EMD-71307
N49P7-FR Fab in complex with BG505 MD39 SOSIP and RM20A3 Fab
EMD-71307
Single-particle2.7 Å
Deposition: 18/06/2025Map released: 29/04/2026
Last modified: 29/04/2026
Sample Organism:
Human immunodeficiency virus 1,
Macaca mulatta,
Homo sapiens
Sample: N49P7-FR Fab in complex with BG505 MD39 SOSIP and RM20A3 Fab
Fitted models: 9p6e
Deposition Authors: Phulera S, Ozorowski G, Ward AB
Sample: N49P7-FR Fab in complex with BG505 MD39 SOSIP and RM20A3 Fab
Fitted models: 9p6e
Deposition Authors: Phulera S, Ozorowski G, Ward AB
Engineering HIV antibodies with enhanced breadth and potency of neutralization through multistate affinity maturation.
Kedzior M ,
Phulera S,
Fernandez-Quintero ML,
Loeffler JR,
Joyce C,
Woehl J,
Abbasi A,
Karimi M,
Aslanabadi A,
Hojabri M,
Zareidoodeji R,
Atkinson B,
Burgos EFP,
Heredia A,
Saye-Francisco K,
Tran Q,
Kim Y,
Acosta-Puente F,
Shahin L,
Zhou A,
Altman PX ,
Felbinger NR,
Pierce BG,
Sok D,
Seaman MS,
Burton DR,
DeVico AL,
Ward AB ,
Ozorowski G,
Sajadi MM,
Jardine JG
(2025) bioRxiv
,
Phulera S,
Fernandez-Quintero ML,
Loeffler JR,
Joyce C,
Woehl J,
Abbasi A,
Karimi M,
Aslanabadi A,
Hojabri M,
Zareidoodeji R,
Atkinson B,
Burgos EFP,
Heredia A,
Saye-Francisco K,
Tran Q,
Kim Y,
Acosta-Puente F,
Shahin L,
Zhou A,
Altman PX ,
Felbinger NR,
Pierce BG,
Sok D,
Seaman MS,
Burton DR,
DeVico AL,
Ward AB ,
Ozorowski G,
Sajadi MM,
Jardine JG
(2025) bioRxiv
Grant Support: