EMD-53451

Single-particle
3.7 Å
EMD-53451
3D View Gallery
Deposition: 17/04/2025
Map released: 29/04/2026
Last modified: 29/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-53451
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80S rabbit ribosome in complex with alpha-1-antitrypsin nascent chain on the P-site tRNA

EMD-53451

Single-particle
3.7 Å
EMD-53451
3D View Gallery
Deposition: 17/04/2025
Map released: 29/04/2026
Last modified: 29/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Oryctolagus cuniculus
Sample: 80S ribosome with stalled nascent chain of Alpha-1-antitrypsin

Deposition Authors: Plessa E, Mitropoulou AN, Christodoulou J, Cabrita LD

Visualisation of translating ribosomes reveals the earliest steps of protein misfolding in human disease
Plessa E, Chu LP, Hornby CR, Streit JO, Chan SHS, Mitropoulou AN, Irving JA, Lomas DA, Christodoulou J, Cabrita LD
To Be Published
Grant Support: