Summary for clan MP
| Clan type peptidase | M67.010 - JAMM-like protein (Archaeoglobus-type) (Archaeoglobus fulgidus), MEROPS Accession MER0031571 (peptidase unit: 1-121); PDB accession 1OI0_A |
| History | MEROPS 6.6 (27 March 2004) |
| Description | Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D) |
| Contents of clan | Clan MP contains metallopeptidases in the single family M67. |
| Evidence | The protein fold of JAMM-like protein (M67.010) from Archeaoglobus fulgidus is unlike that of any other peptidase, and family M67 is the single family in clan MP. |
| Catalytic mechanism | (See family M67.) |
| Peptidase activity | Known activities are isopeptidase (see family M67). |
| Protein fold | The tertiary structure determined for JAMM-like protein shows a single domain consisting of a five-stranded beta sheet (in the order 21345, with strand two antiparallel to the rest) located between two helices (Tran et al., 2003). |
| Homologous non-peptidase families | Cytidine deaminase has a similar fold (see SCOP sunid 53926). |
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Other databases
| SCOP | 102712 |
Families
| M67 |
PSMD14 peptidase (Saccharomyces cerevisiae) |
Yes |
Distribution of clan MP among Kingdoms of Organisms
