EMD-72390

Single-particle
2.61 Å
EMD-72390 Deposition: 28/08/2025
Map released: 29/04/2026
Last modified: 29/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-72390

Cryo-EM structure of human VCP/p97-G156D mutant bound to ADP

EMD-72390

Single-particle
2.61 Å
EMD-72390 Deposition: 28/08/2025
Map released: 29/04/2026
Last modified: 29/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: VCP/p97 G156D mutant bound to ADP
Fitted models: 9y0b

Deposition Authors: Lehman A , Ahmed S, Mohajeri A , Yang GX, Berezuk AM, Mannar D , Cholak S, Tuttle KS, Bennett JT , Magno JA, Hannibal M, Kovacevic G, Kuburovic V, Lewis MES, Moldovan O, Nelson Z, Raskin S, Vandersteen AM, Roach JC, Subramaniam S, Patel MS
Mutations in VCP cause Adams-Oliver syndrome with or without pulmonary hypertension.
PUBMED: 41979051
DOI: doi:10.1016/j.gim.2026.102579
ISSN: 1530-0366