Chart Builder
Introduction
The EMDB Chart Builder (https://emdb-empiar.org/statistics/builder) is a web-based application that provides users with the ability to create customizable, dynamic, and informative charts that help analyse the holdings and trends of the EMDB and EMPIAR archives, powered by the EMDB search engine. The underlying data is based on the metadata of all EMDB entries, enriched by the EMICSS resource (https://emdb-empiar.org/emicss). This tool allows users to define specific search terms, enabling the extraction of data subsets that are directly relevant to their analysis objectives. By organising the extracted data into meaningful categories, users can generate insightful charts to visualise and analyse the results. The Chart Builder can be accessed at https://ebi.ac.uk/emdb/statistics/builder.This page presents a user-friendly interface specifically designed to facilitate the creation of customised charts using both EMDB and EMPIAR data.
Use of the Chart Builder requires some knowledge of the EMDB search engine. Therefore you might find it useful to read the search system documentation and the list of search fields. These resources provide valuable insights into the various search functionalities and parameters that can be employed to refine your data extraction.
The Chart builder now allows you to open and customise most of the charts available at /emdb/statistics. If you see an edit icon, simply click on it to open the corresponding chart in the Chart builder. This feature provides you with the flexibility to modify and personalise the chart according to your specific requirements, enabling you to derive deeper insights from the data visualisation.

Figure 1: Edit button available in EMstats plots.
Fields
Archive
Select if your chart is going to be using data about EMDB or EMPIAR. (Note: the amount of available metadata is currently much greater for EMDB than for EMPIAR.)
Chart type
The Chart Builder currently supports four types of charts:
- Line: This chart type is best suited for visualising trends and changes over time. It can be used to illustrate how properties of one or more subsets of entries evolve over time.
Figure 2: Line chart example
- Bar: The bar chart is ideal for comparing different categories or groups. It provides a visual representation of the distribution and relative magnitudes of specific entries within each category.
Figure 3: Bar chart example
- Pie: The pie chart is a useful tool for illustrating proportions and percentages. It provides a concise visual representation of the distribution of a selected subset of entries among various categories. Pie charts can only have one data series, and the data categories are defined by the Data X parameter.
Figure 4: Pie chart example
- Area: Similar to a line chart, the area chart emphasises the cumulative size of subsets of entries over time.
Figure 5: Area chart example
Global filter
The optional global filter in the Chart Builder allows you to specify a search term that will be applied to the selected entries for the entire chart. This feature ensures that the resulting plot focuses on the specific data subset defined by the search term. For instance, suppose you wish to create a plot showcasing the number of entries related to Sars-Cov-2 per EM method. In that case, you can simply change one of the previous examples and set the following query within the global filter: `natural_source_ncbi_code:"2697049"`. This query narrows down the data to entries associated with the Sars-Cov-2 NCBI code, enabling the creation of a customised plot that visualises the desired information accurately.
Figure 6: Area chart with global filter
Data X
The Data X field determines the data that will be displayed on the X-axis or as categories in a pie chart. Within this field, there are three types of data X definitions:
Year:
The X-axis values in the chart correspond to the release year of the entries. By modifying the Data X settings, you can refine the previously created SARS-CoV-2 chart to display data specifically from the year 2019 and beyond.
Figure 7: Area chart with global filter and zoomed from 2019 to 2023.
Experimental metadata:
When selecting the option of "Experimental metadata" for the Data X field, you have the ability to choose one of the enumeration categories. The chosen category's elements will be displayed on the X-axis of the chart. For instance, you can set the experimental metadata category as an EM method to showcase the number of Sars-Cov-2 entries per each type of experiment.
Figure 8: Column chart with global filter displaying categorical metadata on x-axis
Custom queries:
You can define custom queries to specify a set of criteria that will be displayed on the x-axis of the chart. This allows you to customise the chart further according to your specific requirements. For example, you can modify the previous chart to include only the columns related to single-particle, subtomogram averaging, and tomography by using custom queries.
Figure 9: Column chart with global filter displaying specific metadata on x-axis
Custom queries are particularly important when creating pie charts since they can only have a single data series, and the slices of the pie are defined by the elements in the custom queries. We can modify the previous chart to be displayed as a pie chart. This allows for a concise visual representation of the distribution of the selected subset of entries among each experiment method.
