|Family type peptidase||U56.001 - homomultimeric peptidase (Thermotoga maritima), MEROPS Accession MER0005216 (peptidase unit: 1-259)|
|Content of family||Family U56 contains endopeptidases.|
Identifier created: MEROPS 8.2 (4 August 2008)|
Familu U56 contains the homomultimeric peptidase (U56.001) from the hyperthermophilic bacterium Thermotoga maritima, which is so named because it consists of many identical subunits and forms a complex with a size in excess of 780 kDa. Individual subunits are 31 kDa (<%Hicks et al., 199820040510N921]%>.
|Catalytic type||Peptidase of unknown catalytic type|
|Active site||Neither active site residues nor the catalytic type have been determined.|
|Activities and specificities||The homomultimeric peptidase is able to hydrolyse substrates of chymotrypsin (S01.001) (such as substrate Val-Lys-Met-NHMec), trypsin (S01.151) and casein. Optimal conditions for activity are 90°C and pH 7.1 (<%Hicks et al., 199820040510N921]%>).|
|Molecular structure||The homomultimeric peptidase is visible under transmission electron microscopy showing a large globular assembly (<%Hicks et al., 199820040510N921]%>). It is not known how many subunits exist in the homomultimer. The amino acid sequence shows no relationship to any other peptidase.|