EMD-52787

Single-particle
3.2 Å
EMD-52787
3D View Gallery
Deposition: 11/02/2025
Map released: 29/04/2026
Last modified: 03/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-52787
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9iaz summary report (pdf.gz) Map and 9iaz FULL report (pdf.gz)
EMICSS annotations (xml)

CryoEM structure of the Themis:Grb2 complex with bound ProMacrobody 256, local refinement

EMD-52787

Single-particle
3.2 Å
EMD-52787
3D View Gallery
Deposition: 11/02/2025
Map released: 29/04/2026
Last modified: 03/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Escherichia coli
Sample: Themis-Grb2 complex bound to ProMacrobody 256
Fitted models: 9iaz

Deposition Authors: Clancy DM, Felix J, Bloch Y, Savvides SN
Structural and mechanistic insights into the constitutive Themis-Grb2 complex in T cell signalling.
Clancy DM, Sanz-Sanjuan A, Gilis E, Tougaard P, Velghe I, Van Droogenbroeck Y, Felix J, Bloch Y, Cuadrado AF, Merceron R, Schenck S, Vandenabeele P, Brunner JD, Taghon T, Elewaut D, Savvides SN
(2026) Nat Commun
PUBMED: 42161968
DOI: doi:10.1038/s41467-026-73359-8
ISSN: 2041-1723