EMD-57249

Single-particle
2.95 Å
EMD-57249
3D View Gallery
Deposition: 19/03/2026
Map released: 27/05/2026
Last modified: 27/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-57249
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Focused refinement of the helix-stabilized MEGF8-MOSMO complex with nanobody 270

EMD-57249

Single-particle
2.95 Å
EMD-57249
3D View Gallery
Deposition: 19/03/2026
Map released: 27/05/2026
Last modified: 27/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Lama glama
Sample: Helix-stabilized human MEGF8-MOSMO binary complex bound to nanobody 270

Deposition Authors: Williams C, Carrique L, Pardon E, Nocka LM, Hedger G, Pusapati GV, Parashara P, Latorraca NR, Sarkar P, Lartey D, Gao L, Milenkovic L, Chalk R, Steyaert J, Bazan F, Rouse SL, Marqusee S, Kong JH, Rohatgi R, Siebold C
Design principles of a membrane-spanning ubiquitin ligase
Williams C, Nocka LM, Hedger G, Carrique L, Pusapati GV, Parashara P, Latorraca NR, Sarkar P, Lartey D, Gao L, Pardon E, Milenkovic L, Chalk R, Steyaert J, Bazan F, Rouse SL, Marqusee S, Kong JH, Siebold C, Rohatgi R
(2026) Mol Cell
DOI: doi:10.1016/j.molcel.2026.05.001
ISSN: 1097-2765
ASTM: MOCEFL
Grant Support: