EMDB (the Electron Microscopy Data Bank) is a public repository for electron cryo-microscopy maps and tomograms of macromolecular complexes and subcellular structures. It covers a variety of techniques, including single-particle analysis, electron tomography, sub-tomogram averaging, fibre diffraction and electron crystallography. More...
As of 25 January 2023, EMDB contains 24656 entries (latest entries, trends).
EMDB News
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21 December 2022: EMDB proudly announces the EMICSS resource. It provides weekly updated cross-reference information for all EMDB entries to other resources (including PDB, EMPIAR, Europe PMC, UniProt, AlphaFold DB and many more.) Read more here: emdb-empiar.org/emicss.
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12 October 2022: EMDB Validation Analysis (VA) is officially launched at https://www.ebi.ac.uk/emdb/va/. It is available as a local stand-alone package and is coming soon to CCP-EM. The tutorial on how to use the VA information is on EMDB YouTube channel. A full description of VA functionality is published in Acta Crystallographica Section D.
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(Show all)Structure of 30S ribosomal subunit at 2.5 mM Magnesium concentration
Negative stain EM map of SARS-CoV-2 Spike in complex with CoVIC-290
Cryo-EM structure of SARS-CoV-2 Omicron BA.2 spike protein in complex with Fab 4A8 (focused refinement of NTD and 4A8)
Cryo-EM structure of the Cyanobium sp. PCC 7001 Carboxysome internal density middle layer
Negative stain EM map of SARS-CoV-2 Spike in complex with CoVIC-355
SARS-CoV-2 Omicron BA.1 spike trimer (6P) in complex with 3 YB13-292 Fabs (3 RBD down)
Cryo-EM structure of ACh-bound M2R-Go signaling complex in S1 state
E. coli ATP synthase imaged in 10mM MgATP State 1 "down" Fo classified
Negative stain EM map of SARS-CoV-2 Spike in complex with CoVIC-279
TMEM106B singlet filament extracted from MSTD neurodegenerative human brain
80S human ribosome structure from PFIB lamellae of HeLa cells for assessing the extend and depth of the damage layer: above 60 nm matched control (for 45 to 60 nm)
Negative stain EM map of SARS-CoV-2 Spike in complex with CoVIC-333
Negative stain EM map of SARS-CoV-2 Spike in complex with CoVIC-334
Cryo-EM structure of Mycobacterium tuberculosis irtAB complexed with ATP in an occluded conformation
Hemichannel-focused structure of C-terminal truncated connexin43/Cx43/GJA1 gap junction intercellular channel in POPE nanodiscs (GCN-TM1i conformation)
Negative stain EM map of SARS-CoV-2 Spike in complex with CoVIC-368
E. coli ATP synthase epsilon helix1 deletion mutant imaged in 10mM MgATP State1
Maedi visna virus Vif in complex with CypA and E3 ubiquitin ligase
E. coli ATP synthase imaged in 10mM MgATP State1 "half-up" Fo classified
Cryo-EM structure of Human Enterovirus D68 US/MO/14-18947 strain native virion
Hemichannel-focused structure of C-terminal truncated connexin43/Cx43/GJA1 gap junction intercellular channel in POPE nanodiscs (GCN conformation)
SARS-CoV-2 Omicron BA.1 spike trimer (6P) in complex with 3 YB13-292 Fabs (2 RBD up)
Cryo-EM structure of Human Enterovirus D68 US/MO/14-18947 strain virion in complex with inhibitor 11526092
Negative stain EM map of SARS-CoV-2 Spike in complex with CoVIC-360
Cryo-EM structure of catalytically active Spinacia oleracea cytochrome b6f in complex with endogenous plastoquinones at 2.13 A resolution
Hemichannel-focused structure of C-terminal truncated connexin43/Cx43/GJA1 gap junction intercellular channel in POPE nanodiscs (FIN conformation)
SARS-CoV-2 Omicron BA.1 spike trimer (6P) in complex with 1 YB9-258 Fab (1 RBD up)
Cryo-EM structure of methane monooxygenase hydroxylase (by quantifoil)
CryoEM structure of human alpha-synuclein A53T fibril induced by calcium ions
Cryo-EM structure of S1 state ACh-bound M2R-Go signaling complex with a PAM
80S human ribosome structure from PFIB lamellae of HeLa cells for assessing the extend and depth of the damage layer: 0 to 15 nm
Design of Diverse Asymmetric Pockets in de novo Homo-oligomeric Proteins
Negative stain EM map of SARS-CoV-2 Spike in complex with CoVIC-292
Cryo-EM structure of Human Enterovirus D68 US/MO/14-18947 strain in complex with inhibitor 11526091 (no/low occupancy-no inhibitor modeled)
Cryo-EM structure of Mycobacterium tuberculosis irtAB in complex with an AMP-PNP
Structure of connexin43/Cx43/GJA1 gap junction intercellular channel in GDN detergents at pH ~8.0
Cryo-EM structure of methane monooxygenase hydroxylase (by graphene)
SARS-CoV-2 Omicron BA.1 spike trimer (6P) in complex with YB9-258 Fab, focused refinement of Fab region
Negative stain EM map of SARS-CoV-2 Spike in complex with CoVIC-299
SARS-CoV-2 wildtype spike trimer (6P) in complex with 3 YB9-258 Fabs and 3 R1-32 Fabs (3 RBD up)
Cryo-EM structure of SARS-CoV-2 Omicron BA.2 spike protein in complex with Fab 4A8
Structure of the Inmazeb cocktail and resistance to escape against Ebola virus
