Structure for peptidase M12.210: ADAM10 peptidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors Pharma

 

TERTIARY STRUCTURE DATA
Comment Resolution PDB PDBe SCOP CATH PDBSum Proteopedia Reference
Bos taurus
mature  peptidase 2.90 Å 2AO7 2AO7 2AO7 2AO7 2AO7 2AO7 Mancia & Shapiro, 2005
D+C domain; complex with a conformation specific mab 8c7. 2.76 Å 5L0Q 5L0Q 5L0Q 5L0Q 5L0Q 5L0Q
Homo sapiens
mature  peptidase 0.00 Å 1M1I 1M1I 1M1I 1M1I 1M1I 1M1I
adam10 extracellular domain bound by the 11g2 fab 3.10 Å 6BDZ 6BDZ 6BDZ 6BDZ 6BDZ 6BDZ
extracellular domain 2.80 Å 6BE6 6BE6 6BE6 6BE6 6BE6 6BE6