Negative stain map of A/New York/631/1996 H3N2 HA in complex with 97_F7 IgG

Negative stain map of A/New York/631/1996 H3N2 HA in complex with 33_C08 IgG

Negative stain map of A/New York/631/1996 H3N2 HA in complex with 18_D11 IgG

Negative stain map of A/California/07/2009 H1N1 HA in complex with 97_F7 IgG

Negative stain map of A/California/07/2009 H1N1 HA in complex with 49_C09 IgG

Negative stain map of A/California/07/2009 H1N1 HA in complex with 33_C02 IgG

Negative stain map of A/New York/631/1996 H3N2 HA in complex with 88_B4 IgG

ArsB from L. ferriphilum in presence of arsenite (reconstruction I)

Negative stain map of A/California/07/2009 H1N1 HA in complex with 3_H2 IgG

Cryo-EM hexamer map of the resting EcDRT3 complex

Composite cryo-EM map of the resting EcDRT3 complex

Composite cryo-EM map of the elongating EcDRT3 complex

Teichoic acid flippase TacF from Streptococcus pneumoniae

Cryo-EM map of Drt3a and ncRNA in the elongating EcDRT3 complex

Cryo-EM protomer map of the elongating EcDRT3 complex

Map of the Drt3a-ncRNA subcomplex in the EcDRT3 complex with ddATP and dCTP

Cryo-EM map of the EcDRT3 hexameric complex with ddATP and dCTP.

Cryo-EM map of Drt3a and ncRNA in the resting EcDRT3 complex

Cryo-EM protomer map of the EcDRT3 complex with ddATP and dCTP.

Cryo-EM protomer map of the resting EcDRT3 complex

Cryo-EM hexamer map of the elongating EcDRT3 complex

Cryo-EM structure of E. coli RNA polymerase in complex with EP1

The head-arm region of HBx-Smc5/6 ubiquitination complex

Cryo-EM structure of E. coli RNA polymerase in complex with VP1

The hinge-arm region of HBx-Smc5/6 ubiquitination complex

HBx-Smc5/6 ubiquitination complex

Cryo-EM structure of Bacillus halodurans ComEC

Giraffe KIF5A motor domain in nucleotide free state bound to microtubule

Cryo-EM structure of Shewanella putrefaciens ComEC in complex with ssDNA

The head region of HBx-Smc5/6 ubiquitination complex

Alcohol Oxidase Mod2p from Ogataea methanolica

Alcohol Oxidase Mod1p from Ogataea methanolica

Cryo-EM structure of Shewanella decolorationis ComEC

Cryo-EM structure of Shewanella putrefaciens ComEC in complex with dsDNA

Cryo-EM structure of E. coli RNA polymerase in complex with PP1

Structure of PfENT1 in complex with GSK3

Epitope and functional classification of human neutralizing antibodies against SFTSV Gn

Epitope and functional classification of human neutralizing antibodies against SFTSV Gn

Epitope and functional classification of human neutralizing antibodies against SFTSV Gn

Structure of PfENT1(S143C,S382C) with inosine

Structure of PfENT1(T144C,K375C,N60R,Q266R) with inosine- outward-facing state

Structure of PfENT1(T144C,K375C) with inosine

TRiC from bovine flagella, focused refinement on one-ring

TRiC purified from bovine sperm flagella, concensus map

TRiC_HDAC1_close_state

TRiC purified from bovine flagellar, focused refinement on E-domain

Structure of PfENT1(S143C,S382C)-occluded state

TRiC_HDAC3_PDCD5 local map

DENV2 non-structural protein 1 (NS1) Stable Tetramer complexed with Heparin

DENV2 non-structural protein 1 (NS1) Stable Tetramer Conformation 1

DENV2 non-structural protein 1 (NS1) with C-terminal mVenus Conformation 2

DENV2 non-structural protein 1 (NS1) Dimer

80S rabbit ribosome in complex with alpha-1-antitrypsin nascent chain on the P-site tRNA

DENV2 non-structural protein 1 (NS1) Loose Tetramer Conformation 1

DENV2 non-structural protein 1 (NS1) Stable Tetramer Conformation 2

DENV2 non-structural protein 1 (NS1) with C-terminal mVenus Conformation 1

DENV2 non-structural protein 1 (NS1) Loose Tetramer Conformation 2

Stabilized complex of Chlamydia trachomatic efector CT622 in complex with human WD40 domain of ATG16L1

DENV2 non-structural protein 1 (NS1) with C-terminal mVenus fusion

B/Brisbane/60/2008 HA in complex with FV2DP1-1B

B/Hubei-Wujiagang/158/2009 HA in complex with BO-6B

B/Hubei-Wujiagang/158/2009 HA in complex with FV2DP1-1B

B/Brisbane/60/2008 HA in complex with BO-6B

Structure of substrate-engaged single-cap human proteasome in state EA1

B/Phuket/3073/2013-like HA in complex with BP-1A

B/Brisbane/60/2008 HA in complex with BP-1A

Structure of substrate-engaged human 26S proteasome RP-CP subcomplex in state ED2.1

Structure of substrate-engaged human 26S proteasome RP-CP subcomplex in state ED1.2

Structure of substrate-engaged double-cap human proteasome in state EA1-EA1

Structure of substrate-engaged single-cap human proteasome in state EB

Structure of substrate-engaged single-cap human proteasome in state EC1

Structure of substrate-engaged human 26S proteasome RP-CP subcomplex in state ED2.3

Structure of substrate-engaged single-cap human proteasome in state EC2

Structure of substrate-engaged single-cap human proteasome in state ED0

Consensus map of human 26S proteasome in EA1-EA1 double-cap state (EMD-62090), also serving as focused map on the 20S core particle region via pseudo-single cap extraction strategy with C2/D2 symmetry

A focused map of the human 26S proteasome in the EA1-EA1 double-cap state (EMD-62090), focusing on the 19S regulatory particle region.

Structure of substrate-engaged single-cap human proteasome in state ED1

Structure of substrate-engaged single-cap human proteasome in state ED2

A focused map of the human 26S proteasome in the EA1-EA1 double-cap state (EMD-62090), focusing on the 19S regulatory particle region.

Structure of substrate-engaged human 26S proteasome RP-CP subcomplex in state ED2.2

Structure of substrate-engaged single-cap human proteasome in state EA2

Structure of substrate-engaged human 26S proteasome RP-CP subcomplex in state ED1.3

Human vault protein - primed conformation

Human vault protein - local refinement of the waist - primed conformation

Cryo-EM structure of the tubular mastigoneme (the central tube) from golden algae 2.17 angstrom resolution

Microtubule obtained by in situ cryo-electron tomography (cryo-ET) and subtomogram averaging of mouse brain tissue

Ribosomes on the endoplasmic reticulum membrane obtained by in situ cryo-electron tomography (cryo-ET) and subtomogram averaging of mouse brain tissue

Cytosolic ribosomes obtained by in situ cryo-electron tomography (cryo-ET) and subtomogram averaging of mouse brain tissue

Structure of substrate-engaged 26S proteasome RP-CP subcomplex in state EA1.2

Structure of substrate-engaged human 26S proteasome RP-CP subcomplex in state EB.1

Structure of substrate-engaged human 26S proteasome RP-CP subcomplex in state EA2.3

Structure of substrate-engaged human 26S proteasome RP-CP subcomplex in state EC2

Structure of substrate-engaged human 26S proteasome RP-CP subcomplex in state EB.3

Structure of substrate-engaged human 26S proteasome RP-CP subcomplex in state EA1.1

Structure of substrate-engaged human 26S proteasome RP-CP subcomplex in state EA1.0

Structure of substrate-engaged human 26S proteasome RP-CP subcomplex in state EA2.2

Structure of substrate-engaged 26S proteasome RP-CP subcomplex in state EB.2

Structure of substrate-engaged human 26S proteasome RP-CP subcomplex in state ED0.1

Structure of substrate-engaged human 26S proteasome RP-CP subcomplex in state EC1

Structure of substrate-engaged human 26S proteasome RP-CP subcomplex in state EA2.1

Structure of substrate-engaged human 26S proteasome RP-CP subcomplex in state ED1.1

Structure of substrate-engaged human 26S proteasome RP-CP subcomplex in state ED0.3

Structure of substrate-engaged human 26S proteasome RP-CP subcomplex in state ED0.2

