EMD-56419

Single-particle
3.4 Å
EMD-56419
3D View Gallery
Deposition: 19/01/2026
Map released: 11/02/2026
Last modified: 18/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-56419

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9tyh summary report (pdf.gz) Map-9tyh FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of the MAP2K MEK1 in an active conformation in complex with its substrate MAPK ERK2

EMD-56419

Single-particle
3.4 Å
EMD-56419
3D View Gallery
Deposition: 19/01/2026
Map released: 11/02/2026
Last modified: 18/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Toxoplasma gondii ME49
Sample: Complex between the MAP2K MEK1 and its substrate MAPK ERK2
Fitted models: 9tyh

Deposition Authors: von Velsen J, Juyoux P, Bowler MW
Molecular basis of mitogen-activated protein kinase ERK2 activation by its upstream kinase MEK1.
von Velsen J, Juyoux P, Piasentin N, Fisher H, Lapouge K, Vadas O, Gervasio FL, Bowler MW
(2026) bioRxiv
PUBMED: 41648251
DOI: doi:10.64898/2026.01.19.700303
ISSN: 2692-8205
Grant Support: