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Substrates for peptidase M12.210: ADAM10 peptidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
26S protease regulatory subunit 7 (26S proteasome AAA-ATPase subunit RPT1) (Proteasome 26S subunit ATPase 2) (Protein MSS1) P46471 1-433 peptide-Leu32+Leu-peptide N MS Asp Ile Ala Leu Leu Lys Thr Tyr Scharfenberg et al., 2020
40S ribosomal protein S12 P63323 2-132 peptide-Ala25+Leu-peptide N MS Leu Lys Thr Ala Leu Ile His Asp Scharfenberg et al., 2020
40S ribosomal protein S14 P62264 1-151 peptide-Met75+Leu-peptide N MS Tyr Ala Ala Met Leu Ala Ala Gln Scharfenberg et al., 2020
40S ribosomal protein S3a (Protein TU-11) P97351 1-264 peptide-Glu230+Leu-peptide N MS Lys Leu Met Glu Leu His Gly Glu Scharfenberg et al., 2020
A-kinase anchor protein 8 (AKAP-8) (A-kinase anchor protein 95 kDa) (AKAP 95) Q9DBR0 1-687 peptide-Lys619+Leu-peptide N MS His Thr Glu Lys Leu Leu Glu Glu Scharfenberg et al., 2020
Actin, cytoplasmic 1 (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed] P60710 1-375 peptide-Ala7+Leu-peptide N MS Asp Ile Ala Ala Leu Val Val Asp Scharfenberg et al., 2020
ADAM10 O35598 215-749 peptide-Arg623+Thr-peptide N MS Phe Ser Gly Arg Thr Ile Thr Leu Scharfenberg et al., 2020
ADAM10 precursor O35598 20-214 peptide-Arg51+Ala-peptide N MS Arg Ala Lys Arg Ala Val Ser His Scharfenberg et al., 2020
Alanine--tRNA ligase, cytoplasmic (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS) Q8BGQ7 1-968 peptide-Ala803+Thr-peptide N MS Glu Ala Leu Ala Thr Ala Val Ile Scharfenberg et al., 2020
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (Multisynthase complex auxiliary component p38) (Protein J Q8R010 1-320 peptide-Asp40+Ala-peptide N MS Pro Ala Thr Asp Ala Gly His Val Scharfenberg et al., 2020
amyloid beta A4 protein P05067 18-770 peptide-Gln686+Lys-peptide P Val His His Gln Lys Leu Val Phe 18346
amyloid beta A4 protein P05067 18-770 peptide-Lys687+Leu-peptide P His His Gln Lys Leu Val Phe Phe Amour et al., 2002 19794
Amyloid beta A4 protein P05067-4 18-770 peptide-Val636+Ile-peptide P MS Gly Gly Val Val Ile Ala Thr Val Hata et al., 2009
Amyloid beta A4 protein P05067-4 18-770 peptide-Ala638+Thr-peptide P MS Val Val Ile Ala Thr Val Ile Val Hata et al., 2009
Amyloid beta A4 protein P05067-4 18-770 peptide-Lys612+Leu-peptide P MS His His Gln Lys Leu Val Phe Phe Hata et al., 2009 18344
Ankyrin repeat domain-containing protein 17 (Ankyrin repeat domain-containing protein FOE) (Gene trap ankyrin repeat protein) Q99NH0-3 1-1599 peptide-Ala+Val-peptide N MS Ala Ala Ala Ala Val Ala Ala Pro Scharfenberg et al., 2020
Cadherin-2 (Neural cadherin) (N-cadherin) (CD antigen CD325) P15116 160-906 peptide-Thr386+Phe-peptide N MS Thr Ala Met Thr Phe Tyr Gly Glu Scharfenberg et al., 2020
Calsyntenin-1 O94985-2 29 -971 peptide-His814+Met-peptide P MS His Ala Asn His Met Ala Ala Gln Hata et al., 2009
Calsyntenin-1 O94985-2 29 -971 peptide-Ala816+Ala-peptide P MS Asn His Met Ala Ala Gln Pro Gln Hata et al., 2009
Calsyntenin-1 O94985-2 29 -971 peptide-Thr851+Val-peptide P MS Ser Thr Ala Thr Val Val Ile Val Hata et al., 2009
