Cryo-EM structure of 70S ribosome bound to EF-Tu imaged in a cell lysate

Human UHRF1 bound to a mononucleosome with a hemimethylation site in the linker DNA.

Cryo-EM structure of large ribosomal subunit (class B1) imaged in a cell lysate

Cryo-EM structure of large ribosomal subunit (class B2) imaged in a cell lysate

Cryo-EM structure of 30S ribosome in a closed conformation with tRNA bound imaged in a cell lysate

Cryo-EM structure of large ribosomal subunit (class A2) imaged in a cell lysate

Cryo-EM structure of 70S ribosome in the hybrid state (A/P*, P/E) imaged in a cell lysate

Cryo-EM structure of large ribosomal subunit (class C1) imaged in a cell lysate

Cryo-EM structure of large ribosomal subunit (class A1) imaged in a cell lysate

Cryo-EM structure of large ribosomal subunit (class 3) imaged in a cell lysate

Cryo-EM structure of 30S ribosome in a H44 inactive-dislodged state imaged in a cell lysate

Cryo-EM structure of large ribosomal subunit (class 5) imaged in a cell lysate

Cryo-EM structure of 30S ribosome in a H44 active state imaged in a cell lysate

Cryo-EM structure of 50S ribosome (class I) imaged in a cell lysate

Cryo-EM structure of 30S ribosome in a H44 inactive-unresolved state imaged in a cell lysate

Cryo-EM structure of large ribosomal subunit (class 2) imaged in a cell lysate

Cryo-EM structure of 30S ribosome with tRNA bound in an open conformation imaged in a cell lysate

Cryo-EM structure of large ribosomal subunit (class 4) imaged in a cell lysate

Cryo-EM structure of large ribosomal subunit (class 6) imaged in a cell lysate

Cryo-EM structure of the human P2X2 receptor in the apo closed state

Cryo-EM structure of the human P2X3 receptor in the camlipixant-bound inhibited state

Cryo-EM structure of the human P2X2/3 heteromer receptor bound to AF-219

Cryo-EM structure of the human P2X2/3 heteromer receptor - class 2 (2:1)

Cryo-EM structure of the human P2X2 receptor in the ATP-bound desensitised state

Cryo-EM structure of the human P2X2/3 heteromer receptor - class 1 (1:2)

The structure of Nav1.7 with veratridine standing near the IFM motif (site I)

Cryo-EM structure of the human P2X2 receptor in the ATP-bound open state

Wild-type alpha-synuclein fibril - Type 3-2

Wild-type alpha-synuclein fibril - Type 1

Prefusion stabilized spike glycoprotein of equine coronavirus.

Prefusion stabilized spike glycoprotein of human coronavirus OC43.

SPP1 Procapid I in cellula

Wild-type alpha-synuclein fibril - Type 3-1

Apoferritin from equine spleen, recovered from the synchrotron with 1 MGy X-ray dose

Apoferritin from equine spleen, recovered from the synchrotron with 0 MGy X-ray dose

Wild-type alpha-synuclein fibril - Type 5

Apoferritin from equine spleen, recovered from the synchrotron with 100 MGy X-ray dose

Wild-type alpha-synuclein fibril - Type 4

Cryo-EM structure of the extracellular domain of DC-SIGN

A53T alpha-synuclein fibril - Type 1

A53T alpha-synuclein fibril - Type 2

Structure of a membrane-bound inositol phosphorylceramide synthase and ceramide complex

Pointed end of Cofilin-2 Bound F-actin, Focused Refinement on Terminal Pointed End Actins

Two CAP-1 bound to the pointed end of cofilin F-actin

One CAP-1 Bound to the Pointed End of F-actin, Actin Local Refinement

Capping protein bound to the barbed end of F-actin, Barbed end local refinement

One CAP-1 Bound to the Pointed End of F-actin, HFD Local Refinement

Two CAP-1 Bound to the Pointed End of F-actin, Consensus Map

One CAP-1 Bound to the Pointed End of Cofilin F-actin, PE local map

Two CAP-1 bound to the pointed end of cofilin F-actin, actin local refinement

Structure of a membrane-bound inositol phosphorylceramide synthase and Aureobasidin A complex

