Compressed conformation of nighttime state KaiC

Extended conformation of daytime state KaiC

Extended conformation of nighttime state KaiC

Nanosandwich composite of two RNA-DNA hybrid nanotriangles bound at a streptavidin core

The AAVrh.10-glycan complex

AAVrh.10:ADK8/9

AAVrh.10:HL2381

AAVrh.10:ADK8

AAVrh.10:HL2383

Cryo-EM structure of Patched in lipid nanodisc - the wildtype, 3.5 angstrom (re-processed with dataset of 7dzq)

Cryo-EM structure of Patched1 (V1084A mutant) in lipid nanodisc, 3.64 angstrom (reprocessed with the dataset of 7dzp)

20S+monoUb-CyclinB1-NT (S2)

20S proteasome (after post-processing)

20S proteasome incubated with monoUb-CyclinB1-NT (S0)

20S+monoUb-CyclinB1-NT (S1)

Cryo-EM structure of monomeric TTYH2

RACK1-S278E, 40S body masked from 80S rotated state, locally refined and filtered

RACK1-S278E, reconstruction from 40S particles (filtered according to local resolution)

RACK1-S278E, 60S masked from 80S rotated state, locally refined and filtered

RACK1-WT, 80S nonrotated consensus reconstruction

RACK1-WT, 40S head masked from 80S rotated state, locally refined and filtered

RACK1-WT, 80S rotated state, consensus reconstruction

RACK1-WT, 40S body masked from 80S rotated state, locally refined and filtered

RACK1-S278E, 80S non-rotated state, consensus reconstruction

RACK1-WT, 60S masked from 80S rotated state, locally refined and filtered

RACK1-S278E, 40S head masked from 80S rotated state, locally refined and filtered

RACK1-S278E 80S rotated state, consensus reconstruction

Cryo-EM structure of human p97-R191Q mutant bound to ADP.

Cryo-EM structure of human p97 bound to CB-5083 and ADP.

Cryo-EM structure of human p97-D592N mutant bound to ATPgS.

Cryo-EM structure of human p97-R155H mutant bound to ATPgS.

Cryo-EM structure of human p97-A232E mutant bound to ATPgS.

Cryo-EM structure of human p97 bound to CB-5083 and ATPgS.

Cryo-EM structure of human p97-R191Q mutant bound to ATPgS.

Cryo-EM structure of human p97-D592N mutant bound to ADP.

Cryo-EM structure of human p97-E470D mutant bound to ADP.

Cryo-EM structure of human p97-E470D mutant bound to ATPgS.

Cryo-EM structure of human p97-R155H mutant bound to ADP.

Cryo-EM structure of human p97-A232E mutant bound to ADP

Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody C118 (State 1)

Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody C118 (State 2)

structure of a channel

Cryo-EM structure of ABCG1 E242Q mutant with ATP and cholesteryl hemisuccinate bound

Cryo-EM structure of the Rhodospirillum rubrum RC-LH1 complex

Structure of PPPA bound human ACAT2

Cryo-EM structure of the human SSU processome - RRP12-BYST focused map

Cryo-EM structure of the human SSU processome, state post-A1 - HEATR1 focused map

Cryo-EM structure of the human SSU processome, state post-A1 - RPS19-AROS focused map

Cryo-EM structure of the human SSU processome - NOC4L-NOP14 focused map

Cryo-EM structure of the human SSU processome, state post-A1 - H44 focused map

Cryo-EM structure of the human SSU processome, state pre-A1 - NEP1 focused map

Cryo-EM structure of the human SSU processome, state pre-A1 - UTPA focused map

Cryo-EM structure of the human SSU processome, state post-A1 - UTPA focused map

Cryo-EM structure of the human SSU processome, state post-A1 - UTPC-central focused map

Cryo-EM structure of the human SSU processome, state post-A1 - NOL11 focused map

Cryo-EM structure of the human SSU processome, state pre-A1 - NAT10-NOL10 focused map

Cryo-EM structure of the human SSU processome, state post-A1 - Core focused map

Cryo-EM structure of the human SSU processome, state pre-A1 - UTPC-Central focused map

Cryo-EM structure of the human SSU processome, state post-A1 - UTP6 focused map

Cryo-EM structure of the human SSU processome, state post-A1 - UTPC focused map

Cryo-EM structure of the human SSU processome, state post-A1 - probable MYBBP1A focused map

Cryo-EM structure of the human SSU processome, state post-A1 - UTP20 focused map

Cryo-EM structure of the human SSU processome, state post-A1 - DHX37 focused map

Cryo-EM structure of RTX-bound full-length TRPV1 in C2 state

Cryo-EM structure of minimal TRPV1 with RTX bound in C2 state

Cryo-EM structure of minimal TRPV1 with 2 bound RTX in opposite pockets

Cryo-EM structure of minimal TRPV1 with 1 partially bound RTX

Cryo-EM structure of minimal TRPV1 with 3 bound RTX and 1 perturbed PI

Cryo-EM structure of minimal TRPV1 with RTX bound in C1 state

Cryo-EM structure of minimal TRPV1 with 2 bound RTX in adjacent pockets

Cryo-EM structure of minimal TRPV1 with 4 partially bound RTX

Cryo-EM structure of minimal TRPV1 with 1 perturbed PI

core proteins of mature t7

LPS-treated full bacteriophage T7

Structural changes in bacteriophage T7 upon receptor-induced genome ejection

core-portal-tail complex

Symmety-mismatch Reconstruction of Mature T7

portal-tail complex of mature T7

portal-tail complex of LPS-treated full bacteriophage T7

LPS-treated empty bacteriophage T7

Cryo-EM structure of the human SSU processome, state post-A1

Cryo-EM structure of the human SSU processome, state post-A1 - raw maps

Cryo-EM structure of the human SSU processome, state pre-A1

Cryo-EM structure of the human SSU processome, state pre-A1 - raw maps

Cryo-EM structure of the human SSU processome, state pre-A1*

Asymmetric structure of the uncleaved full-length HIV-1 envelope glycoprotein trimer in state U1

Asymmetric structure of the uncleaved full-length HIV-1 envelope glycoprotein trimer in state U2

Coupling of N7-methyltransferase and 3'-5' exoribonuclease with SARS-CoV-2 polymerase reveals mechanisms for capping and proofreading

Cryo-EM structure of zebrafish TRPM5 in the presence of 1 mM EDTA

Cryo-EM structure of human islet amyloid polypeptide (hIAPP, or amylin) fibrils seeded by patient extracted fibrils, polymorph 1

Cryo-EM structure of human islet amyloid polypeptide (hIAPP, or amylin) fibrils seeded by patient extracted fibrils, polymorph 3

Cryo-EM structure of human islet amyloid polypeptide (hIAPP, or amylin) fibrils seeded by patient extracted fibrils, polymorph 2

Cryo-EM structure of human islet amyloid polypeptide (hIAPP, or amylin) fibrils seeded by patient extracted fibrils, polymorph 4

Structure of human 20S proteasome with bound MPI-5

Structure of Plasmodium falciparum 20S proteasome with bound MPI-5

Structure of Plasmodium falciparum 20S proteasome with bound bortezomib

Cryo-EM structure of the cytochrome bd oxidase from M. tuberculosis in presence of AD3-11 at 2.8 A resolution

Cryo-EM structure of the cytochrome bd oxidase from M. tuberculosis in presence of Aurachin D at 3.3 A resolution

the complex of inactive CaSR and NB2D11

Structural insights into the activation of human calcium-sensing receptor

Cryo-EM structure of the cytochrome bd oxidase from M. tuberculosis at 2.5 A resolution

Human p97 in complex with Npl4/Ufd1 and polyubiquitinated Ub-Eos in the presence of ATP and sub-stoichiometric NMS-873 (Class 1)

ASCT2 in the presence of the inhibitor ERA-21 in the outward-open conformation.

ASCT2 in the presence of the inhibitor Lc-BPE in the outward-open conformation.

Cryo-EM structure of DkTx-bound minimal TRPV1 at the singly-bound state

Cryo-EM structure of RTX-bound full-length TRPV1 at pH 5.5

Cryo-EM structure of full-length TRPV1 at pH6c state

cryo-EM structure of unliganded minimal TRPV1

cryo-EM structure of DkTx-bound minimal TRPV1 in partial open state

Cryo-EM structure of full-length TRPV1 at pH6a state

cryo-EM structure of RTX-bound minimal TRPV1 with NMDG at state a

Cryo-EM structure of RTX-bound full-length TRPV1 in C1 state

cryo-EM structure of DkTx-bound minimal TRPV1 in open state

Cryo-EM structure of RTX-bound full-length TRPV1 in O1 state

cryo-EM structure of DkTx-bound minimal TRPV1 at the pre-bound state

Cryo-EM structure of unliganded full-length TRPV1 at neutral pH

cryo-EM structure of RTX-bound minimal TRPV1 with NMDG at state c

Cryo-EM structure of full-length TRPV1 at pH6b state

Cryo-EM structure of DkTx/RTX-bound full-length TRPV1

cryo-EM structure of RTX-bound minimal TRPV1 with NMDG at state b

Cryo-EM structure of DkTx-bound minimal TRPV1 at the pre-open state

Spike protein trimer

apo state of class C GPCR

intermediate state of class C GPCR

CryoEM structure of a trehalose monomycolate transporter in TMM lipid nanodiscs (form II)

CryoEM structure of a trehalose monomycolate transporter in lipid nanodiscs

CryoEM structure of a trehalose monomycolate transporter in lipid nanodiscs

CryoEM structure of a trehalose monomycolate transporter in lipid nanodiscs

The C1b projection within the the ciliary central apparatus from the cryo-electron tomography and subtomographic average of isolated Chlamydomonas fap246 axonemes

The C1b projection within the the ciliary central apparatus from the cryo-electron tomography and subtomographic average of isolated Chlamydomonas fap42 axonemes

The C1b projection within the ciliary central apparatus from the cryo-electron tomography and subtomographic average of isolated Chlamydomonas wild type axonemes

Cryo-EM structure of rabbit RyR1 in the presence of AMP-PCP in nanodisc

Cryo-EM structure of rabbit RyR1 in the presence of Mg2+ and AMP-PCP in nanodisc

Focused cryo-EM map of rabbit RyR1 central and transmembrane domains in the presence of AMP-PCP in nanodisc

Focused cryo-EM map of rabbit RyR1 central and transmembrane domains in the presence of Mg2+ and AMP-PCP in nanodisc

CryoEM structure of a CRISPR-Cas complex

SpCas9 delta4CE Ternary Complex