cholesterol (3:1 molar ratio) liposomes
Consensus map of Cx43/GJA1 gap junction channel in the presence of diC8-PIP2 (8-fold molar excess)