80S human ribosome structure from PFIB lamellae of HeLa cells for assessing the extend and depth of the damage layer: above 45 nm matched control (for 30 to 45 nm)
Cryo-EM structure of the Cyanobium sp. PCC 7001 Carboxysome internal density outer layer
Cryo-EM structure of Human Enterovirus D68 US/MO/14-18947 strain in complex with inhibitor 11526093 (no/low occupancy-no inhibitor modeled)
Cryo-EM structure of S2 state ACh-bound M2R-Go signaling complex with a PAM
SARS-CoV-2 Omicron BA.1 spike trimer (6P) in complex with 2 YB9-258 Fabs (2 RBD up)
human MutSalpha (MSH2/MSH6) on DNA containing a GT mismatch in the presence of ADP
CryoEM structure of an anti-CRISPR protein AcrIIC5 bound to Nme1Cas9-sgRNA complex
microtubule decorated with tubulin oligomers in presence of APC C-terminal domain. (here only the microtubule map section is represented)
Cryo-electron microscopy of Adeno-associated virus serotype 4 at 2.2 A
80S human ribosome structure from PFIB lamellae of HeLa cells for assessing the extend and depth of the damage layer: above 15 nm matched control (for 0 to 15 nm)
Structure of interleukin receptor common gamma chain (IL2Rgamma) in complex with two antibodies
Cryo-EM structure of human ferroportin/slc40 bound to Ca2+ in nanodisc
SARS-CoV-2 Omicron BA.1 spike trimer (6P) in complex with YB13-292 Fab, focused refinement of Fab region
E. coli ATP synthase imaged in 10mM MgATP State2 "half-up" Fo classified
Negative stain EM map of SARS-CoV-2 Spike in complex with CoVIC-295
80S human ribosome structure from PFIB lamellae of HeLa cells for assessing the extend and depth of the damage layer: 15 to 30 nm
Cryo-EM structure of the E.coli 70S ribosome in complex with the antibiotic Myxovalargin B.
microtubule decorated with tubulin oligomers in presence of APC C-terminal domain. (here only map corresponding to the external tubulin oligomer is represented)
Cryo-EM structure of ACh-bound M2R-Go signaling complex in S2 state
Cryo-EM structure of tetrameric TLR3 in complex with dsRNA (90 bp)
Cryo-EM structure of Human Enterovirus D68 US/MO/14-18947 strain virion in complex with pleconaril
human MutSalpha mutant (MSH2-V63E/MSH6) on DNA containing a GT mismatch
1 sulfate and 1 ATP bound V1EG of V/A-ATPase from Thermus thermophilus.
80S human ribosome structure from PFIB lamellae of HeLa cells for assessing the extend and depth of the damage layer:30 to 45 nm
E. coli ATP synthase epsilon helix1 deletion mutant imaged in 10mM MgATP State3
Consensus map of connexin43/Cx43/GJA1 gap junction intercellular channel in LMNG/CHS detergents at pH ~6.9
Cryo-EM structure of Mycobacterium tuberculosis irtAB in complex with ADP
Negative stain EM map of SARS-CoV-2 Spike in complex with CoVIC-361
SARS-CoV-2 Omicron BA.1 spike trimer (6P) complex with YB9-258 Fab, focused refinement of RBD-dimer region
Cryo-EM structure of Mycobacterium tuberculosis irtAB in inward-facing state
E. coli ATP synthase imaged in 10mM MgATP State3 "down" Fo refine
Cryo-EM structure of the Arabidopsis thaliana I+III2 supercomplex (Complete composition)
Negative stain EM map of SARS-CoV-2 Spike in complex with CoVIC-294
E. coli ATP synthase imaged in 10mM MgATP State3 "down" Fo classified
E. coli ATP synthase imaged in 10mM MgATP State2 "down" Fo refine
E. coli ATP synthase imaged in 10mM MgATP State2 "half-up" Fo refine
Cryo-EM structure of SARS-CoV-2 Omicron BA.2 spike protein (focused refinement of NTD)
Structure and mechanism of a mitochondrial AAA+ disaggregase CLPB
Cryo-EM structure of catalytically active Spinacia oleracea cytochrome b6f in complex with endogenous plastoquinones at 2.7 A resolution
E. coli ATP synthase epsilon helix1 deletion mutant imaged in 10mM MgATP State2
Negative stain EM map of SARS-CoV-2 Spike in complex with CoVIC-371
Cryo-EM structure of an a-carboxysome RuBisCO enzyme at 2.9 A resolution
E. coli ATP synthase imaged in 10mM MgATP State 1 "half-up" Fo refine
80S human ribosome structure from PFIB lamellae of HeLa cells for assessing the extend and depth of the damage layer:45 to 60 nm
80S human ribosome structure from PFIB lamellae of HeLa cells for assessing the extend and depth of the damage layer: above 30 nm matched control (for 15 to 30 nm)
Negative stain EM map of SARS-CoV-2 Spike in complex with CoVIC-362
Cryo-EM structure of one baculovirus LEF-3 molecule in complex with ssDNA
Negative stain EM map of SARS-CoV-2 Spike in complex with CoVIC-260
H10ssF: ferritin-based nanoparticle displaying H10 hemagglutinin stabilized stem epitopes
E. coli ATP synthase imaged in 10mM MgATP State2 "down" Fo classified
Cryo-EM structure of a delivery complex containing the SspB adaptor, an ssrA-tagged substrate, and the AAA+ ClpXP protease
SARS-CoV-2 Omicron BA.1 spike trimer (6P) in complex with 3 YB13-292 Fabs (1 RBD up)
Negative stain EM map of SARS-CoV-2 Spike in complex with CoVIC-234
Hemichannel-focused structure of C-terminal truncated connexin43/Cx43/GJA1 gap junction intercellular channel in POPE nanodiscs (PLN conformation)