Calsyntenin-1 O94985-2 29 -971 peptide-Ile854+Val-peptide P MS Thr Val Val Ile Val Val Cys Val Hata et al., 2009
Calsyntenin-2 Q9H4D0 21-955 peptide-His803+Leu-peptide P MS His Val Asn His Leu Ile Val Gln Hata et al., 2009
Calsyntenin-2 Q9H4D0 21-955 peptide-Thr834+Val-peptide P MS Ser Ile Ala Thr Val Val Ile Ile Hata et al., 2009
Calsyntenin-2 Q9H4D0 21-955 peptide-Ile837+Ile-peptide P MS Thr Val Val Ile Ile Ile Ser Val Hata et al., 2009
Calsyntenin-3 Q9BQT9 20-956 peptide-His812+Val-peptide P MS His Pro Ser His Val Leu Ser Ser Hata et al., 2009
Calsyntenin-3 Q9BQT9 20-956 peptide-Thr849+Leu-peptide P MS Ser Ala Ala Thr Leu Ile Ile Val Hata et al., 2009
Calsyntenin-3 Q9BQT9 20-956 peptide-Ile852+Val-peptide P MS Thr Leu Ile Ile Val Val Cys Val Hata et al., 2009
CD40 ligand P29965 1-261 peptide-Met113+Gln-peptide P Ser Phe Glu Met Gln Lys Gly Asp Amour et al., 2002
CD40L Lys-Glu-Asn-Ser-Phe-Glu-Met+Gln-Lys-Gly-Ala-Gln N Ser Phe Glu Met Gln Lys Gly Lys Amour et al., 2002
CDKN2A-interacting protein (Collaborator of ARF) Q8BI72 2-563 peptide-Arg121+Gly-peptide N MS Val Lys Lys Arg Gly Ile Ser Ser Scharfenberg et al., 2020
Cellular nucleic acid-binding protein (CNBP) (Zinc finger protein 9) P53996-2 2-178 peptide-Phe38+Val-peptide N MS Gly Phe Gln Phe Val Ser Ser Ser Scharfenberg et al., 2020
CGG triplet repeat-binding protein 1 (CGG-binding protein 1) (20 kDa CGG-binding protein) (p20-CGGBP DNA-binding protein) Q8BHG9 1-167 peptide-Arg70+Lys-peptide N MS His Thr Lys Arg Lys Ala Glu Phe Scharfenberg et al., 2020
Clathrin light chain A (Lca) O08585 1-235 peptide-Arg101+Leu-peptide N MS Glu Val Asp Arg Leu Gln Ser Glu Scharfenberg et al., 2020
Cysteine-rich protein 1 (CRP-1) (Cysteine-rich intestinal protein) (CRIP) P63254 1-77 peptide-Arg16+Val-peptide N MS Phe Ala Glu Arg Val Thr Ser Leu Scharfenberg et al., 2020
Dabcyl-Leu-Ala-Gln-Ala-HPh-Arg-Ser-Lys(Fam)-NH2 Dabcyl-Leu-Ala-Gln-Ala+HPh-Arg-Ser-Lys(Fam)-NH2 S Leu Ala Gln Ala HPh Arg Ser LyN Moss & Rasmussen, 2007
Dabcyl-Pro-Arg-Ala-Ala-Ala-hPhe-Thr-Ser-Pro-Lys(FAM)-NH2 Dabcyl-Pro-Arg-Ala-Ala-Ala+homoPhe-Thr-Ser-Pro-Lys(FAM)-NH2 S Arg Ala Ala Ala HPh Thr Ser Pro Moss et al., 2016
Dabcyl-Pro-Cha-Gly-Cys(Me)-His-Ala-Lys(Fam)-NH2 Dabcyl-Pro-Cha-Gly+Cys(Me)-His-Ala-Lys(Fam)-NH2 S Dab Pro Cha Gly CyM His Ala LyN Moss & Rasmussen, 2007
Dabcyl-Ser-Pro-Leu-Ala-Gln-Ala-Val-Arg-Ser-Ser-Lys(FAM)-NH2 Dabcyl-Ser-Pro-Leu-Ala-Gln-Ala+Val-Arg-Ser-Ser-Lys(FAM)-NH2 S Leu Ala Gln Ala Val Arg Ser Ser Moss et al., 2016
delta-like 1 Q61483 18-722 peptide-His535+Met-peptide P Ser Glu Arg His Met Glu Ser Gln Six et al., 2003 18785
Dickkopf-related protein 3 (Dickkopf-3) (Dkk-3) (mDkk-3) Q9QUN9 23-349 peptide-Thr131+Val-peptide N MS Phe Ser Glu Thr Val Ile Thr Ser Scharfenberg et al., 2020
DNA replication licensing factor MCM2 (EC 3.6.4.12) (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28) P97310 2-904 peptide-Arg133+Gly-peptide N MS Arg Met Arg Arg Gly Leu Leu Tyr Scharfenberg et al., 2020
