Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence P04370

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
34	matrix metallopeptidase-9	1-190	P		MS	Shiryaev et al., 2009
34	membrane-type matrix metallopeptidase-1	1-246	P			Shiryaev et al., 2009
34	membrane-type matrix metallopeptidase-6	1-246	P			Shiryaev et al., 2009
75	matrix metallopeptidase-8	1-246	P			Shiryaev et al., 2009
75	matrix metallopeptidase-9	1-190	P		MS	Shiryaev et al., 2009
75	matrix metallopeptidase-10 (Homo sapiens-type)	1-246	P			Shiryaev et al., 2009
75	matrix metallopeptidase-12	1-246	P			Shiryaev et al., 2009
75	membrane-type matrix metallopeptidase-1	1-246	P			Shiryaev et al., 2009
75	membrane-type matrix metallopeptidase-2	1-246	P			Shiryaev et al., 2009
75	membrane-type matrix metallopeptidase-3	1-246	P			Shiryaev et al., 2009
75	membrane-type matrix metallopeptidase-4	1-246	P			Shiryaev et al., 2009
75	membrane-type matrix metallopeptidase-6	1-246	P			Shiryaev et al., 2009
87	matrix metallopeptidase-2	1-246	P			Shiryaev et al., 2009
87	matrix metallopeptidase-9	1-190	P		MS	Shiryaev et al., 2009
87	membrane-type matrix metallopeptidase-1	1-246	P			Shiryaev et al., 2009
87	membrane-type matrix metallopeptidase-4	1-246	P			Shiryaev et al., 2009
113	membrane-type matrix metallopeptidase-1	1-246	P			Shiryaev et al., 2009
116	matrix metallopeptidase-8	1-246	P			Shiryaev et al., 2009
116	matrix metallopeptidase-2	1-246	P			Shiryaev et al., 2009
116	matrix metallopeptidase-9	1-246	P			Shiryaev et al., 2009
116	matrix metallopeptidase-10 (Homo sapiens-type)	1-246	P			Shiryaev et al., 2009
116	matrix metallopeptidase-12	1-246	P			Shiryaev et al., 2009
116	membrane-type matrix metallopeptidase-1	1-246	P			Shiryaev et al., 2009
116	membrane-type matrix metallopeptidase-2	1-246	P			Shiryaev et al., 2009
116	membrane-type matrix metallopeptidase-3	1-246	P			Shiryaev et al., 2009
116	membrane-type matrix metallopeptidase-4	1-246	P		MS	Shiryaev et al., 2009
116	membrane-type matrix metallopeptidase-6	1-246	P			Shiryaev et al., 2009
119	matrix metallopeptidase-9	1-190	P		MS	Shiryaev et al., 2009
126	matrix metallopeptidase-2	1-246	P			Shiryaev et al., 2009
126	matrix metallopeptidase-12	1-246	P			Shiryaev et al., 2009
126	membrane-type matrix metallopeptidase-1	1-246	P			Shiryaev et al., 2009
126	membrane-type matrix metallopeptidase-6	1-246	P			Shiryaev et al., 2009
135	membrane-type matrix metallopeptidase-4	1-246	P		MS	Shiryaev et al., 2009
135	membrane-type matrix metallopeptidase-6	1-246	P			Shiryaev et al., 2009
136	membrane-type matrix metallopeptidase-1	1-246	P			Shiryaev et al., 2009
136	membrane-type matrix metallopeptidase-4	1-246	P		MS	Shiryaev et al., 2009
136	membrane-type matrix metallopeptidase-6	1-246	P			Shiryaev et al., 2009
144	matrix metallopeptidase-8	1-246	P			Shiryaev et al., 2009
144	matrix metallopeptidase-9	1-246	P			Shiryaev et al., 2009
144	matrix metallopeptidase-12	1-246	P			Shiryaev et al., 2009
144	membrane-type matrix metallopeptidase-1	1-246	P			Shiryaev et al., 2009
144	membrane-type matrix metallopeptidase-3	1-246	P			Shiryaev et al., 2009
144	membrane-type matrix metallopeptidase-4	1-246	P		MS	Shiryaev et al., 2009
144	membrane-type matrix metallopeptidase-6	1-246	P			Shiryaev et al., 2009
146	matrix metallopeptidase-9	1-190	P		MS	Shiryaev et al., 2009
146	membrane-type matrix metallopeptidase-4	1-246	P		MS	Shiryaev et al., 2009
147	carboxypeptidase A6	135-148	N			Lyons & Fricker, 2010
149	carboxypeptidase A6	135-150	N			Lyons & Fricker, 2010
150	matrix metallopeptidase-9	1-246	P			Shiryaev et al., 2009
150	membrane-type matrix metallopeptidase-1	1-246	P		MS	Shiryaev et al., 2009
150	membrane-type matrix metallopeptidase-2	1-246	P			Shiryaev et al., 2009
150	membrane-type matrix metallopeptidase-3	1-246	P			Shiryaev et al., 2009
158	matrix metallopeptidase-9	1-246	P			Shiryaev et al., 2009
158	membrane-type matrix metallopeptidase-1	1-246	P			Shiryaev et al., 2009
158	membrane-type matrix metallopeptidase-4	1-246	P			Shiryaev et al., 2009
158	membrane-type matrix metallopeptidase-6	1-246	P			Shiryaev et al., 2009
164	matrix metallopeptidase-9	1-190	P		MS	Shiryaev et al., 2009
172	membrane-type matrix metallopeptidase-2	1-246	P			Shiryaev et al., 2009
175	membrane-type matrix metallopeptidase-1	1-246	P			Shiryaev et al., 2009
201	matrix metallopeptidase-9	1-246	P			Shiryaev et al., 2009
201	membrane-type matrix metallopeptidase-1	1-246	P			Shiryaev et al., 2009
203	matrix metallopeptidase-8	1-246	P			Shiryaev et al., 2009
203	matrix metallopeptidase-2	1-246	P			Shiryaev et al., 2009
203	matrix metallopeptidase-9	1-246	P			Shiryaev et al., 2009
203	matrix metallopeptidase-10 (Homo sapiens-type)	1-246	P			Shiryaev et al., 2009
203	matrix metallopeptidase-12	1-246	P			Shiryaev et al., 2009
203	membrane-type matrix metallopeptidase-1	1-246	P			Shiryaev et al., 2009
203	membrane-type matrix metallopeptidase-2	1-246	P			Shiryaev et al., 2009
203	membrane-type matrix metallopeptidase-3	1-246	P			Shiryaev et al., 2009
203	membrane-type matrix metallopeptidase-4	1-246	P			Shiryaev et al., 2009
203	membrane-type matrix metallopeptidase-6	1-246	P			Shiryaev et al., 2009
203	ADAM8 peptidase	1-250	P			Amour et al., 2002
203	ADAM10 peptidase	1-250	P			Glynn, 1998
205	matrix metallopeptidase-8	1-246	P			Shiryaev et al., 2009
205	matrix metallopeptidase-9	1-246	P			Shiryaev et al., 2009
205	matrix metallopeptidase-10 (Homo sapiens-type)	1-246	P			Shiryaev et al., 2009
205	matrix metallopeptidase-12	1-246	P			Shiryaev et al., 2009
205	membrane-type matrix metallopeptidase-1	1-246	P			Shiryaev et al., 2009
205	membrane-type matrix metallopeptidase-2	1-246	P			Shiryaev et al., 2009
205	membrane-type matrix metallopeptidase-3	1-246	P			Shiryaev et al., 2009
205	membrane-type matrix metallopeptidase-4	1-246	P			Shiryaev et al., 2009
205	membrane-type matrix metallopeptidase-6	1-246	P			Shiryaev et al., 2009
208	matrix metallopeptidase-8	1-246	P			Shiryaev et al., 2009
208	matrix metallopeptidase-12	1-246	P			Shiryaev et al., 2009
208	membrane-type matrix metallopeptidase-1	1-246	P			Shiryaev et al., 2009
208	membrane-type matrix metallopeptidase-3	1-246	P			Shiryaev et al., 2009
208	membrane-type matrix metallopeptidase-4	1-246	P			Shiryaev et al., 2009
208	membrane-type matrix metallopeptidase-6	1-246	P			Shiryaev et al., 2009
246	membrane-type matrix metallopeptidase-6	1-250	N		MS	Shiryaev et al., 2009