Yeast V-ATPase bound to Rtc5p, rotary state 2

Focused map of CXCL9-CXCR3

Focused map of Gi-scFv16 (components of CXCL9-CXCR3-Gi-scFv16)

Consensus map of CXCL9-CXCR3-Gi-scFv16

Composite map of CXCL10-CXCR3-Gi-scFv16

Composite map of CXCL9-CXCR3-Gi-scFv16

Composite map of CXCL11-CXCR3-Gi-scFv16

consensus map of CXCL11-CXCR3-Gi-scFv16

Focused map of Gi-scFv16 (components of CXCL10-CXCR3-Gi-scFv16)

consensus map of CXCL10-CXCR3-Gi-scFv16

Focused map of CXCL10-CXCR3 (components of CXCL10-CXCR3-Gi-scFv16)

Focused map of CXCL11-CXCR3 (components of CXCL11-CXCR3-Gi-scFv16)

Focused map of Gi_scFv16 (components of CXCL11-CXCR3-Gi-scFv16)

MvhAGD-focused map of the mobile arm under state 2 substate b of M. marburgensis

HdrBC-focused map of the mobile arm under state 2 substate b of M. marburgensis

Cryo-EM structure of plant resistance protein NRC2 dimer bound to nematode effector SPRYSEC-15

Focused map of the FmdF dimer unit of the Mvh-Hdr-Fmd complex of M. marburgensis

Focused map of the FmdABCFG(2) unit of the Mvh-Hdr-Fmd complex of M. marburgensis

Focused map of the FmdABCFG(1) unit of the Mvh-Hdr-Fmd complex of M. marburgensis

Focused map of the C-terminus of the MvhB subunit of the Mvh-Hdr-Fmd complex of M. marburgensis

Focused map of the MvhB subunit of the Mvh-Hdr-Fmd complex of M. marburgensis

HdrA-focused map of the mobile arm under state 2 substate b of M. marburgensis

Consensus map of the mobile arm under state 2 substate a of M. marburgensis

HdrA-focused map of the mobile arm under state 2 substate a of M. marburgensis

HdrBC-focused map of the mobile arm under state 1 substate b of M. marburgensis

HdrA-focused map of the mobile arm under state 1 substate a of M. marburgensis

MvhAGD-focused map of the mobile arm under state 1 substate b of M. marburgensis

Consensus map of the mobile arm under state 2 substate b of M. marburgensis

MvhAGD-focused map of the mobile arm under state 1 substate a of M. marburgensis

HdrA-focused map of the mobile arm under state 1 substate b of M. marburgensis

MvhAGD-focused map of the mobile arm under state 2 substate a of M. marburgensis

Consensus map of the mobile arm under state 1 substate b of M. marburgensis

HdrBC-focused map of the mobile arm under state 1 substate a of M. marburgensis

HdrBC-focused map of the mobile arm under state 2 substate a of M. marburgensis

Structure of the MvhAGD-HdrABC dimer of M. marburgensis under state 1 substate a (composite structure)

Consensus map of the mobile arm under state 1 substate a of M. marburgensis

Structure of the MvhAGD-HdrABC dimer of M. marburgensis under state 1 substate b (composite structure)

Structure of the MvhAGD-HdrABC dimer of M. marburgensis under state 2 substate a (composite structure)

Human vault protein - local refinement of the waist - committed conformation

Structure of the MvhAGD-HdrABC dimer of M. marburgensis under state 2 substate b (composite structure)

Structure of the Mvh-Hdr-Fmd complex of Methanothermobacter marburgensis (composite structure)

Consensus low resolution map of the flavin-bifurcating CO2-fixing Mvh-Hdr-Fmd supercomplex from Methanothermobacter marburgensis

Atomic resolution cryoEM structure of HPV16 bound to heparin

Global map of six VRC35 Fabs and three MEDI8852 Fabs bound to influenza H3N2 Victoria 2011 hemaglutinin