Dnp-Arg-Ala-Glu-Gln-Gln-Arg-Leu-Lys-Ser-Gln-Asp-Leu P06734 96-107 Dnp-Arg-Ala-Glu-Gln-Gln-Arg+Leu-Lys-Ser-Gln-Asp-Leu S Glu Gln Gln Arg Leu Lys Ser Gln Lemieux et al., 2007 20043
Dnp-Arg-Ala-Glu-Gln-Gln-Arg-Leu-Lys-Ser-Gln-Asp-Leu P06734 96-107 Dnp-Arg-Ala-Glu-Gln+Gln-Arg-Leu-Lys-Ser-Gln-Asp-Leu S Arg Ala Glu Gln Gln Arg Leu Lys Lemieux et al., 2007 20042
Dnp-His-Gly-Asp-Gln-Met-Ala-Gln-Lys-Ser-Gln-Ser-Thr P06734 75-86 Dnp-His-Gly-Asp-Gln-Met-Ala+Gln-Lys-Ser-Gln-Ser-Thr S Asp Gln Met Ala Gln Lys Ser Gln Lemieux et al., 2007 20047
Echinoderm microtubule-associated protein-like 4 (EMAP-4) Q3UMY5-4 1-988 peptide-Pro804+Leu-peptide N MS Pro Ser Leu Pro Leu Thr Gly Thr Scharfenberg et al., 2020
Elongation factor 1-beta (EF-1-beta) O70251 2-225 peptide-Ala40+Val-peptide N MS Val Phe Glu Ala Val Ser Gly Pro Scharfenberg et al., 2020
ephrin type-B receptor 2 P54763 27-994 peptide-Thr543+Ser-peptide P Glu Tyr Gln Thr Ser Ile Lys Glu Litterst et al., 2007 20207
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A Q8R050-2 1-636 peptide-Tyr233+Leu-peptide N MS Gln Ile Met Tyr Leu Thr Gly Met Scharfenberg et al., 2020
Eukaryotic translation initiation factor 1 (eIF1) (Protein translation factor SUI1 homolog) P48024 2-113 peptide-Ala16+Ser-peptide N MS Phe Ala Asp Ala Ser Lys Gly Asp Scharfenberg et al., 2020
Eukaryotic translation initiation factor 2A (eIF-2A) [Cleaved into: Eukaryotic translation initiation factor 2A, N-terminally pr Q8BJW6 1-581 peptide-Val19+Asn-peptide N MS Leu Tyr Met Val Asn Gly Pro Pro Scharfenberg et al., 2020
Eukaryotic translation initiation factor 3 subunit L Q8QZY1 2-564 peptide-Met25+His-peptide N MS Asp Tyr Asp Met His Thr Gly Asp Scharfenberg et al., 2020
Eukaryotic translation initiation factor 5A-1 (eIF-5A-1) (eIF-5A1) (Eukaryotic initiation factor 5A isoform 1) (eIF-5A) (eIF-4D) P63242 2-154 peptide-Leu101+Leu-peptide N MS Tyr Leu Ser Leu Leu Gln Asp Ser Scharfenberg et al., 2020
Ezrin (Cytovillin) (Villin-2) (p81) P26040 1-586 peptide-Gly498+Tyr-peptide N MS Glu Pro Met Gly Tyr Ser Ala Glu Scharfenberg et al., 2020
Ezrin (Cytovillin) (Villin-2) (p81) P26040 1-586 peptide-Arg350+Leu-peptide N MS Leu Met Leu Arg Leu Gln Asp Tyr Scharfenberg et al., 2020
Ezrin (Cytovillin) (Villin-2) (p81) P26040 1-586 peptide-Glu502+Leu-peptide N MS Tyr Ser Ala Glu Leu Ser Ser Glu Scharfenberg et al., 2020
Ezrin (Cytovillin) (Villin-2) (p81) P26040 1-586 peptide-Glu502+Leu-peptide N MS Tyr Ser Ala Glu Leu Ser Ser Glu Scharfenberg et al., 2020
Fatty acid synthase (EC 2.3.1.85) P19096 1-2504 peptide-Arg985+Leu-peptide N MS Ser Val Ser Arg Leu Thr Gln Gly Scharfenberg et al., 2020
Fatty acid synthase (EC 2.3.1.85) P19096 1-2504 peptide-Lys2108+Ala-peptide N MS Ala Glu Lys Lys Ala Val Ala His Scharfenberg et al., 2020
Fibronectin (FN) [Cleaved into: Anastellin] P11276 33-2477 peptide-Pro1654+Ser-peptide N MS Arg Trp Leu Pro Ser Thr Ser Pro Scharfenberg et al., 2020
Flavin reductase (NADPH) (FR) (EC 1.5.1.30) (Biliverdin reductase B) Q923D2 1-206 peptide-Ala162+Tyr-peptide N MS Leu Thr Gly Ala Tyr Thr Val Thr Scharfenberg et al., 2020
Fragile X mental retardation syndrome-related protein 1 (mFxr1p) Q61584-2 2-677 peptide-Asn431+Ser-peptide N MS Tyr Gly Thr Asn Ser Glu Leu Ser Scharfenberg et al., 2020
Fructose-bisphosphate aldolase A (EC 4.1.2.13) (Aldolase 1) (Muscle-type aldolase) P05064 2-364 peptide-Arg43+Leu-peptide N MS Ile Ala Lys Arg Leu Gln Ser Ile Scharfenberg et al., 2020
Glu(EDANS)-Pro-Leu-Ala-Gln-Ala-Val-Arg-Ser-Ser(TF)-Ser-Lys(DABCYL) Glu(EDANS)-Pro-Leu-Ala-Gln-Ala+Val-Arg-Ser-Ser(TF)-Ser-Lys(DABCYL) S Leu Ala Gln Ala Val Arg Ser Ser Minond et al., 2012
Glucosidase 2 subunit beta (80K-H protein) (Glucosidase II subunit beta) (Protein kinase C substrate 60.1 kDa protein heavy chai O08795 15-521 peptide-Ala358+Ile-peptide N MS Glu Thr Gln Ala Ile Ile Asp Ala Scharfenberg et al., 2020
H-2 class I histocompatibility antigen, D-B alpha chain (H-2D(B)) P01899 25-362 peptide-Arg30+Tyr-peptide N MS His Ser Met Arg Tyr Phe Glu Thr Scharfenberg et al., 2020
Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8) P63017 2-646 peptide-Ala180+Ile-peptide N MS Thr Ala Ala Ala Ile Ala Tyr Gly Scharfenberg et al., 2020
Heat shock protein HSP 90-alpha (Heat shock 86 kDa) (HSP 86) (HSP86) (Tumor-specific transplantation 86 kDa antigen) (TSTA) P07901 2-733 peptide-Leu672+Leu-peptide N MS Glu Thr Ala Leu Leu Ser Ser Gly Scharfenberg et al., 2020
Hematological and neurological expressed 1 protein [Cleaved into: Hematological and neurological expressed 1 protein, N-terminal P97825 1-154 peptide-Lys64+Ser-peptide N MS Ser Trp Ala Lys Ser Ala Gly Ser Scharfenberg et al., 2020
Hematological and neurological expressed 1 protein [Cleaved into: Hematological and neurological expressed 1 protein, N-terminal P97825 1-154 peptide-Lys64+Ser-peptide N MS Ser Trp Ala Lys Ser Ala Gly Ser Scharfenberg et al., 2020
heparin-binding EGF-like growth factor precursor Q06186 24-208 peptide-Glu89+Arg-peptide P Pro Ser Lys Glu Arg Asn Gly Lys Hinkle et al., 2004 19483
heparin-binding EGF-like growth factor precursor Q06186 24-208 peptide-Tyr155+Thr-peptide P Asn Pro Leu Tyr Thr Tyr Asp His Hinkle et al., 2004
heparin-binding EGF-like growth factor precursor Q06186 24-208 peptide-Lys99+Gly-peptide P Lys Lys Gly Lys Gly Leu Gly Lys Hinkle et al., 2004
Hepatocyte growth factor-regulated tyrosine kinase substrate Q99LI8 1-775 peptide-Ala268+Leu-peptide N MS Leu Ala Leu Ala Leu Ser Gln Ser Scharfenberg et al., 2020
Heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B) (CArG-binding factor-A) (CBF-A) Q99020 1-285 peptide-Lys131+Val-peptide N MS Ser Val Glu Lys Val Leu Asp Gln Scharfenberg et al., 2020
Histidine triad nucleotide-binding protein 1 P70349 2-126 peptide-Lys30+Ile-peptide N MS Ile Pro Ala Lys Ile Ile Phe Glu Scharfenberg et al., 2020
interleukin-6 receptor subunit alpha P08887 20-468 peptide-Pro355+Val-peptide P NT Thr Ser Leu Pro Val Gln Asp Ser Riethmueller et al., 2016
LIM domain-binding protein 3 (Protein cypher) (Protein oracle) (Z-band alternatively spliced PDZ-motif protein) Q9JKS4-6 1-288 peptide-Ala206+Val-peptide N MS Val Tyr Gln Ala Val Ile Lys Thr Scharfenberg et al., 2020
