EMD-52604

Single-particle
3.8 Å
EMD-52604
3D View Gallery
Deposition: 23/01/2025
Map released: 29/04/2026
Last modified: 29/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-52604

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

3D reconstruction of Themis:Grb2:ProMacrobody256 after 3D classification (Class 1)

EMD-52604

Single-particle
3.8 Å
EMD-52604
3D View Gallery
Deposition: 23/01/2025
Map released: 29/04/2026
Last modified: 29/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: Themis-Grb2 complex bound to ProMacrobody 256

Deposition Authors: Clancy DM , Felix J, Bloch Y, Savvides SN
Structural and mechanistic insights into the constitutive Themis-Grb2 complex in T cell signalling.
Clancy DM , Sanz-Sanjuan A , Gilis E, Tougaard P, Velghe I , Van Droogenbroeck Y , Felix J, Bloch Y, Cuadrado AF , Merceron R, Schenck S , Vandenabeele P , Brunner JD , Taghon T , Elewaut D , Savvides SN
(2026) Nat Commun , 17
PUBMED: 42161968
DOI: doi:10.1038/s41467-026-73359-8
ISSN: 2041-1723