Cryo-EM structure of NVL bound the the MM927 inhibitor

Focused refinement of PP2Ac repeat 1 of the FBXO42-CCDC6-PP2Ac degradasome

Consensus refinement of the FBXO42-CCDC6-PP2Ac degradasome

Cryo-EM structure of human VCP/p97-R89W mutant bound to ATPgammaS

Cryo-EM structure of human VCP/p97-R89W mutant bound to ADP

Cryo-EM structure of human VCP/p97-T122P mutant bound to ATPgammaS

Cryo-EM structure of human VCP/p97-G128D mutant bound to ATPgS

Cryo-EM structure of human VCP/p97-G128D mutant bound to ADP

Cryo-EM structure of human VCP/p97-T122P mutant bound to ADP

Cryo-EM structure of human VCP/p97-G156D mutant bound to ADP

Cryo-EM structure of human VCP/p97-R89W mutant bound to CB-5083

Structure of human lymphoid-specific helicase HELLS in its auto-inhibitory state

Cryo-EM structure of human VCP/p97-G156D mutant bound to ATPgammaS

Structure of human lymphoid-specific helicase HELLS in its auto-inhibitory state

Structure of human lymphoid-specific helicase HELLS in its auto-inhibitory state

Focussed refinement map of ATPase lobe 2 of human lymphoid-specific helicase HELLS

Structure of human lymphoid-specific helicase HELLS in its auto-inhibitory state

SthK closed state at low temperature, cAMP-bound in DOPC nanodiscs

Closed Eco-ePEC: Cryo-EM structure of Eco RNAP his-elemental paused elongation complex with a closed active site (closed TL, SI3 and RH-FL)

N49P7-FR Fab in complex with BG505 MD39 SOSIP and RM20A3 Fab

Open1 Eco-ePEC: Cryo-EM structure of Eco RNAP his-elemental paused elongation complex with an open active site (open TL, SI3 and RH-FL)

ssRNA phage PRR1 virion with 3' gRNA

CA-SP1 immature lattice assembled in vitro with inhibitor lenacapavir (dialyzed to 50nM)

Gag CA-SP1 immature lattice bound with Lenacapavir from enveloped virus like particles

eN49P7-FRv1-23 Fab in complex with BG505 MD39 SOSIP and RM20A3 Fab

Open2 Eco-ePEC: Cryo-EM structure of Eco RNAP his-elemental paused elongation complex with an open active site (open TL, SI3 and RH-FL)

Open3 Eco-ePEC: Cryo-EM structure of Eco RNAP his-elemental paused elongation complex with an open active site (open TL, SI3 and RH-FL)

Cryo-EM map of the E. coli clamp loader DnaX-complex loading beta-clamp onto 1-nt gapped DNA in state 2 conformer 1 with sharply bent DNA

Cryo-EM map of the E. coli clamp loader DnaX-complex loading beta-clamp onto 1-nt gapped DNA in state 1 conformer 1 with flexibly bound DNA at the shoulder

Cryo-EM map of the E. coli clamp loader DnaX-complex loading beta-clamp onto 1-nt gapped DNA in state 1 conformer 2 with flexibly bound DNA at the shoulder

Cryo-EM map of the E. coli clamp loader DnaX-complex loading beta-clamp onto 1-nt gapped DNA in state 1 conformer 3 with disordered DNA at the shoulder

Cryo-EM map of the E. coli clamp loader DnaX-complex alone

Cryo-EM map of the E. coli clamp loader DnaX-complex loading beta-clamp onto 1-nt gapped DNA in state 2 conformer 2 with less bent DNA

Cryo-EM map of the E. coli clamp loader DnaX-complex loading beta-clamp onto 10-nt gapped DNA in state 2 conformer 1 with fully open clamp and unsettled DNA

Cryo-EM map of the E. coli clamp loader DnaX-complex loading beta-clamp onto 10-nt gapped DNA in state 2 conformer 3 with partially closed clamp

Cryo-EM map of the E. coli clamp loader DnaX-complex loading beta-clamp onto 10-nt gapped DNA in state 2 conformer 2 with fully open clamp and settled DNA

Cryo-EM map of the E. coli clamp loader DnaX-complex loading beta-clamp onto 10-nt gapped DNA in state 1 the DNA recognition state

Cryo-EM map of the E. coli clamp loader DnaX-complex loading beta-clamp onto 10-nt gapped DNA in state 2 conformer 5 with fully closed clamp

Cryo-EM map of the E. coli clamp loader DnaX-complex loading beta-clamp onto 10-nt gapped DNA in state 2 conformer 6 with fully closed clamp

Cryo-EM map of the E. coli clamp loader DnaX-complex loading beta-clamp onto 10-nt gapped DNA in state 2 conformer 4 with fully closed clamp

High-resolution cryo-EM structure of Maltose Binding Protein

Structure of a membrane protein

High-resolution cryo-EM structure of human Polo-like kinase 1 in complex with onvansertib

Cryo-EM structure of CXCR4 complexed with agonist SDVX1

Cryo-EM structure of AsCas12a in complex with crDNA and RNA target

Cryo-EM strucutre of CXCR4 complexed with agonist SDV1a

EV-A71 (genotype C4) in complex with 16-3-10B Fab

EV-A71 (genotype B5) in complex with 16-2-2D Fab

EV-A71 (genotype B5) in complex with 16-3-3C Fab

EV-A71 (genotype B5) in complex with 17-2-12A Fab

EV-A71 (genotype B5) in complex with 17-2-2B Fab

EV-A71 (genotype B5) in complex with 16-2-8C Fab

EV-A71 (genotype B5) empty particle in complex with 16-3-3C Fab

EV-A71 (genotype C4) in complex with 16-2-11B Fab

EV-A71 (genotype B2) in complex with 16-2-9D Fab

EV-A71 (genotype B5) in complex with 17-1-12A Fab

EV-A71 (genotype B2) in complex with 34-1-6D Fab

EV-A71 (genotype B5) in complex with 16-3-4D Fab

EV-A71 (genotype B2) in complex with 16-2-12D Fab

The cryo-EM structure of Zea mays GLN1

Bovine Flagellar TRiC

3D reconstruction of Themis:Grb2:ProMacrobody256 after 3D classification (Class 3)

CryoEM map of Themis bound to ProMacrobody 256

3D reconstruction of Themis:ProMacrobody256 after 3D classification (Class 2)

CryoEM structure of the Themis:Grb2 complex with bound ProMacrobody 256

3D reconstruction of Themis:Grb2:ProMacrobody256 after 3D classification (Class 4)

3D reconstruction of Themis:ProMacrobody256 after 3D classification (Class 1)

3D reconstruction of Themis:Grb2:ProMacrobody256 after 3D classification (Class 1)

CryoEM structure of the Themis:Grb2 complex with bound ProMacrobody 256, local refinement

3D reconstruction of Themis:Grb2:ProMacrobody256 after 3D classification (Class 2)

high-affinity choline transporter in DDM with Na+

F-actin in complex with USP54 M1 actin binding motif

Leishmania mexicana secreted acid phosphatase at pH 5.6

Leishmania mexicana secreted acid phosphatase

high-affinity choline transporter in DDM with Na+ and choline

Cryo-EM structure of alphaM/beta2 headpiece complex without alphaM I-domain - the consensus map from alphaM/beta2:C3d-anti-CR3-Nb headpiece complex

In-cell structure of H1-bound nucleosome

In-cell structure of core nucleosome

39-mer half of the human vault protein

Mouse Ribosome RPS15 (uS19) P131S rotated-2 PRE state

In-cell structure of stacking H1-bound nucleosomes

In-cell structure of open-linker H1-bound nucleosome

Flat structure of mPiezo1 in plasma membrane vesicles

Cryo-electron tomography of an A549 cell infected with influenza A/WSN/33 virus

Curved structure of mPiezo1 in plasma membrane vesicles

Cryo-electron tomography of an A549 cell infected with influenza A/WSN/33 virus

RNA polymerase open complex on T7A1 promoter (RPo)

De novo initial transcribing RNA polymerase on T7A1 promoter (weak downstream)

De novo initial transcribing RNA polymerase with 2-mer RNA and bound CTP / Michaelis complex (RPitc2+CTP)

De novo initial transcribing RNA polymerase with 5-mer RNA AUCUA (RPitc5b)

De novo initial transcribing RNA polymerase with pretranslocated 3-mer RNA / product complex (RPitc3)

De novo initial transcribing RNA polymerase with 9-mer RNA (RPitc9)

De novo initial transcribing RNA polymerase with sigma 70 region 1.1 bound (RPitc-s70_1.1)

De novo initial transcribing RNA polymerase on T7A1 promoter (empty channel)

de novo initial transcribing RNA polymerase with 5-mer RNA CCAUC (RPitc5a)

Structure of the two-pore domain, outwardly rectifying potassium (TOK1) from Candida albicans, overall structure

