Substrates for peptidase M11.001: gametolysin

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
alpha-neoendorphin P01213 175-184 Tyr-Gly-Gly-Phe+Leu-Arg-Lys-Tyr-Pro-Lys N Tyr Gly Gly Phe Leu Arg Lys Tyr Matsuda & Kubo, 2004 16680
dynorphin A(1-13) P01214 209-221 Tyr-Gly-Gly-Phe+Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys N Tyr Gly Gly Phe Leu Arg Arg Ile Matsuda & Kubo, 2004
gametolysin P31178 29-183 peptide-Lys183+Glu-peptide P Gly Ser Gln Lys Glu Ile Tyr Ala Kinoshita et al., 1992 18110
Leu-Trp-Met-Arg-Phe-Ala Leu-Trp-Met+Arg-Phe-Ala N - Leu Trp Met Arg Phe Ala -
mastoparan-L P01514 1-14 Ile-Asn-Leu-Lys-Ala-Leu-Ala+Ala-Leu-Ala-Lys-Lys P Lys Ala Leu Ala Ala Leu Ala Lys Matsuda & Kubo, 2004 16681
mastoparan-L P01514 1-14 Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala+Leu-Ala-Lys-Lys P Ala Leu Ala Ala Leu Ala Lys Lys Matsuda & Kubo, 2004 16682
neurotensin P30990 151-163 Glp-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro+Tyr-Ile-Leu N Pro Arg Arg Pro Tyr Ile Leu - Matsuda & Kubo, 2004 16683