Two CAP-1 Bound to the Pointed End of F-actin, Actin Local Refinement

Pointed end of Cofilin-2 Bound F-actin, Focused Refinement on Actin Filament

One CAP-1 Bound to the Pointed End of Cofilin F-actin, Actin local refinement

One CAP-1 Bound to the Pointed End of F-actin, Consensus Map

Two CAP-1 bound to the pointed end of cofilin F-actin, pointed end local refinement

Pointed end of Cofilin-2 Bound F-actin, Consensus Map

Two CAP-1 Bound to the Pointed End of F-actin, CAP1 HFD Local Refinement

Structural Insights into HIV-1 Vif-Mediated Ubiquitination and Degradation of APOBEC3H

Structure of human HER2 in complex with EPS226 Fab

13 protofilament P. falciparum paclitaxel stabilised GDP microtubule

Structure of human HER2 in complex with EPS232 Fab

15 protofilament P. falciparum GMPCPP microtubule

Structural Insights into HIV-1 Vif-Mediated Ubiquitination and Degradation of APOBEC3H

Polyclonal immune complex of Fab from serum of animal 1 at week 35 binding H1 HA

Polyclonal immune complex of Fab from serum of animal 1 at week 23 binding H1 HA

Polyclonal immune complex of Fab from serum of animal 6 at week 33 binding H1 HA

Cryo-EM of NBD-L4pY filament at 0.4 mM concentration

Polyclonal immune complex of Fab from serum of animal 4 at week 35 binding H1 HA

Polyclonal immune complex of Fab from serum of animal 5 at week 35 binding H1 HA

Computationally optimized broadly reactive influenza B hemagglutinin BC2 bound by antibodies #46 and #3978

Computationally optimized broadly reactive influenza B hemagglutinin BC2 bound by antibody #3978

Polyclonal immune complex of Fab from serum of animal 4 at week 23 binding H1 HA

Cryo-EM of NBD-L4pY nanofibers at 1.25mM concentration

Cryo-EM structure of Serendipita indica sulfate transporter SiSulT in Apo state

Polyclonal immune complex of Fab from serum of animal 6 at week 23 binding H1 HA

Cryo-EM of NBD-L4pY filament at 5mM concentration

cryo-EM structure of Serendipita indica sulfate transporter SiSulT in sulphate bound state

Polyclonal immune complex of Fab from serum of animal 6 at week 35 binding H1 HA

Computationally optimized broadly reactive influenza B hemagglutinin BC2 bound by antibodies #46 and #3978

Polyclonal immune complex of Fab from serum of animal 2 at week 35 binding H1 HA

Polyclonal immune complex of Fab from serum of animal 4 at week 33 binding H1 HA

Cryo-EM structure of Serendipita indica sulfate transporter SiSulT in oxlate bound state

Computationally optimized broadly reactive influenza B hemagglutinin BC2 bound by antibody #46

SARS-CoV-2 S2 in complex with polyclonal Fab-B_Donor3

SARS-CoV-2 S2 in complex with polyclonal Fab_Donor2

SARS-CoV-2 S2 in complex with polyclonal Fab_Donor1

SARS-CoV-2 S2 in complex with polyclonal Fab-B_Donor8

Stabilized SARS-CoV-2 S2 apo

S305I Frontotemporal Lobar Degeneration (FTLD) type I tau filament

SARS-CoV-2 S2 in complex with COV2-2509

S305I Frontotemporal Lobar Degeneration (FTLD) type II tau filament

SARS-CoV-2 spike S2 subunit in complex with polyclonal Fabs (Apex-B epitope)

SARS-CoV-2 spike S2 subunit in complex with polyclonal Fabs (Apex-A epitope)

Tetrameric complexes of the Borna disease virus 1 nucleoprotein arranged in a parallel configuration

S-shaped octameric complex of the Borna disease virus 1 nucleoprotein

Heptameric complex of the Borna disease virus 1 nucleoprotein bound to RNA (mutant Arg341Ala)

Tetrameric complex of the Borna disease virus 1 nucleoprotein (mutant Arg341Ala)

Triangular complex of Borna disease virus 1 nucleoprotein with 12 subunits

Hexameric complex of the Borna disease virus 1 nucleoprotein bound to RNA (mutant Arg341Ala)

Tetrameric complexes of the Borna disease virus 1 nucleoprotein (mutant Arg341Ala) in an antiparallel configuration

