EMD-72388

Single-particle
2.78 Å
EMD-72388
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Deposition: 28/08/2025
Map released: 29/04/2026
Last modified: 29/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-72388
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9y08 summary report (pdf.gz) Map and 9y08 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of human VCP/p97-G128D mutant bound to ADP

EMD-72388

Single-particle
2.78 Å
EMD-72388
3D View Gallery
Deposition: 28/08/2025
Map released: 29/04/2026
Last modified: 29/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: VCP/p97 G128D mutant bound to ADP
Fitted models: 9y08

Deposition Authors: Lehman A, Ahmed S, Mohajeri A, Yang GX, Berezuk AM, Mannar D, Cholak S, Tuttle KS, Bennett JT, Magno JA, Hannibal M, Kovacevic G, Kuburovic V, Lewis MES, Moldovan O, Nelson Z, Raskin S, Vandersteen AM, Roach JC, Subramaniam S, Patel MS
Mutations in VCP cause Adams-Oliver syndrome with or without pulmonary hypertension.
Lehman A, Ahmed S, Mohajeri A, Berezuk AM, Mannar D, Cholak S, Tuttle KS, Bennett JT, Aparecida Magno J, Hannibal M, Kovacevic G, Kuburovic V, Suzanne Lewis ME, Moldovan O, Nelson Z, Raskin S, Vandersteen AM, Roach JC, Subramaniam S, Patel MS
(2026) Genet Med , 102579 - 102579
PUBMED: 41979051
DOI: doi:10.1016/j.gim.2026.102579
ISSN: 1530-0366