EMD-76979

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EMD-76979
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Deposition: 30/04/2026
Map released: 27/05/2026
Last modified: 27/05/2026
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EMD-76979
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Cryo-ET of mitochondrial membrane in direct interaction with alpha-synuclein exhibiting membrane morphological distortion

EMD-76979

Tomography
EMD-76979
Gallery
Deposition: 30/04/2026
Map released: 27/05/2026
Last modified: 27/05/2026
Overview Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Cell lysate from 3k M17D neuroblastoma cell line

Deposition Authors: Jaber N , Dai W

Lipid droplets promote the aberrant liquid-liquid phase separation of alpha-synuclein leading to impaired energy homeostasis
Cevallos J, Eubanks E, Jung S, Huang Y, Guadagno E, Jaber N , Xia Y, Wang J, Wang H, Suvvari NR, Doshi A, Ravinutala N, Mosera A, Hsu T, Mody J, Sacks B, Narayan A, Smith B, Wang M, Gottapu M, Ramalingam N, Tripathi A, Bartels T, Dettmer U, Shi Z, Dai W , Kara E
To Be Published