S-shaped nonameric complex of Borna disease virus 1 nucleoprotein

Hexameric oval ring-like complex of Borna disease virus 1 nucleoprotein

Tetrameric complex (3D class 1) of the Borna disease virus 1 nucleoprotein

Pentameric complex of the Borna disease virus 1 nucleoprotein

Tetrameric complex (3D class 2) of the Borna disease virus 1 nucleoprotein

Octameric ring-like complex of the Borna disease virus 1 nucleoprotein bound to RNA

Hexameric flat ring-like complex of the Borna disease virus 1 nucleoprotein

Asymmetric tetrameric complex of the Borna disease virus 1 nucleoprotein (mutant Arg341Ala)

Triangular complex of the Borna disease virus 1 nucleoprotein with 13 subunits

Heptameric ring-like complex of the Borna disease virus 1 nucleoprotein bound to RNA

Cryo-EM structure of SARS-CoV-2 PT Spike Protein complex with a potent broad-spectrum macrocyclic peptide inhibitor 6L3-3P11K

Hexameric oval ring-like complex of Borna disease virus 1 nucleoprotein with central extra density

Cryo-EM structure of TasH-tigRNA-gap dsDNA complex

Cryo-EM structure of TasH-tigRNA complex

Cryo-EM structure of TasH-tigRNA (5G)-dsDNA complex

Cryo-EM structure of TasH-tigRNA-dsDNA complex

Cryo-EM structure of TasH-tigRNA-ssDNA complex

Hexameric ring-like complex of the Borna disease virus 1 nucleoprotein bound to RNA

Hexameric flat ring-like complex of the Borna disease virus 1 nucleoprotein (mutant Lys164Ala)

Heptameric ring-like complex of the Borna disease virus 1 nucleoprotein (mutant Lys164Ala)

Tetrameric complexes of the Borna disease virus 1 nucleoprotein are arranged in an antiparallel configuration

Pentameric complex of Borna disease virus 1 nucleoprotein (mutant Lys164Ala)

Tetrameric complex of the Borna disease virus 1 nucleoprotein (mutant Lys164Ala)

Hexameric ring-like complex of the Borna disease virus 1 nucleoprotein (mutant Lys164Ala)

Heptameric flat ring-like complex of the Borna disease virus 1 nucleoprotein (mutant Lys164Ala)

Triangular hexameric complex of the Borna disease virus 1 nucleoprotein (mutant Lys164Ala)

Tetrameric complexes of the Borna disease virus 1 nucleoprotein (mutant Lys164Ala) in an antiparallel configuration

Structure of the Bacterial Ribosome with human tRNA Lys(mcm5s2U34) and mRNA(AAG)

S-shaped octameric complex of the Borna disease virus 1 nucleoprotein (mutant Lys164Ala)

Hexameric oval ring-like complex of the Borna disease virus 1 nucleoprotein (mutant Lys164Ala)

Structure of the Bacterial Ribosome with human tRNA Lys(mcm5h2U34) and mRNA(AAG)

Structure of the Bacterial Ribosome with human tRNA Lys(mcm5h2U34) and mRNA(AAA)

Structure of the Bacterial Ribosome with human tRNA Lys(mcm5s2U34) and mRNA(AAA)

Cryo-EM structure of TasH-pre-tigRNA-dsDNA complex

A LINC complex lattice in the nuclear envelope of ejaculated human sperm

mouse hippocampal CA1-sr synapse tomogram: CA1-sr dataset 2

D3 prohead 1 - icosahedral reconstruction

Penton focused D3 virion capsid

Icosahedral D3 expanded capsid

Penton focused expanded D3 capsid

D3 Virion icos

Penton focused prohead 1

D3 prohead 1

Penton focused D3 prohead 2

LolCDE in complex with SMT-738_2

LolCDE in complex with SMT-738_1

channel B complex with 2

channel A complex with 1

Plant chloroplast dicarboxylate transporter AtDiT1

Plant chloroplast dicarboxylate transporter AtDiT2.1 bound with malate

Plant chloroplast dicarboxylate transporter AtDiT1 bound with 2-OG

channel C complex with 3

Plant chloroplast dicarboxylate transporter AtDiT2.1 bound with Glu

Plant chloroplast dicarboxylate transporter AtDiT1 bound with OAA

channel D complex with 4

Plant chloroplast dicarboxylate transporter AtDiT2.1

ATP-bound wild type Wzm-Wzt from Mycobacterium abscessus in LMNG

Influenza A/H7N9 polymerase in complex with a 70-mer RNA template, in stalled elongation.

