EMD-46602

Single-particle
3.31 Å
EMD-46602
3D View Gallery
Deposition: 16/08/2024
Map released: 11/02/2026
Last modified: 18/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-46602

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9d74 summary report (pdf.gz) Map-9d74 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

CryoEM structure of anti-MHC-I Fab B1.23.2 complex with HLA-B44:05

EMD-46602

Single-particle
3.31 Å
EMD-46602
3D View Gallery
Deposition: 16/08/2024
Map released: 11/02/2026
Last modified: 18/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: Complex of Anti-human-mAb B1.23.2 Fab and MHC-I HLA-B44:05
Fitted models: 9d74

Deposition Authors: Jiang J , Natarajan K , Margulies DH , Lei H , Huang R
Structural mechanism of anti-MHC-I antibody blocking of inhibitory NK cell receptors in tumor immunity.
Jiang J , Panda AK, Natarajan K , Lei H , Sharma S, Boyd LF, Towler RR , Chempati S, Ahmad J, Morton AJ, Lang ZC, Sun Y, Sgourakis N , Meier-Schellersheim M , Huang RK, Shevach EM , Margulies DH
(2026) Commun Biol , 9
PUBMED: 41629525
DOI: doi:10.1038/s42003-026-09641-8
ISSN: 2399-3642