Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence P30990

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
2	ALE1 peptidase	24-148	P			Cedzich et al., 2009
23	unknown peptidase	1-170	P		NT	<%Agarwal et al., 2012[]%>
148	unknown peptidase	1-170	P		NT	<%Agarwal et al., 2012[]%>
151	pyroglutamyl-peptidase I (chordate)	151-163	N			De Gandarias et al., 1994
152	endothelin-converting enzyme 1	151-163	N			Carson et al., 2002
152	Zmp1 peptidase (Mycobacterium-type)	151-163	N			Carson et al., 2002
152	penicillolysin	151-163	N			Ichishima, 2004
152	SlSBT3 g.p. (Solanum lycopersicum)	151-163	N			Cedzich et al., 2009
152	family S10 unassigned peptidases	151-153	N		NT	Umetsu et al., 1998
153	calpain-1	151-163	N			McDermott et al., 1985
153	meprin alpha subunit	151-163	N			Bylander et al., 2007
153	Zmp1 peptidase (Mycobacterium-type)	151-163	N			Carson et al., 2002
153	family S10 unassigned peptidases	151-154	N		NT	Umetsu et al., 1998
153	tripeptidyl-peptidase I	151-163	N			Du et al., 2001
154	EcpA peptidase	151-163	N			Oleksy et al., 2004
154	oligopeptidase F	151-163	N		MS	Chao et al., 2006
154	meprin alpha subunit	151-163	N			Bylander et al., 2007
154	family S10 unassigned peptidases	151-155	N		NT	Umetsu et al., 1998
155	legumain, animal-type	151-163	N			Chen et al., 2004
155	family S10 unassigned peptidases	151-156	N		NT	Umetsu et al., 1998
156	gingipain K	151-163	N			Pike et al., 1994
156	sporangin	151-163	N			Matsuda et al., 1995
156	family S10 unassigned peptidases	151-157	N		NT	Umetsu et al., 1998
157	angiotensin-converting enzyme-2	151-158	P		MS	Vickers et al., 2002
157	penicillolysin	151-163	N
157	family S10 unassigned peptidases	151-158	N		NT	Umetsu et al., 1998
158	thimet oligopeptidase	151-163	N			Barrett & Chen, 2004
158	oligopeptidase F	151-163	N			Pritchard, 2004
158	Pz-peptidase A	151-163	N			Miyake et al., 2005
158	epralysin	151-163	N			Kim et al., 1997
158	meprin alpha subunit	151-163	N			Bylander et al., 2007
158	penicillolysin	151-163	N			Ichishima, 2004
158	family S10 unassigned peptidases	151-159	N		NT	Umetsu et al., 1998
158	tryase	151-163	P		NT	Tamanoue, et al., 1993
158	unknown peptidase	151-163	N			Tsuchiya et al., 1994
159	oligopeptidase B	151-163	P			Troeberg et al., 1996
159	family S10 unassigned peptidases	151-160	N		NT	Umetsu et al., 1998
160	neurolysin	151-163	N			Barrett & Dando, 2004
160	oligopeptidase F	151-163	N			Pritchard, 2004
160	Pz-peptidase A	151-163	N			Miyake et al., 2005
160	gametolysin	151-163	N			Matsuda & Kubo, 2004
160	neprilysin	151-163	N			Turner, 2004
160	endothelin-converting enzyme 1	151-163	N			Ahn & Johnson, 2004
160	endothelin-converting enzyme 2	24-148	P		MS	Mzhavia et al., 2003
160	family S10 unassigned peptidases	151-161	N		NT	Umetsu et al., 1998
161	cathepsin B	157-163	N			Takahashi et al., 1986
161	neprilysin	151-163	N			Turner, 2004
161	endothelin-converting enzyme 2	24-148	P		MS	Mzhavia et al., 2003
161	chymase (Homo sapiens-type)	151-163	P			Raymond et al., 2003
161	family S10 unassigned peptidases	151-162	N		NT	Umetsu et al., 1998
161	unknown peptidase	151-163	N			Skidgel & Erdös, 2004
161	unknown peptidase	151-163	N			Bertenshaw & Bond, 2004
162	angiotensin-converting enzyme-2	151-163	P		MS	Donoghue et al., 2000
162	carboxypeptidase A4	151-163	N			Tanco et al., 2010
162	carboxypeptidase A6	151-163	P		MS	Lyons et al., 2008
162	family S10 unassigned peptidases	151-163	N		NT	Umetsu et al., 1998