Summary for clan NB
| Clan type peptidase | N06.001 - YscU protein (Yersinia pestis), MEROPS Accession MER0187112 (peptidase unit: 1-354); PDB accession 2JLJ |
| History | MEROPS 9.3 (7 September 2010) |
| Description | Asparagine nucleophile; all self-processing endopeptidases |
| Contents of clan | Peptidase clan NB contains autolytic endopeptidases. |
| Evidence | The tertiary fold for members of clan NB is unique. The structures of the C-terminal domains from EscU (Escherichia coli) and SpaS (Salmonella typhimurium) have been determined (Zarivach et al., 2008). |
| Catalytic mechanism | (see family N6) |
| Peptidase activity | (see family N6) |
| Evolution | The tertiary fold is unrelated to that of any other protein. |
Families
| N6 |
YscU protein (Yersinia pseudotuberculosis) |
Yes |
Distribution of clan NB among Kingdoms of Organisms