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CAPRI: Critical Assessment of PRediction of Interactions

Community wide experiment on the comparative evaluation of protein-protein docking for structure prediction

Hosted By EMBL/EBI-PDBe Group

Round 29

Round 29 ID mapping from group number to Accessor Number for Target 65
Round 29 ID mapping from group number to Accessor Number for Target 66
Round 29 ID mapping from group number to Accessor Number for Target 67

NOTE The Coordinates are not yet available for download

T65 result summary
T66 result summary
T67 result summary

Target 65

T65 shows two protein-peptide copies in the asymmetric unit, with identical peptide binding sites. The longer peptide (6-residue for BE, vs 4-residue for AD) seems to be stabilized by crystal contacts.

Results T65 interface A:D - click here to see the results
Results T65 interface B:E - click here to see the results
Full results:
Clash threshold 38.93
average 7.56
std dev 15.69


T65.ADT65.BE
Nr groups 43 43
High Accuracy (***) 0 ( 0) 0 ( 0)
Medium (**) 0 ( 0) 0 ( 0)
Acceptable (*) 1 ( 1) 2 ( 1)
Incorrect 317 (36) 293 (33)
Clashes 11 ( 2) 11 ( 2)
Low ID 27 ( 6) 50 ( 7)
Total 356 (39) 356 (39)


Target 66

T66 shows three complexes in the asymmetric unit, with basically identical peptide binding sites. One of the complexes (BD) shows a 5-residue peptide, the other only 3-residue. Crystal contacts do not play a role here.

Results T66 interface A:C - click here to see the results
Results T66 interface B:D - click here to see the results
Results T66 interface E:F - click here to see the results
Full results:
Clash threshold 52.24
average 10.00
std dev 21.12


T66.ACT66.BDT66.EF
Nr groups 40 40 40
High Accuracy (***) 0 ( 0) 0 ( 0) 0 ( 0)
Medium (**) 0 ( 0) 0 ( 0) 2 ( 1)
Acceptable (*) 7 ( 5) 3 ( 1) 13 ( 9)
Incorrect 299 (36) 276 (34)293 (34)
Clashes 17 ( 3) 17 ( 3) 17 ( 3)
Low ID 17 ( 2) 46 ( 5) 17 ( 2)
Total 342 (37) 342 (37) 342 (37)


Target 67

Results T67 - click here to see the results
Results T67 PPSY - using only the center four residues PPSY (click here to see the results)
Full results:
Clash threshold 22.08
average 5.69
std dev 8.20


T67.PPSY- Predictor T67- Predictor
Nr groups 39 39
High Accuracy (***) 9 ( 2) 0 ( 0)
Medium (**) 50 ( 12) 23 ( 6)
Acceptable (*) 126 ( 24) 87 ( 19)
Incorrect 150 (25) 223 (31)
Clashes 16 ( 5) 16 ( 5)
Low ID 0 ( 0) 2 ( 2)
Total 351 (38) 351 (38)

Numbers in parentheses refer to the number of different source groups producing these models (ie z scorer groups recognize y out of x uploader groups)



ROUND 29 Timeline

Round 29 will have following targets :
Target 65-67 : protein-peptide complexes

  • 18th Nov 2013 - Registration opens for Round 29
  • 29th Nov 2013 - Round 29 opens - Prediction of targets 65-67 (protein-peptide complexes)
  • 15th Dec 2013 - Deadline for submitting models for target 65 (a protein-peptide complex)
  • 20th Dec 2013 - Deadline for submitting models for targets 66-67 (protein-peptide complexes)


Documentation and Targets Round 29

  • Participants
  • Management Group
  • Prediction formats
  • Download Opens 29th Nov 2013
  • Upload Opens 29th Nov 2013

  • Entries

  • Current submissions

  • Email Problems or Queries to Sameer Velankar

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