Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence Q99020

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
100	matrix metallopeptidase-2	1-285	N		MS	auf dem Keller et al., 2010
103	cathepsin D	1-285	P		MS	Impens et al., 2010
105	cathepsin E	1-285	P		MS	Impens et al., 2010
120	cathepsin E	1-285	P		MS	Impens et al., 2010
122	cathepsin D	1-285	P		MS	Impens et al., 2010
122	cathepsin E	1-285	P		MS	Impens et al., 2010
123	cathepsin D	1-285	P		MS	Impens et al., 2010
152	matrix metallopeptidase-2	1-285	N		MS	Kleifeld et al., 2010
177	matrix metallopeptidase-2	1-285	N		MS	auf dem Keller et al., 2010
184	matrix metallopeptidase-2	1-285	N		MS	auf dem Keller et al., 2010
186	cathepsin E	1-285	P		MS	Impens et al., 2010
187	cathepsin D	1-285	P		MS	Impens et al., 2010
187	cathepsin E	1-285	P		MS	Impens et al., 2010
190	cathepsin E	1-285	P		MS	Impens et al., 2010
230	cathepsin E	1-285	P		MS	Impens et al., 2010