ADP-bound wild type Wzm-Wzt from Mycobacterium abscessus in LMNG

ADP-bound wild type Wzm-Wzt from Mycobacterium abscessus in nanodiscs

ATP-bound wild type Wzm-Wzt from Mycobacterium abscessus in nanodiscs

Nucleotide-free wild type Wzm-Wzt from Mycobacterium abscessus in LMNG

ATP-bound E178Q Wzm-Wzt from Mycobacterium abscessus in LMNG

Influenza A/H7N9 polymerase in complex with a 70-mer template in stalled elongation with backtracking and stem.

Cryo-EM structure of LH1-RC from Rhodovulum sulfidophilum

ATP-bound E178Q Wzm-Wzt from Mycobacterium abscessus in nanodiscs

Nucleotide-free wild type Wzm-Wzt from Mycobacterium abscessus in nanodiscs

The Traptamer with 2'-Fluoro-modified pyrimidines (FY RNA)

Adeno-Associated Virus 6-M2, AAV6-M2

ArsB from L. ferriphilum in inward-facing state (parallel dimer)

ArsB from L. ferriphilum bound to antimonite in inward-facing state (antiparallel dimer)

ArsB from L. ferriphilum in inward-facing state (antiparallel dimer)

ArsB from L. ferriphilum bound to arsenite in inward-facing state (parallel dimer)

Cryo-EM structure of the type I pilus from Escherichia Coli and the surrounding water network

Cryo-EM map of SARS-CoV-2 BA.2.75 Spike Protein complex with macrocyclic peptide 6L3 (All RBDs up)

Cryo-EM structure of the maize CER6-GL2 complex (inactive C222A mutant) in the presence of 28:0 CoA

Cryo-EM map of SARS-CoV-2 BA.2.75 Spike Protein complex with a macrocyclic peptide 6L3-3P11K (Two RBDs up)

Cryo-EM map of SARS-CoV-2 PT Spike Protein,Three RBDs down

Cryo-EM map of SARS-CoV-2 BA.2.75 Spike Protein (Three RBDs down)

Cryo-EM structure of SARS-CoV-2 BA.2.75 Spike Protein complex with a potent broad-spectrum macrocyclic peptide inhibitor 6L3-3P11K

Structure of LAT4 in the apo state

The cryo-EM structure of in situ amplified (ISA) alpha-synuclein fibrils from DLB homogenate

Structure of the flagellar filament in short-length at 3.02 angstroms resolution

The cryo-EM structure of in situ amplified (ISA) alpha-synuclein fibrils from PD homogenate

Cryo-EM structure of PTH1R(V2RC)-beta-arrestin1 complex

Structure of LAT4 in complex with Phe

Cryo-EM structure of PTH1R-beta-arrestin1 complex in state 2

Structure of LAT4 in complex with digitonin

Ice-free ESIBD structure of GroEL

Cryo-EM structure of NMHase in complex with DHU

Cryo-EM structure of DICER/26S-UG complex in dicing state

Cryo-EM structure of DICER/26S-GU complex in dicing state

Cryo-EM structure of DICER-D991G-H992G/26S-GU complex in dicing state

Cryo-EM structure of DICER with pre-mir-517a-GU in pre-dicing state

MexBYB-Ka asymmetry

Cryo-EM structure of the spermidine-bound zTAAR13c-Gs complex

MexBYB-apo asymmetry

MexBYB-Ka symmetry-like

Cryo-EM structure of DICER with pre-mir-517a-GU in dicing state

MexBYB-apo symmetry-like

Cryo-EM structure of the histamine-bound zTAAR13a-Gs complex

Hexamer Msp1 from S.cerevisiae (with a catalytic dead mutation) in complex with an unknown peptide substrate

Cryo-EM structure of the agmatine-bound zTAAR13e-Gs complex

Hexamer Msp1 from S.cerevisiae (with a catalytic dead mutation) in complex with an unknown peptide substrate

Hexamer Msp1 from S.cerevisiae (with a catalytic dead mutation) in complex with an unknown peptide substrate

Focused map on Arm 2 of the human LRP2 ectodomain

Focused map of the lower body part of the human LRP2 ectodomain

Assembly intermediate of human mitochondrial ribosome small subunit bound to METTL15, RBFA, and mtIF2 (State M2.1)

Focused map of the head domain of the human LRP2 ectodomain

Consensus map prior to focused analysis of the human LRP2 ectodomain

Structure of Teneurin-Like Protein (TLP)

