Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence P01375

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
34	signal peptide peptidase-like protein 2B	1-233	P	release from a membrane surface		Fluhrer et al., 2006
35	unknown peptidase	1-233	P		NT	<%Agarwal et al., 2012[]%>
39	signal peptide peptidase-like protein 2B	1-233	P	release from a membrane surface		Fluhrer et al., 2006
49	signal peptide peptidase-like protein 2B	1-233	P	release from a membrane surface		Fluhrer et al., 2006
51	signal peptide peptidase-like protein 2B	1-233	P	release from a membrane surface		Fluhrer et al., 2006
69	membrane-type matrix metallopeptidase-1	1-233	P			Tam et al., 2004
72	membrane-type matrix metallopeptidase-1	1-233	P			Tam et al., 2004
74	membrane-type matrix metallopeptidase-1	1-233	P			Tam et al., 2004
74	ADAM8 peptidase	1-233	P			Amour et al., 2002
74	ADAM9 peptidase	1-233	P			Amour et al., 2002
75	membrane-type matrix metallopeptidase-4	1-233	P			Amour et al., 2002
76	membrane-type matrix metallopeptidase-1	1-233	P			Tam et al., 2004
76	ADAM8 peptidase	1-233	P			Amour et al., 2002
76	ADAM10 peptidase	1-233	P			Rosendahl et al., 1997
76	ADAM17 peptidase	1-233	P			<%Mohan et al., 2002[]%>
78	gingipain RgpA	77-233	N			Calkins et al., 1998
78	gingipain RgpB	77-233	P			Calkins et al., 1998
78	ADAM19 peptidase	1-233	P			Chesneau et al., 2003
79	ADAM9 peptidase	1-233	P			Amour et al., 2002
79	ADAM19 peptidase	1-233	P			Chesneau et al., 2003
82	gingipain RgpA	77-233	N			Calkins et al., 1998
82	gingipain RgpB	77-233	P			Calkins et al., 1998
108	gingipain RgpB	77-233	P			Calkins et al., 1998
141	gingipain K	77-233	P			Calkins et al., 1998
166	gingipain K	77-233	P			Calkins et al., 1998
174	gingipain K	77-233	P			Calkins et al., 1998