EMD-53329

Single-particle
3.3 Å
EMD-53329
3D View Gallery
Deposition: 04/04/2025
Map released: 27/05/2026
Last modified: 27/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-53329
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9qs6 summary report (pdf.gz) Map and 9qs6 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of the helix-stabilized MMM ubiquitin ligase complex with nanobody 270 (Composite map)

EMD-53329

Single-particle
3.3 Å
EMD-53329
3D View Gallery
Deposition: 04/04/2025
Map released: 27/05/2026
Last modified: 27/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Lama glama
Sample: Helix-stabilized human MEGF8-MOSMO-MGRN1 (MMM) ternary complex bound to nanobody 270
Fitted models: 9qs6

Deposition Authors: Williams C, Carrique L, Pardon E, Nocka LM, Hedger G, Pusapati GV, Parashara P, Latorraca NR, Sarkar P, Lartey D, Gao L, Milenkovic L, Steyaert J, Bazan F, Rouse S, Marqusee S, Kong JH, Rohatgi R, Siebold C
Design principles of a membrane-spanning ubiquitin ligase
Williams C, Nocka LM, Hedger G, Carrique L, Pusapati GV, Parashara P, Latorraca NR, Sarkar P, Lartey D, Gao L, Pardon E, Milenkovic L, Steyaert J, Bazan F, Rouse S, Marqusee S, Kong JH, Siebold C, Rohatgi R
(2026) Mol Cell
DOI: doi:10.1016/j.molcel.2026.05.001
ISSN: 1097-2765
ASTM: MOCEFL
Grant Support: