EMD-49520

Single-particle
3.59 Å
EMD-49520
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Deposition: 03/03/2025
Map released: 11/02/2026
Last modified: 11/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49520
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Focused refinement of the prefusion F glycoprotein ectodomain of Nipah virus in complex with DS90 nanobody

EMD-49520

Single-particle
3.59 Å
EMD-49520
3D View Gallery
Deposition: 03/03/2025
Map released: 11/02/2026
Last modified: 11/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Henipavirus nipahense
Sample: Prefusion F glycoprotein ectodomain of Nipah virus ectodomain in complex with DS90 nanobody

Deposition Authors: Low YS, Isaacs A, Modhiran N, Watterson D
A nanobody-based therapeutic targeting Nipah virus limits viral escape.
Isaacs A, Nieto GV, Zhang X, Modhiran N, Barr J, Thakur N, Low YS, Parry RH, Barnes JB, Jara R, Himelreichs J, Yao Y, Deride C, Barthou-Gatica B, Salinas-Rebolledo C, Ehrenfeld P, Hen JJ, Hayes N, Paramitha D, Morgan MS, McMillan CLD, Jones ML, Munro TP, Khromykh AA, Reading PC, Young PR, Chappell KJ, Shi Y, Bailey D, Marsh GA, Chiu S, Rojas-Fernandez A, Watterson D
(2025) Nat Struct Mol Biol , 32 , 1920 - 1931
PUBMED: 40629166
DOI: doi:10.1038/s41594-025-01598-2
ISSN: 1545-9985