Structure for peptidase M12.210: ADAM10 peptidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

 

TERTIARY STRUCTURE DATA
Comment Resolution PDB PDBe SCOP CATH PDBSum Proteopedia Reference
Bos taurus
mature  peptidase 2.90 Å 2AO7 2AO7 2AO7 2AO7 2AO7 2AO7 Mancia & Shapiro, 2005
D+C domain; complex with a conformation specific mab 8c7. 2.76 Å 5L0Q 5L0Q 5L0Q 5L0Q 5L0Q 5L0Q
Homo sapiens
mature  peptidase 0.00 Å 1M1I 1M1I 1M1I 1M1I 1M1I 1M1I
adam10 extracellular domain bound by the 11g2 fab 3.10 Å 6BDZ 6BDZ 6BDZ 6BDZ 6BDZ 6BDZ
extracellular domain 2.80 Å 6BE6 6BE6 6BE6 6BE6 6BE6 6BE6