Structure of the two-pore domain, outwardly rectifying potassium (TOK1) from Candida albicans, Down conformation

Structure of the two-pore domain, outwardly rectifying potassium (TOK1) from Candida albicans, Up conformation

Cryo-EM structure of the TNF-alpha-Ozoralizumab (OZR)-HSA complex

TNF-alpha in complex with the TNF-alpha inhibitor Ozoralizumab (OZR)

Cryo-EM structure of SARS CoV2 S protein with stabilising mutations

Cryo-EM structure of Dengue virus serotype2 THSTI/TRC/01 strain bound with D14.F25.SO2 fab

Structural Analysis of a Plant Glycoside Hydrolase Family 116 Glucosyl Ceramidase by Cryogenic Electron Microscopy (Cryo-EM)

Helical Reconstruction of DENV2 US/BID-V594/2006 tubular particles bound with D14.F25.S02 fab

split variant of Aquifex aeolicus lumazine synthase-derived nucleocapsid variant NC-4

Cryo-EM structure of Heyndrickxia coagulans beta-galactosidase

The TMD structure of native mouse AMPAR with 2 TARPs 2 CNIHs

The TMD structure of native mouse AMPAR with 4 TARPs

Cryo-EM structure of the CbCash filament bound to cA4

The LBD-TMD structure of native mouse AMPAR with 4 TARPs

Cryo-EM Structure of Nipah Virus Polymerase in complex with GL22

Cryo-EM Structure of Nipah Virus Polymerase in complex with ERDRP-0519

Cryo-EM Structure of Nipah Virus Polymerase in complex with G671

Cryo-EM Structure of Measles Virus Polymerase in complex with ERDRP-0519

DHIK wk12 + Rhesus Macaque polyFab

Cryo-EM Structure of Peste Des Petits Ruminants Virus Polymerase in complex with ERDRP-0519

Cryo-EM structure of apo CbCash dodecamer

The LBD-TMD structure of native mouse AMPAR with 2 TARPs 2 CNIHs

cryoEM structure of CbCash filament with cA4 and tRNA Ile CAU

The LBD-TMD structure of native mouse AMPAR with 3 TARPs 1 CNIH

The TMD structure of native mouse AMPAR with 3 TARPs 1 CNIH

Cryo-EM structure of Measles Virus L Protein bound by Phosphoprotein Tetramer

Cryo-EM structure of mouse heavy-chain apoferritin on continuous carbon from 300 kV Titan Krios

Cryo-EM structure of Peste Des Petits Ruminants Virus L Protein bound by Phosphoprotein Tetramer

Cryo-EM structure of mouse heavy-chain apoferritin on continuous carbon from 200 kV Glacios

SARS-CoV-2 Omicron BA.1 spike protein in complex with a self-assembling trivalent nanobody Tr67

The TMD structure of native mouse AMPAR with 2 TARPs 2 CNIHs and PRRT1/SynDIG4

The LBD-TMD structure of native mouse AMPAR with 2 TARPs

The LBD-TMD structure of native mouse AMPAR with 2 TARPs 2 CNIHs and PRRT1/SynDIG4

The LBD-TMD structure of native mouse AMPAR with 3 TARPs 1 CNIH and PRRT1/SynDIG4

The LBD-TMD structure of native mouse AMPAR with 3 TARPs

Ca2+-bound MthK WT in lipid nanodiscs composed of 14:1PC (75%) and POPG (25%)

Ca2+-bound MthK WT in lipid nanodiscs composed of 22:1PC (75%) and POPG (25%)

CryoEM structure of the 41-kDa Thermus thermophilus HSP70 nucleotide-binding domain at 3.79 Angstrom resolution reveals the bound AMP-PNP and large-scale domain rearrangement

Structure of DabA2B2 complex under 0.1M bicarbonate

Structure of DabA2B2 complex solved under ambient condition

Structure of DabA2B2 complex under 17 mM CO2

Negative stain map of A/California/07/2009 H1N1 HA in complex with 33_C08 IgG

Negative stain map of A/California/07/2009 H1N1 HA in complex with 88_B4 IgG

Negative stain map of A/California/07/2009 H1N1 HA in complex with 18_D11 IgG

ArsB from L. ferriphilum in presence of arsenite (reconstruction II)