EMD-73525

Single-particle
2.66 Å
EMD-73525
3D View Gallery
Deposition: 23/10/2025
Map released: 26/08/2026
Last modified: 26/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-73525

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9yvi summary report (pdf.gz) Map-9yvi FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of BA.5 spike in complex with S22

EMD-73525

Single-particle
2.66 Å
EMD-73525
3D View Gallery
Deposition: 23/10/2025
Map released: 26/08/2026
Last modified: 26/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Severe acute respiratory syndrome coronavirus 2
Sample: BA.5 spike in complex with S22
Fitted models: 9yvi

Deposition Authors: Mou H, Gao B, Ye G, Bu F, Zhang L, Farzan M, Li F, Choe H

A SARS-CoV-2 entry inhibitor trimerizes to lock the spike trimer in its closed conformation
Mou H, Gao B, Ye G, Bu F, Zhang L, Farzan M, Li F, Choe H
To Be Published