EMD-53340

Single-particle
3.5 Å
EMD-53340
3D View Gallery
Deposition: 04/04/2025
Map released: 27/05/2026
Last modified: 27/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-53340
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9qsh summary report (pdf.gz) Map and 9qsh FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of the MMM ubiquitin ligase complex with nanobody 992 (Composite map)

EMD-53340

Single-particle
3.5 Å
EMD-53340
3D View Gallery
Deposition: 04/04/2025
Map released: 27/05/2026
Last modified: 27/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Lama glama
Sample: Human MEGF8-MOSMO-MGRN1 (MMM) ternary complex bound to nanobody 992
Fitted models: 9qsh

Deposition Authors: Williams C, Carrique L, Pardon E, Nocka LM, Hedger G, Pusapati GV, Parashara P, Sarkar P, Latorraca NR, Lartey D, Gao L, Milenkovic L, Steyaert J, Bazan F, Rouse SL, Marqusee S, Kong JH, Rohatgi R, Siebold C
Design principles of a membrane-spanning ubiquitin ligase
Williams C, Nocka LM, Hedger G, Carrique L, Pusapati GV, Parashara P, Latorraca NR, Sarkar P, Lartey D, Gao L, Pardon E, Milenkovic L, Steyaert J, Bazan F, Rouse SL, Marqusee S, Kong JH, Siebold C, Rohatgi R
(2026) Mol Cell
DOI: doi:10.1016/j.molcel.2026.05.001
ISSN: 1097-2765
ASTM: MOCEFL
Grant Support: