EMD-56081
GABA-A receptor a3b3g2 + a3NB77 + bicuculline
EMD-56081
Single-particle2.87 Å
Deposition: 15/12/2025Map released: 26/08/2026
Last modified: 26/08/2026
Sample Organism:
Homo sapiens,
Lama glama
Sample: alpha3-beta3-gamma2 GABA-A receptor in complex with bicuculline and nanobody a3NB77
Fitted models: 9tnb
Deposition Authors: Shang C
,
Nestorow SA,
Miller PS
Sample: alpha3-beta3-gamma2 GABA-A receptor in complex with bicuculline and nanobody a3NB77
Fitted models: 9tnb
Deposition Authors: Shang C
,
Nestorow SA,
Miller PS
Determining the molecular and physiological actions of subtype-selective nanobodies of GABA A receptors.
Gonzalez-Prada JE ,
Liu S ,
Shang C ,
Chernoff CS ,
Bright DP ,
Mortensen M ,
Jones CF,
Nestorow S ,
Kasaragod VB ,
Chen WN,
Hannan S ,
Zhou J ,
Dunn AWE ,
Soltani A,
Turner RJ ,
Duggan NM,
Yuan Y ,
Wahid AA ,
Hardwick SW ,
Scott S ,
Chirgadze DY ,
Pardon E ,
Steyaert J ,
Aricescu AR ,
Paulsen O ,
Belin D ,
Smart TG ,
Miller PS
(2026) Sci Adv , 12 , eaeg3548 - eaeg3548
,
Liu S ,
Shang C ,
Chernoff CS ,
Bright DP ,
Mortensen M ,
Jones CF,
Nestorow S ,
Kasaragod VB ,
Chen WN,
Hannan S ,
Zhou J ,
Dunn AWE ,
Soltani A,
Turner RJ ,
Duggan NM,
Yuan Y ,
Wahid AA ,
Hardwick SW ,
Scott S ,
Chirgadze DY ,
Pardon E ,
Steyaert J ,
Aricescu AR ,
Paulsen O ,
Belin D ,
Smart TG ,
Miller PS
(2026) Sci Adv , 12 , eaeg3548 - eaeg3548
Grant Support:
- Biotechnology and Biological Sciences Research Council (BBSRC): BB/M024709/1 (United Kingdom)