Macrophage colony-stimulating factor 1 (CSF-1) (MCSF) [Cleaved into: Processed macrophage colony-stimulating factor 1] P07141 33-552 peptide-Pro217+Leu-peptide N MS Ser Met Ala Pro Leu Ala Gly Leu Scharfenberg et al., 2020
major prion protein P04156 23-253 peptide-His111+Met-peptide N Asn Met Lys His Met Ala Gly Ala Laffont-Proust et al., 2005 19686
Major prion protein P04925 23-230 peptide-Gly227+Arg-Arg-Ser P MS Tyr Tyr Asp Gly Arg Arg Ser - Taylor et al., 2009
Melanoma inhibitory activity protein 3 (Transport and Golgi organization protein 1) Q8BI84-2 25-1930 peptide-Ala287+Leu-peptide N MS Thr Ala Asp Ala Leu Val Ser Asp Scharfenberg et al., 2020
meprin A subunit beta Q16820 62-701 peptide-Pro602+Ser-peptide P MS Thr Pro Ala Pro Ser Val Gln Asp Werny et al., 2022
Methionine--tRNA ligase, cytoplasmic (EC 6.1.1.10) (Methionyl-tRNA synthetase) (MetRS) Q68FL6 1-902 peptide-Lys253+Leu-peptide N MS Pro Pro Leu Lys Leu Gln Gln His Scharfenberg et al., 2020
Methylosome subunit pICln Q61189 2-236 Ser-Phe3+Leu-peptide N MS - - Ser Phe Leu Lys Ser Phe Scharfenberg et al., 2020
Microtubule-associated protein 1B (MAP-1B) (MAP1(X)) (MAP1.2) [Cleaved into: MAP1B heavy chain; MAP1 light chain LC1] P14873 2-2464 peptide-Tyr1061+Leu-peptide N MS Gln Tyr Gly Tyr Leu Gly Thr Ser Scharfenberg et al., 2020
Microtubule-associated protein 4 (MAP-4) P27546-4 2-902 peptide-Arg742+Leu-peptide N MS Arg Val Ser Arg Leu Ala Thr Thr Scharfenberg et al., 2020
Microtubule-associated protein RP/EB family member 1 (APC-binding protein EB1) (End-binding protein 1) (EB1) Q61166 2-268 peptide-Lys204+Leu-peptide N MS Lys Val Leu Lys Leu Thr Val Glu Scharfenberg et al., 2020
myelin basic protein P04370 1-250 peptide-Pro73+Gln-peptide P Gly Ser Leu Pro Gln Lys Ser Gln Glynn, 1998 16944
myelin basic protein P02687 1-169 peptide-Pro71+Gln-peptide P Gly Ser Leu Pro Gln Lys Ala Gln Chesneau et al., 2003 20195
myelin basic protein P02687 1-169 peptide-Ala16+Ser-peptide P Leu Ala Ser Ala Ser Thr Met Asp Chesneau et al., 2003 20196
myelin basic protein P02687 1-169 peptide-Ala62+Arg-peptide P His His Ala Ala Arg Thr Thr His Chesneau et al., 2003 20198
Nascent polypeptide-associated complex subunit alpha (Alpha-NAC) (Alpha-NAC/1.9.2) Q60817 1-215 peptide-Leu137+Ala-peptide N MS Gln Ala Gln Leu Ala Ala Ala Ala Scharfenberg et al., 2020
Neurogenic locus notch homolog protein 1 Q01705-1 19-2531 peptide-Ala1710+Val-peptide P AB Lys Ile Glu Ala Val Lys Ser Glu van Tetering et al., 2009
Nexilin (F-actin-binding protein) Q7TPW1 1-607 peptide-Arg520+Asn-peptide N MS Lys Pro Leu Arg Asn Thr Ser Val Scharfenberg et al., 2020
Nuclear autoantigenic sperm protein (NASP) Q99MD9 2-773 peptide-Ala246+Tyr-peptide N MS Ile Ser Gly Ala Tyr Val Gln Asn Scharfenberg et al., 2020
Nuclear autoantigenic sperm protein (NASP) Q99MD9 2-773 peptide-Arg+Lys-peptide N MS Arg Lys Lys Arg Lys Pro Glu Glu Scharfenberg et al., 2020
Nucleolin (Protein C23) P09405 2-707 peptide-Tyr464+Tyr-peptide N MS Val Ser Leu Tyr Tyr Thr Gly Glu Scharfenberg et al., 2020
