CAPRI: Critical Assessment of PRediction of Interactions

The CAPRI round 37 is in collaboration with 12th CASP session and will take place between May 1 and August 2016

Members of both the CASP and CAPRI communities will be invited to model the interfaces of protein hetero-complexes, homo-multimers and domain-domain
interactions in appropriate CASP12 targets.

Description of the CASP12 experiment can be found at: http://predictioncenter.org/casp12/index.cgi

As in 2014, the number or type of targets that will be made available for this round are currently unknown, as targets are being submitted to CASP piecemeal
during the entire duration of the CASP12 session. Decision on targets designated for CAPRI docking and scoring predictions (only a subset of the CASP12
targets prediction is expected to represent appropriate CAPRI targets) will be made by CAPRI MC members (Shoshana Wodak, Sameer Velankar, and Marc Lensink).
Information on these targets and submission deadlines (for servers, dockers and scorer) will be provided on the CAPRI website.

Registration: CAPRI participants wishing to take part in this CAPRI prediction round are invited to register for the entire round in advance. CAPRI registration
for Round 37 will be open starting May 4, and the first targets will be announced on Mon May 9. We also encourage CAPRI participants to register with the
CASP12 session, which is already open. When registering with CASP, participants should click the radio button "Do you want to receive an e-mail when a target
is designated as CAPRI?" In this case they will be receiving an automatic message each time a new CAPRI target is designated.

Upon receiving this message participants should consult the CAPRI site for additional target information and for the timelines for submission of server models,
docking models, uploading of models and the scoring submissions. Participants registered for Round 37 with CAPRI should submit models only to the CAPRI website.
Not to both!

All the submitted models of homo- and hetero- complexes will be evaluated by the CAPRI evaluation team, as usual. The possibility of applying additional
evaluation procedures by the CASP independent team will be examined at a meeting mid June in Rome, to which the CAPRI assessment team will be invited. These
additional procedures are likely to apply only to the prediction of domain-domain interactions in multi-domain proteins. Any suggestions from the CASP
assessment team for additional evaluation measures to be applied to predicted complexes, will first be examined by the CAPRI MC in consultations with the
CAPRI community, before they are accepted as part of the official CAPRI assessment procedure.

Documentation and Targets Round 37

• Download Target information
• Upload Opens 9th May 2016
• Upload of interface residue predictions opens 5th July 2016

• Participants
• Management Group
• Prediction formats

SCORERS

Scorers can download the server set of submissions from
http://cb.iri.univ-lille1.fr/capri/ using the same login user/pass as distributed for Capri round37. Full details and deadlines are given on this site.

Email Problems or Queries to Sameer Velankar