Summary for clan NB

Summary Structure Literature
Clan type peptidaseN06.001 - YscU protein (Yersinia pestis), MEROPS Accession MER0187112 (peptidase unit: 1-354); PDB accession 2JLJ
HistoryMEROPS 9.3 (7 September 2010)
DescriptionAsparagine nucleophile; all self-processing endopeptidases
Contents of clanPeptidase clan NB contains autolytic endopeptidases.
EvidenceThe tertiary fold for members of clan NB is unique. The structures of the C-terminal domains from EscU (Escherichia coli) and SpaS (Salmonella typhimurium) have been determined (Zarivach et al., 2008).
Catalytic mechanism(see family N6)
Peptidase activity(see family N6)
EvolutionThe tertiary fold is unrelated to that of any other protein.


Family Family Type Peptidase Structure
N6 YscU protein (Yersinia pseudotuberculosis) Yes

Distribution of clan NB among Kingdoms of Organisms