Figure 10: Pie chart with custom metadata on slices
Data Y:
The Data Y field is used to set what information is going to be displayed along the Y-axis of your chart. For example, you can choose to display the number of entries, publications, or resolution on the Y-axis, depending on the nature of your analysis and the insights you seek to derive from the chart.
Data series:
This field defines the data series that will be displayed in your chart. A data series consists of three pieces of information: operator, query, and label. The available operators depend on the selection made in the Data Y field. If Data Y is a numeric variable, the operator can be average, minimum, maximum, or sum. On the other hand, if Data Y is a categorical variable, the operator can be the count of unique values or cumulative values. Additionally, you can apply an optional filter query for each data series. This is useful when comparing multiple classes of information, as demonstrated in the example below.
Figure 11: Chart composed by multiple data series to illustrate the 10 most common virus families in EMDB
Attributes
There are seven attributes that can be used to print, download, export and change the chart visualisation:

- Change how area and columns are displayed. There are three options: unstacked, stacked and stacked percent.
- Select to display the data series in a logarithmic or linear scale.
- Share the current chart. The resulting URL will be copied into the clipboard.
- Print the current chart.
- Download the chart image or data table.
- Full Screen mode.
- Extra options.
Publications:
Quick links
Recent Entries
(Show all)Structure of human 26S proteasome complexed with midnolin(1-111+337-468)
The structure of phycobilisome with a bicylindrical core from the cyanobacterium Synechococcus elongatus PCC 7942
The cryo-EM structure of PBS core from Synechococcus elongatus PCC 7942
The cryo-EM structure of PBS rod from synechococous elongatus PCC 7942
The structure of phycobilisome rod from Synechococcus elongatus PCC 7942
The cryo-EM structure of PBS from Synechococcus elongatus PCC 7942
The cryo-EM structure of PBS core from Synechococcus elongatus PCC 7942
The cryo-EM structure of PBS from Synechococcus elongatus PCC 7942
Structure of the Chlamydomonas reinhardtii chlororibosome with P-site tRNA
XBP1u-stalled RPL4 RNC in complex with NAC (locally refined on 40S head)
Cryo-EM structure of Dengue virus serotype2 US/BID-V594/2006 strain bound with J9 fab.
Helical Reconstruction of DENV2 THSTI/TRC/01 tubular particles bound with J9 fab
Structure of the Chlamydomonas reinhardtii chlororibosome with factor pY
Helical Reconstruction of DENV2 US/BID-V594/2006 tubular particles bound with J9 fab
XBP1u-stalled RPL4 RNC in complex with NAC (locally refined on 40S body)
Cryo-EM structure of Dengue virus serotype2 THSTI/TRC/01 strain bound with J9 fab
Structure of Cytochrome C6 bound Photosystem I from Chlamydomonas reinhardtii at 2.07 A resolution
Structure of Photosystem I from Chlamydomonas reinhardtii at 1.83 A resolution
RuvBL core from encounter state of SRCAP-nucleosome complex (focused refinement)
Cryo-EM model of E. coli aspartate transcarbamoylase in the T-state complexed with CP, CTP, and Mg2+
TRRAP lobe of the native human TIP60 complex, top region (focused refinement)
Cryo-EM structure of human SRCAP-nucleosome complex in the fully-engaged state (consensus map filtered by local resolution)
RuvBL core from fully-engaged state of SRCAP-nucleosome complex (focused refinement)
ATPase module from fully-engaged state of SRCAP-nucleosome complex (focused refinement)
Cryo-EM structure of human SRCAP-nucleosome complex in the partially-engaged state (consensus map filtered by local resolution)
Nucleosome from fully-engaged state of SRCAP-nucleosome complex (focused refinement)
ARP6-ZNHIT1 module from fully-engaged state of SRCAP-nucleosome complex (focused refinement)
Cryo-EM structure of human SRCAP complex in the unbound state (consensus map filtered by local resolution)
RuvBL core from pre-engaged state of SRCAP-nucleosome complex (focused refinement)
ATPase module from partially-engaged state of SRCAP-nucleosome complex (focused refinement)
Nucleosome from pre-engaged state of SRCAP-nucleosome complex (focused refinement)
ARP6-ZNHIT1 module from encounter state of SRCAP-nucleosome complex (focused refinement)
ARP6-ZNHIT1 module from pre-engaged state of SRCAP-nucleosome complex (focused refinement)
Cryo-EM structure of human SRCAP-nucleosome complex in the pre-engaged state (consensus map filtered by local resolution)
ARP6-ZNHIT1 module from unbound SRCAP complex (focused refinement)
RuvBL core from partially-engaged state of SRCAP-nucleosome complex (focused refinement)
ARP6-ZNHIT1 module from partially-engaged state of SRCAP-nucleosome complex (focused refinement)
Cryo-EM structure of human SRCAP-nucleosome complex in the encounter state (consensus map filtered by local resolution)
Nucleosome from partially-engaged state of SRCAP-nucleosome complex (focused refinement)
Nucleosome from encounter state of SRCAP-nucleosome complex (focused refinement)
ATPase module from encounter state of SRCAP-nucleosome complex (focused refinement)
RuvBL lobe of the native human TIP60 complex, HSA module (focused refinement)
Cryo-EM structure of the TRRAP lobe of the native human TIP60 complex (consensus map filtered by local resolution)
RuvBL lobe of the native human TIP60 complex, bottom RUVBL region (focused refinement)
RuvBL lobe of the native human TIP60 complex, top RUVBL region (focused refinement)
TRRAP lobe of the native human TIP60 complex, core region (focused refinement)
TRRAP lobe of the native human TIP60 complex, distal region (focused refinement)
TRRAP lobe of the native human TIP60 complex, bottom region (focused refinement)
Cryo-EM structure of the RuvBL lobe of the native human TIP60 complex (consensus map filtered by local resolution)
High-resolution cryo-EM structure of KdpFABC in the E1P state in lipid nanodisc
High-resolution cryo-EM structure of KdpFABC in the E1-ATP state in lipid nanodisc
High-resolution cryo-EM structure of KdpFABC in the E1 state in lipid nanodisc
High-resolution cryo-EM structure of KdpFABC in the E2P state in lipid nanodisc
High-resolution cryo-EM structure of KdpFABC in the E2 state in lipid nanodisc
CH35 gp41-FP macaque polyclonal Fab in complex with Q23-APEX-GT2 trimer
CH35 V1V2V3 and gp41-base macaque polyclonal Fabs in complex with Q23-APEX-GT2 trimer
Cryo-EM structure of V2 apex germline-targeting HIV Env trimer Q23-APEX-GT2
Cryo-EM structure of rhesus antibody CH70-Apex2.01 in complex with HIV Env trimer Q23-APEX-GT2
Cryo-EM structure of rhesus antibody CH42-Apex2.01 in complex with HIV Env trimer Q23-APEX-GT2
CH70 gp41-GH macaque polyclonal Fab in complex with Q23-APEX-GT2 trimer
Cryo-EM structure of rhesus antibody CI91-Apex1.01 in complex with HIV Env trimer Q23-APEX-GT2
Cryo-EM structure of rhesus antibody CH70-Apex1.01 in complex with HIV Env trimer Q23-APEX-GT2
Cryo-EM structure of rhesus antibody CH35-Apex1.08 in complex with HIV Env trimer Q23-APEX-GT2
CryoEM analysis of Phosphoglucose isomerase from P. aeruginosa reveals potential clinically relevant features
Zymogen ADAM17- iRhom1 Cytoplasmic Deletion (370) Complex Bound by the MEDI3622 Fab
Cryo-EM structure of rhesus antibody CH42-Apex1.01 in complex with HIV Env trimer Q23-APEX-GT2
Single Particle Cryo EM Analysis of a Ribosome Nascent Globin Complex
Cryo-EM structure of a pentameric RAD51-XRCC3-RAD51C-RAD51D-XRCC2 (51-X3CDX2) complex.