Focused map on the Arm 1 of the human LRP2 ectodomain

Focused mask on the upper body of the human LRP2 ectodomain

Focused map on head of the human LRP2 in complex with LRPAP1

Assembly intermediate of human mitochondrial ribosome small subunit bound to METTL15 and RBFA (Inward conformation) (State M2)

Focused map on the arm 2 of the human LRP2 in complex with LRPAP1

Consensus initial map of the human LRP2 in complex with LRPAP1

Focused map on the lower body of the human LRP2 in complex with LRPAP1

Focused map of the upper body of the human LRP2 in complex with LRPAP1

Focused map on the Arm 1 of the human LRP2 in complex with LRPAP1

Further focused map on the Arm 1 of the human LRP2 in complex with LRPAP1

Focused map on the arm 2 and RAPd3 copy of the human LRP2 in complex with LRPAP1

CryoEM structure of the human LRP2 receptor ectodomain in complex with LRPAP1

Focused map on additional extra density at the level of the Arm 2 of the human LRP2 in complex with LRPAP1

CryoEM structure of apo Toxin B (TcdB) from Clostridioides difficile in the closed CROP state

CryoEM structure of Toxin B (TcdB) from clostridioides difficile complexed with methyl cholate

CryoEM structure of Toxin B (TcdB) from clostridioides difficile complexed with taurochenodeoxycholic acid (TCDCA)

Cryo-ET of FIB-milled synapse region between CD19+ NALM6 leukemia cells and T-cells expressing 8H8 CD19 CAR construct (sample3)

N1 neuraminidase of influenza A/Vietnam/1203/2004 H5N1 in complex with four FNI9 Fab molecules

CryoEM structure of apo Toxin B (TcdB) from Clostridioides difficile in the open CROP state

30S focus refined map of E.coli 70S ribosome complexed with P-site fMet-tRNAfMet and A-site R-beta(2)hydroxyBocK-tRNAPyl

50S focus refined map of E.coli 70S ribosome complexed with P-site fMet-tRNAfMet and A-site R-beta(2)hydroxyBocK-tRNAPyl

Transferrin Binding Protein A in complex with transferrin (iron bound in N lobe only)

Transferrin Binding Protein A in complex with transferrin binding protein B and transferrin (iron bound to N lobe only)

beta-barrel assembly machine from Escherichia coli in an late state of LptD assembly

Capping protein bound to the barbed end of F-actin, actin local refinement

Capping protein bound to the barbed end of cofilactin, consensus refinement

Capping protein bound to the barbed end of cofilactin, co-bound with cofilin on the B-1 actin, consensus map

Capping protein bound to the barbed end of cofilactin, co-bound with cofilin on the B-1 actin, actin local refinement

Capping protein bound to the barbed end of cofilactin, co-bound with cofilin on the B-1 actin, capping protein local refinement

Capping protein bound to the barbed end of cofilactin, actin local refinement

Capping protein bound to the barbed end of cofilactin, barbed end local refinement

Capping protein bound to the barbed end of F-actin, Consensus refinement

Cryo-EM structure of a tmRNA-rescue complex imaged in a cell lysate

The SRA domain of human UHRF1 bound to a mononucleosome with hemimethylated DNA at superhelical location -6.2.

UHRF1 bound to a mononucleosome in its pre-active state, with the RING domain bound to the SRA domain.

Consensus map of human UHRF1 bound to mononucleosome with hemimethylated DNA at superhelical location -6.2.

The focused refinement map of the TTD-PHD domain of UHRF1 bound to a mononucleosome with hemimethylated DNA at superhelical location -6.2.

The RING domain of human UHRF1 bound to a mononucleosome in its pre-active state.

The activated state of human UHRF1 bound to a mononucleosome, with the finger loop ordered and linker 4 disordered.

Human UHRF1 bound to a mononucleosome with hemimethylated DNA at superhelical location -5.6.

Cryo-EM structure of 70S ribosome in the classical state (P/P, E/E) imaged in a cell lysate

Cryo-EM structure of 70S ribosome in the classical state (A/A, P/P, E,E) imaged in a cell lysate

Cryo-EM structure of 70S ribosome bound to RaiA imaged in a cell lysate

Human UHRF1 bound to a mononucleosome with hemimethylation at superhelical location -6.2 and a Histone H3K9me3 methylation mark.