EMD-68245

Single-particle
3.17 Å
EMD-68245
3D View Gallery
Deposition: 08/01/2026
Map released: 29/04/2026
Last modified: 13/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-68245

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-22fn summary report (pdf.gz) Map-22fn FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of AsCas12a in complex with crDNA and RNA target

EMD-68245

Single-particle
3.17 Å
EMD-68245
3D View Gallery
Deposition: 08/01/2026
Map released: 29/04/2026
Last modified: 13/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Acidaminococcus sp. BV3L6, synthetic construct
Sample: Cas12a
Fitted models: 22fn

Deposition Authors: Lam WH, Wu X, Hsing IM, Zhai Y
DNA-guided CRISPR-Cas12a effectors for programmable RNA recognition and cleavage.
Wu X, Lam WH, Zhao Z, Cao Y, Lin H, Feng X, Zhai Y, Hsing IM
(2026) Nat Biotechnol
PUBMED: 42067668
DOI: doi:10.1038/s41587-026-03120-5
ISSN: 1087-0156
ASTM: NABIF9