Cryo-EM structure of an octameric RAD51-XRCC3-RAD51C (RAD51-X3C) complex
Cryo-EM Structure of a RAD51 filament bound by ssDNA and the XRCC3-RAD51C-RAD51D-XRCC2 paralog complex
Cryo-EM structure of complex I on the bovine heart submitochondrial particles, closed
Cryo-EM structure of complex I on the bovine heart submitochondrial particles, open
Cryo-EM structure of FoF1-ATPase monomer state 3 on the bovine heart submitochondrial particles (FoF1-2)
Cryo-EM structure of FoF1-ATPase monomer state 1 on the bovine heart submitochondrial particles (FoF1-1)
Cryo-EM structure of complex III on the bovine heart submitochondrial particles, III-1
Cryo-EM structure of complex IV on the bovine heart submitochondrial particles, IV-B
Cryo-EM structure of complex IV on the bovine heart submitochondrial particles, IV-C
Cryo-EM structure of complex III on the bovine heart submitochondrial particles, III-2
Cryo-EM structure of Fo domain of FoF1-ATPase monomer state on the bovine heart submitochondrial particles
Cryo-EM structure of complex IV on the bovine heart submitochondrial particles, IV-A
Raw consensus map of Type II-A CRISPR integrase prespacer catching complex, State I
Cryo-EM structure of ATP-bound Oryza sativa MRP5 with E1424Q mutation
Cryo-EM structure of rice multidrug resistance protein 5 (MRP5) with InsP6 in state B
Cryo-EM structure of the human P2X3 receptor in the ATP-bound, desensitized state
Cryo-EM structure of Oryza sativa multidrug resistance protein 5 (MRP5)
Cryo-EM structure of rice multidrug resistance protein 5 (MRP5) with InsP6 in state A
Cryo-EM structure of the human P2X3 receptor in the ATP- and sivopixant-bound closed state
Cryo-EM structure of a tetrameric XRCC3-RAD51C-RAD51D-XRCC2 complex
70S global refined map of E.coli 70S ribosome complexed with P-site fMet-tRNAfMet and A-site S-beta(2)hydroxyBocK-tRNAPyl
Paclitaxel/GMPCPP-stabilized human alpha1A/beta3 S239C microtubule
Cryo-ET STA of immature HERV-K Gag with the Cc corrector and 60 eV energy filter slit width
CryoEM SPA of Rotavirus triple layer particles collected with Cc corrector and energy filter slit width of 20 eV
CryoEM SPA of Rotavirus triple layer particles collected with Cc corrector and without an energy filter slit
Cryo-ET STA of immature HERV-K Gag collected with Cc corrector and 20eV energy filter slit width
CryoEM SPA of Rotavirus triple layer particles collected with Cc corrector and energy filter slit width of 60 eV
in situ S. pombe hibernating ribosome after 7 days of glucose depletion
In situ Outer Mitochondrial Membrane Tethered Hibernating Ribosomes from S. pombe under glucose depletion
In situ Free Cytosolic Hibernating Ribosomes from S. pombe under glucose depletion
CryoEM structure of mu-opioid receptor - Gi protein complex bound to fluornitrazene (FNZ)
Zymogen ADAM17- iRhom1 Cytoplasmic Deletion (365) Complex Bound by the MEDI3622 Fab
Cryo EM Structure of GTP cyclohydrolase 1 (FolE) from Mycobacterium tuberculosis
Structure of human 26S proteasome complexed with midnolin, 19S proteasome with Ubl bound
apo Multidrug resistance-associated protein 2 in complex with AMP-PNP in rest state
Structure of human 26S proteasome complexed with midnolin, 19S proteasome with Ubl and Catch domain resolved
Multidrug resistance-associated protein 2 in complex with MK-571 and ATP
Cryo-EM structure of Full particle of prokaryotic dsRNA virus phiYY
Multidrug resistance-associated protein 2 in complex with AMP-PNP in active state
Substrate-free human 26S proteasome purified by midnolin, 20S proteasome, RPTs and RPN11 part
Structure of the tip region of the intial complex in bacterial flagellar filament assembly at 3.68 angstroms resolution, conformation 3.
Cryo-EM structure of cyanobacterial bicarbonate transporter CmpBCD
