EMD-64592

Single-particle
3.14 Å
EMD-64592
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Deposition: 14/05/2025
Map released: 27/05/2026
Last modified: 27/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-64592
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The binding of a C-based single-domain antibody stabilizes spikes of SARS-CoV2 (JN.1) in all-RBD-up conformation

EMD-64592

Single-particle
3.14 Å
EMD-64592
3D View Gallery
Deposition: 14/05/2025
Map released: 27/05/2026
Last modified: 27/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Severe acute respiratory syndrome coronavirus 2, Homo sapiens
Sample: The complex formed by SARS-CoV2 JN.1 spike protein and a single-domain antibody

Deposition Authors: Wu B, Rao G, Cao S, Gong R

A C-based single-domain antibody broadly neutralizes SARS-CoV-2 and its variants through novel recognition of conserved regions in RBD
Wu B, Rao G, Zhang H, Yi Y, Zhao S, Qin Y, Li M, Chen L, Zhang Z, Zhang Z, Mu J, Chiu S, Cao S, Gong R
To Be Published