Olfactomedin-like protein 2B (Photomedin-2) Q3V1G4 21-746 peptide-Arg288+Leu-peptide N MS Leu Arg Gly Arg Leu Ala Ser Lys Scharfenberg et al., 2020
p75NTR P07174 30-425 peptide-Pro242+Val-peptide P Ser Ser Gln Pro Val Val Thr Arg Zampieri et al., 2005 18983
p75NTR P07174 30-425 peptide-Thr245+Arg-peptide P Pro Val Val Thr Arg Gly Thr Thr Zampieri et al., 2005 18984
PCTP-like protein (PCTP-L) Q9JMD3 1-291 peptide-Ala6+Ser-peptide N MS Lys Pro Ala Ala Ser Thr Glu Pro Scharfenberg et al., 2020
Peptidyl-prolyl cis-trans isomerase FKBP4 P30416 1-458 peptide-Lys266+Leu-peptide N MS Ser Ala Glu Lys Leu Glu Gln Ser Scharfenberg et al., 2020
Peptidylprolyl isomerase domain and WD repeat-containing protein 1 (EC 5.2.1.8) Q8CEC6 2-646 peptide-Arg17+Asp-peptide N MS Arg Arg Arg Arg Asp Pro Glu Gly Scharfenberg et al., 2020
Phosphoglycerate mutase 1 (EC 5.4.2.11) (EC 5.4.2.4) (BPG-dependent PGAM 1) (Phosphoglycerate mutase isozyme B) (PGAM-B) Q9DBJ1 1-254 peptide-Arg117+Ser-peptide N MS Ile Trp Arg Arg Ser Tyr Asp Val Scharfenberg et al., 2020
Plasminogen activator inhibitor 1 RNA-binding protein (PAI1 RNA-binding protein 1) (PAI-RBP1) (SERPINE1 mRNA-binding protein 1) Q9CY58-2 1-392 peptide-His206+Tyr-peptide N MS Ser Phe Ser His Tyr Ser Gly Leu Scharfenberg et al., 2020
Probable ATP-dependent RNA helicase DDX6 (EC 3.6.4.13) (ATP-dependent RNA helicase p54) (DEAD box protein 6) (Oncogene RCK homol P54823 1-483 peptide-Gly13+Leu-peptide N MS Val Ile Met Gly Leu Ser Ser Gln Scharfenberg et al., 2020
probetacellulin P35070 1-178 peptide-Ala31+Asp-peptide P NT Cys Val Val Ala Asp Gly Asn Ser Minond et al., 2012
Procollagen C-endopeptidase enhancer 1 Q61398 25-468 peptide-Gly112+Thr-peptide N MS Arg Phe Cys Gly Thr Phe Arg Pro Scharfenberg et al., 2020
prosaposin receptor GPR37 O15354 27-613 peptide-Glu167+Gln-peptide P NT Arg Ser Gln Glu Gln Ser Val Lys Mattila et al., 2021
Protein CDV3 (Carnitine deficiency-associated protein 3) (Tyrosine-phosphorylated protein 36) (TPP36) Q4VAA2-2 2-281 peptide-Gln129+Ile-peptide N MS Gln Ala Met Gln Ile Ser Glu Lys Scharfenberg et al., 2020
Protein disulfide-isomerase A3 P27773 25-505 peptide-Phe171+Leu-peptide N MS His Ser Glu Phe Leu Lys Ala Ala Scharfenberg et al., 2020
Protein lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3) O88952 2-197 peptide-Phe82+Ala-peptide N MS Val Ala Ala Phe Ala Ala Ser Glu Scharfenberg et al., 2020
Protein NDRG2 (N-myc downstream-regulated gene 2 protein) (Protein Ndr2) Q9QYG0-2 2-357 peptide-Ser318+Leu-peptide N MS Arg Thr Ala Ser Leu Thr Ser Ala Scharfenberg et al., 2020
Protein Niban (Protein FAM129A) Q3UW53 2-926 peptide-Ala750+Ile-peptide N MS His Pro Ala Ala Ile Gln Gln Asp Scharfenberg et al., 2020
Protein phosphatase 1 regulatory subunit 14B (Phosphatase holoenzyme inhibitor 1) (PHI-1) (Phospholipase C-beta-3 neighbouring g Q62084 2-147 peptide-Ala15+Leu-peptide N MS Gly Gly Ala Ala Leu Ala Ala Pro Scharfenberg et al., 2020
proTNFalpha peptide Leu-Ala-Gln-Ala+Val-Arg-Ser-Ser N Leu Ala Gln Ala Val Arg Ser Ser Rosendahl et al., 1997
