EMD-70117
KICSTOR-GATOR1 complex (SZT2 [1-1330], NPRL2, NPRL3, DEPDC5) focused refinement.
EMD-70117
Single-particle3.1 Å
Deposition: 09/04/2025Map released: 11/02/2026
Last modified: 01/04/2026
Sample Organism:
Homo sapiens
Sample: Binary complex of KICSTOR-GATOR1
Deposition Authors: Bayly-Jones C
,
Lupton CJ ,
Chang YG ,
Ellisdon AM
Sample: Binary complex of KICSTOR-GATOR1
Deposition Authors: Bayly-Jones C
,
Lupton CJ ,
Chang YG ,
Ellisdon AM
Structure of the lysosomal KICSTOR-GATOR1-SAMTOR nutrient-sensing supercomplex.
Lupton CJ ,
Bayly-Jones C ,
Dong S,
Lam T,
Luo W,
Jones GD,
Mastos C,
Frescher NJ,
Lim SS,
Keen AC,
Formosa LE ,
Venugopal H,
Chang YG ,
Halls ML,
Ellisdon AM
(2026) Cell , 189 , 1185 - 1200.e28
,
Bayly-Jones C ,
Dong S,
Lam T,
Luo W,
Jones GD,
Mastos C,
Frescher NJ,
Lim SS,
Keen AC,
Formosa LE ,
Venugopal H,
Chang YG ,
Halls ML,
Ellisdon AM
(2026) Cell , 189 , 1185 - 1200.e28
Grant Support:
- National Health and Medical Research Council (NHMRC, Australia): APP2036864 (Australia)
- Australian Research Council (ARC): DE240100992 (Australia)
- Other government: MCRF21036 (Australia)
- Australian Research Council (ARC): LE170100016 (Australia)