Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P26369

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-475	P		NT	<%Agarwal et al., 2012[]%>
128	caspase-3	2-475	N		MS	Demon et al., 2009
128	caspase-7	2-475	N		MS	Demon et al., 2009
128	granzyme B (Homo sapiens-type)	2-475	N			Van Damme et al., 2009
128	granzyme B, rodent-type	2-475	P	normal turnover		Van Damme et al., 2009
130	unknown peptidase	2-475	P			Van Damme et al., 2009
132	caspase-1	2-475	P		MS	Lamkanfi et al., 2008
146	trypsin 1	2-475	N			Van Damme et al., 2009