Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence P17751

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
75	cathepsin E	2-299	P		MS	Impens et al., 2010
79	cathepsin D	2-299	P		MS	Impens et al., 2010
79	cathepsin E	2-299	P		MS	Impens et al., 2010
133	matrix metallopeptidase-2	2-299	N		MS	auf dem Keller et al., 2010
138	matrix metallopeptidase-2	2-299	N		MS	Prudova et al., 2010
140	matrix metallopeptidase-2	2-299	N		MS	auf dem Keller et al., 2010
141	cathepsin E	2-299	P		MS	Impens et al., 2010
173	matrix metallopeptidase-2	2-299	N		MS	auf dem Keller et al., 2010
177	cathepsin D	2-299	P		MS	Impens et al., 2010
177	cathepsin E	2-299	P		MS	Impens et al., 2010
212	carboxypeptidase A4	199-213	P		MS	Tanco et al., 2010
219	cathepsin D	2-299	P		MS	Impens et al., 2010
219	matrix metallopeptidase-2	2-299	N		MS	Kleifeld et al., 2010
229	matrix metallopeptidase-2	2-299	N		MS	Kleifeld et al., 2010
242	matrix metallopeptidase-2	2-299	N		MS	Prudova et al., 2010
246	cathepsin E	2-299	P		MS	Impens et al., 2010
280	matrix metallopeptidase-2	2-299	N		MS	Kleifeld et al., 2010