protransforming growth factor alpha precursor P01135 24-160 peptide-Ala39+Val-peptide P Val Ala Ala Ala Val Val Ser His Hinkle et al., 2003 19488
Radixin (ESP10) P26043 1-583 peptide-Arg330+Glu-peptide N MS Lys Lys Lys Arg Glu Ile Ala Glu Scharfenberg et al., 2020
Ran GTPase-activating protein 1 (RanGAP1) P46061 2-589 peptide-Arg55+Leu-peptide N MS Glu Ala Leu Arg Leu Glu Gly Asn Scharfenberg et al., 2020
Ras GTPase-activating protein-binding protein 1 P97855 1-465 peptide-Arg318+Glu-peptide N MS Arg Pro Ile Arg Glu Ala Gly Glu Scharfenberg et al., 2020
Ras GTPase-activating protein-binding protein 2 (G3BP-2) (GAP SH3 domain-binding protein 2) P97379-2 1-482 peptide-Pro237+Ala-peptide N MS Pro Ala Glu Pro Ala Ser Leu Pro Scharfenberg et al., 2020
Rho GDP-dissociation inhibitor 1 (Rho GDI 1) (GDI-1) (Rho-GDI alpha) Q99PT1 2-204 peptide-Lys33+Ser-peptide N MS Pro Ala Gln Lys Ser Ile Gln Glu Scharfenberg et al., 2020
RNA-binding protein EWS Q61545 1-655 peptide-Gly276+Val-peptide N MS Ser Ser Met Gly Val Tyr Gly Gln Scharfenberg et al., 2020
Scaffold attachment factor B1 (SAF-B1) D3YXK2 2-937 peptide-Ala244+Thr-peptide N MS Phe Ala Gln Ala Thr Ser Ser Val Scharfenberg et al., 2020
Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101) Q52KI8-2 1-897 peptide-Ala867+Val-peptide N MS Ala Pro Ala Ala Val Ser Ala Ala Scharfenberg et al., 2020
Serpin H1 (47 kDa heat shock protein) (Collagen-binding protein) (Colligin) (Serine protease inhibitor J6) P19324 18-417 peptide-Lys34+Leu-peptide N MS Thr Ala Glu Lys Leu Ser Ser Lys Scharfenberg et al., 2020
Sorcin Q6P069-2 1-183 peptide-Ala26+Val-peptide N MS Tyr Phe Ala Ala Val Ala Gly Gln Scharfenberg et al., 2020
Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) P16546-2 1-2452 peptide-Gln1490+Leu-peptide N MS Phe Ala Asp Gln Leu Ile Ala Val Scharfenberg et al., 2020
Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) P16546-2 1-2452 peptide-Gln1207+Leu-peptide N MS Glu Arg Ser Gln Leu Leu Gly Ser Scharfenberg et al., 2020
Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Embryonic liver fodrin) (Fodrin beta chain) Q62261 2-2363 peptide-Thr2120+Ser-peptide N MS Gln Trp Asp Thr Ser Lys Gly Asp Scharfenberg et al., 2020
Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Embryonic liver fodrin) (Fodrin beta chain) Q62261 2-2363 peptide-Gln17+Tyr-peptide N MS Ile Gln Gln Gln Tyr Ser Asp Val Scharfenberg et al., 2020
Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (U2 snRNP auxiliary factor large subunit) P26369 2-475 peptide-Pro138+Val-peptide N MS Thr Pro Val Pro Val Val Gly Ser Scharfenberg et al., 2020
Stress-induced-phosphoprotein 1 (STI1) (mSTI1) (Hsc70/Hsp90-organizing protein) (Hop) Q60864 1-543 peptide-Tyr27+Ser-peptide N MS Leu Gln Cys Tyr Ser Glu Ala Ile Scharfenberg et al., 2020
Stress-induced-phosphoprotein 1 (STI1) (mSTI1) (Hsc70/Hsp90-organizing protein) (Hop) Q60864 1-543 peptide-Ala30+Ile-peptide N MS Tyr Ser Glu Ala Ile Lys Leu Asp Scharfenberg et al., 2020
Stress-induced-phosphoprotein 1 (STI1) (mSTI1) (Hsc70/Hsp90-organizing protein) (Hop) Q60864 1-543 peptide-Ala+Val-peptide N MS Asn Gln Ala Ala Val His Phe Glu Scharfenberg et al., 2020
