EMD-70395
Ab1999 in complex with HIV-1 Env RC1
EMD-70395
Single-particle3.94 Å
Deposition: 28/04/2025Map released: 11/02/2026
Last modified: 11/03/2026
Sample Organism:
Macaca mulatta,
Human immunodeficiency virus 1,
Homo sapiens
Sample: Antibody Ab1999 Fab in complex with HIV-1 Env RC1
Fitted models: 9oed
Deposition Authors: Lin ZJ
,
Cui J,
Du J ,
Relano-Rodriguez I ,
Escolano A ,
Pallesen J
Sample: Antibody Ab1999 Fab in complex with HIV-1 Env RC1
Fitted models: 9oed
Deposition Authors: Lin ZJ
,
Cui J,
Du J ,
Relano-Rodriguez I ,
Escolano A ,
Pallesen J
Rapid elicitation of neutralizing Asn332-glycan-independent antibodies to the V3-glycan epitope of HIV-1 Env in nonhuman primates.
Relano-Rodriguez I ,
Du J ,
Lin ZJ ,
Kerwin M,
Tarquis-Medina M,
Urbano E,
Cui J,
Watkins M,
Lavine CL,
Zhao P ,
Habib R ,
Agostino C,
Ghosh S,
Park J,
Boroughs C,
Walsh AA,
Melo MB ,
Shukla N,
Shaw GM,
Hahn BH,
Irvine DJ ,
Wells L ,
Weiner DB ,
Seaman MS,
Kulp DW,
Veazey RS ,
Pallesen J ,
Escolano A
(2026) Nat Immunol , 27 , 586 - 599
,
Du J ,
Lin ZJ ,
Kerwin M,
Tarquis-Medina M,
Urbano E,
Cui J,
Watkins M,
Lavine CL,
Zhao P ,
Habib R ,
Agostino C,
Ghosh S,
Park J,
Boroughs C,
Walsh AA,
Melo MB ,
Shukla N,
Shaw GM,
Hahn BH,
Irvine DJ ,
Wells L ,
Weiner DB ,
Seaman MS,
Kulp DW,
Veazey RS ,
Pallesen J ,
Escolano A
(2026) Nat Immunol , 27 , 586 - 599
Grant Support:
- Bill & Melinda Gates Foundation: (United States)