Family U56


Summary Holotypes Alignment Tree Genomes Structure Literature

Summary for family U56

Family type peptidaseU56.001 - homomultimeric peptidase (Thermotoga maritima), MEROPS Accession MER0005216 (peptidase unit: 1-259)
Content of familyFamily U56 contains endopeptidases.
History Identifier created: MEROPS 8.2 (4 August 2008)
Familu U56 contains the homomultimeric peptidase (U56.001) from the hyperthermophilic bacterium Thermotoga maritima, which is so named because it consists of many identical subunits and forms a complex with a size in excess of 780 kDa. Individual subunits are 31 kDa (<%Hicks et al., 199820040510N921]%>.
Catalytic typePeptidase of unknown catalytic type
Active siteNeither active site residues nor the catalytic type have been determined.
Activities and specificitiesThe homomultimeric peptidase is able to hydrolyse substrates of chymotrypsin (S01.001) (such as substrate Val-Lys-Met-NHMec), trypsin (S01.151) and casein. Optimal conditions for activity are 90°C and pH 7.1 (<%Hicks et al., 199820040510N921]%>).
Molecular structureThe homomultimeric peptidase is visible under transmission electron microscopy showing a large globular assembly (<%Hicks et al., 199820040510N921]%>). It is not known how many subunits exist in the homomultimer. The amino acid sequence shows no relationship to any other peptidase.
Distribution of family Bacteria details  
Archaea details  
Protozoa -  
Fungi -  
Plants -  
Animals details  
Viruses -  
Biological functions
Statistics for family U56Sequences:235
Identifiers with PDB entries:1
Downloadable files Sequence library (FastA format)
Sequence alignment (FastA format)
Phylogenetic tree (Newick format)
Other databases PANTHER PTHR37165
PFAM PF04454
Peptidases and Homologues MEROPS ID Structure
homomultimeric peptidaseU56.001Yes
family U56 unassigned peptidasesunassigned-