Talin-1 P26039 1-2541 peptide-Tyr1445+Leu-peptide N MS Gln Ala Ala Tyr Leu Val Gly Val Scharfenberg et al., 2020
Talin-1 P26039 1-2541 peptide-Ala1904+Val-peptide N MS Lys Pro Ala Ala Val Ala Ala Glu Scharfenberg et al., 2020
Thrombospondin-4 Q9Z1T2 27-963 peptide-Pro216+Leu-peptide N MS Gln Ser Glu Pro Leu Ala Ala Thr Scharfenberg et al., 2020
Transcription factor Sp5 Q9JHX2 1-398 peptide-Ala34+Leu-peptide N MS Ser Pro Leu Ala Leu Leu Ala Ala Scharfenberg et al., 2020
Transcription intermediary factor 1-beta (TIF1-beta) (E3 SUMO-protein ligase TRIM28) (EC 6.3.2.-) (K Q62318 2-834 peptide-Pro580+Leu-peptide N MS Val Leu Met Pro Leu Thr Glu Gly Scharfenberg et al., 2020
Transketolase (TK) (EC 2.2.1.1) (P68) P40142 1-623 peptide-Lys11+Leu-peptide N MS Asp Gln Gln Lys Leu Gln Ala Leu Scharfenberg et al., 2020
triggering receptor expressed on myeloid cells 2 Q9NZC2 19-230 peptide-His157+Ser-peptide P MS His Val Glu His Ser Ile Ser Arg Thornton et al., 2017
Triosephosphate isomerase (TIM) (EC 5.3.1.1) (Triose-phosphate isomerase) P17751 2-249 peptide-Trp192+Leu-peptide N MS Leu Arg Gly Trp Leu Lys Ser Asn Scharfenberg et al., 2020
Tubulin alpha-1B chain (Alpha-tubulin 2) (Alpha-tubulin isotype M-alpha-2) (Tubulin alpha-2 chain) [ P05213 1-451 peptide-Gln91+Leu-peptide N MS His Pro Glu Gln Leu Ile Thr Gly Scharfenberg et al., 2020
tumor necrosis factor P01375 1-233 peptide-Ala76+Val-peptide P Leu Ala Gln Ala Val Arg Ser Ser Rosendahl et al., 1997 18021
Tumor necrosis factor ligand superfamily member 11 O35235 1-316 peptide-Arg138+Phe-peptide P NT Gly Pro Gln Arg Phe Ser Gly Ala Hikita et al., 2006
tumor-associated calcium signal transducer 2 P09758 27-323 peptide-Arg87+Thr-peptide P NT Lys Asn Ala Arg Thr Leu Val Arg
Twinfilin-1 (Protein A6) Q91YR1 2-350 peptide-Pro146+Leu-peptide N MS Ser Pro Ala Pro Leu Thr Ala Ala Scharfenberg et al., 2020
U5 small nuclear ribonucleoprotein 40 kDa protein (U5 snRNP 40 kDa protein) (WD repeat-containing protein 57) Q6PE01 1-358 peptide-Gly27+Ala-peptide N MS Leu Leu Leu Gly Ala Ala Gly Ala Scharfenberg et al., 2020
Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.4.19.12) (Deubiquitinating enzyme 5) (Isopeptidase T) P56399 2-858 peptide-Ala419+Leu-peptide N MS Met Phe Lys Ala Leu Ile Gly Lys Scharfenberg et al., 2020
Ubiquitin-like modifier-activating enzyme 1 Q02053 2-1058 peptide-Phe861+Ile-peptide N MS His Met Asp Phe Ile Val Ala Ala Scharfenberg et al., 2020
Vimentin P20152 2-466 peptide-Ala332+Leu-peptide N MS Glu Val Asp Ala Leu Lys Gly Thr Scharfenberg et al., 2020
Vimentin P20152 2-466 peptide-Pro432+Leu-peptide N MS Glu Ser Leu Pro Leu Val Asp Thr Scharfenberg et al., 2020
Zinc finger protein ZPR1 (Zinc finger protein 259) Q62384 1-459 peptide-Gly237+Leu-peptide N MS Glu Met Leu Gly Leu Gln Ala Glu Scharfenberg et al., 2020
Zinc finger RNA-binding protein O88532 1-1074 peptide-Ala556+Leu-peptide N MS Ser Leu Ala Ala Leu Gln Ser Asp Scharfenberg et al., 2020

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