Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Sequence P05064

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Evidence	Reference
1	unknown peptidase	1-364	P	NT	<%Agarwal et al., 2012[]%>
30	matrix metallopeptidase-2	2-364	N	MS	auf dem Keller et al., 2010
31	cathepsin D	2-364	P	MS	Impens et al., 2010
31	cathepsin E	2-364	P	MS	Impens et al., 2010
33	cathepsin D	2-364	P	MS	Impens et al., 2010
33	cathepsin E	2-364	P	MS	Impens et al., 2010
34	cathepsin E	2-364	P	MS	Impens et al., 2010
43	matrix metallopeptidase-2	2-364	N	MS	auf dem Keller et al., 2010
45	matrix metallopeptidase-2	2-364	N	MS	auf dem Keller et al., 2010
46	matrix metallopeptidase-2	2-364	N	MS	auf dem Keller et al., 2010
61	matrix metallopeptidase-2	2-364	N	MS	auf dem Keller et al., 2010
115	matrix metallopeptidase-2	2-364	N	MS	auf dem Keller et al., 2010
118	matrix metallopeptidase-2	2-364	N	MS	auf dem Keller et al., 2010
152	cathepsin E	2-364	P	MS	Impens et al., 2010
162	cathepsin E	2-364	P	MS	Impens et al., 2010
174	cathepsin E	2-364	P	MS	Impens et al., 2010
185	cathepsin D	2-364	P	MS	Impens et al., 2010
185	matrix metallopeptidase-2	2-364	N	MS	auf dem Keller et al., 2010
320	matrix metallopeptidase-2	2-364	N	MS	auf dem Keller et al., 2010
321	cathepsin E	2-364	P	MS	Impens et al., 2010
321	matrix metallopeptidase-2	2-364	N	MS	auf dem Keller et al., 2010