EMD-49668

Single-particle
2.16 Å
EMD-49668
3D View Gallery
Deposition: 12/03/2025
Map released: 26/08/2026
Last modified: 26/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49668

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9nql summary report (pdf.gz) Map-9nql FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo electron microscopic analysis of the adduct of syringolin analog with the Mtb 20S proteasome

EMD-49668

Single-particle
2.16 Å
EMD-49668
3D View Gallery
Deposition: 12/03/2025
Map released: 26/08/2026
Last modified: 26/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mycobacterium tuberculosis
Sample: Mycobacterium tuberculosis proteasome with modified syringolin inhibitor
Fitted models: 9nql

Deposition Authors: Gu X, Yu Z
Substrate Mimicry by Inhibitors of the Mycobacterium tuberculosis 20S Proteasome and Their Activity against Mycobacteria In Vitro and in Macrophages
Gu X, Rowheder PJ, Yu Z, Mohapatra A, Lun S, Jiang X, Li D, Yan NL, Detomasi TC, Pomares DFT, Chen Y, Gestwicki JE, Lin G, Bishai WR, Ernst JD, Cheng Y, Craik CS, Sello JK
(2026) ACS Chem Biol
DOI: doi:10.1021/acschembio.6c00448
ISSN: 1554-8937
Grant Support: