Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence P20152

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-466	P		NT	<%Agarwal et al., 2012[]%>
19	calpain-2	2-466	P			Fischer et al., 1986
21	calpain-2	2-466	P			Fischer et al., 1986
33	calpain-2	2-466	P			Fischer et al., 1986
38	calpain-2	2-466	P			Fischer et al., 1986
41	calpain-2	2-466	P			Fischer et al., 1986
53	calpain-2	2-466	P			Fischer et al., 1986
64	calpain-2	2-466	P			Fischer et al., 1986
71	calpain-2	2-466	P			Fischer et al., 1986
82	granzyme B (Homo sapiens-type)	2-466	N			Van Damme et al., 2009
82	granzyme B, rodent-type	2-466	P			Van Damme et al., 2009
85	caspase-3	2-466	N		MS	Demon et al., 2009
85	caspase-7	2-466	N		MS	Demon et al., 2009
86	cathepsin D	2-466	P		MS	Impens et al., 2010
86	cathepsin E	2-466	P		MS	Impens et al., 2010
88	cathepsin D	2-466	P		MS	Impens et al., 2010
88	cathepsin E	2-466	P		MS	Impens et al., 2010
100	trypsin 1	2-466	N			Van Damme et al., 2009
106	cathepsin E	2-466	P		MS	Impens et al., 2010
113	matrix metallopeptidase-2	2-466	N		MS	Prudova et al., 2010
175	matrix metallopeptidase-2	2-466	N		MS	Kleifeld et al., 2010
205	matrix metallopeptidase-2	2-466	N		MS	Kleifeld et al., 2010
244	matrix metallopeptidase-2	2-466	N		MS	Kleifeld et al., 2010
257	matrix metallopeptidase-2	2-466	N		MS	Kleifeld et al., 2010
283	matrix metallopeptidase-2	2-466	N		MS	Prudova et al., 2010
289	matrix metallopeptidase-2	2-466	N		MS	auf dem Keller et al., 2010
325	matrix metallopeptidase-2	2-466	N		MS	Kleifeld et al., 2010
332	matrix metallopeptidase-2	2-466	N		MS	auf dem Keller et al., 2010
422	matrix metallopeptidase-2	2-466	N		MS	Kleifeld et al., 2010