Asymmetric architecture and adaptation of Treponema flagella

Asymmetric architecture and adaptation of Treponema flagella

The CryoEM structure of T10 type1 nanofiber

The CryoEM structure of T8 nanofiber

Rabbit Aldolase, Laser Phase Plate TEM, Laser-ON dataset 2 (A2)

Rabbit Aldolase, Laser Phase Plate TEM, Laser-ON dataset 3 (A3)

Rabbit Aldolase, Laser Phase Plate TEM, Laser-OFF dataset 3 (A3)

Human Hemoglobin, Laser Phase Plate TEM, Laser-ON dataset 2 (H2)

Subtomogram averaging of vancomycin-resistant Enterococcus faecium (delSagA)

Human Hemoglobin, Laser Phase Plate TEM, Laser-OFF dataset 2 (H2)

Subtomogram averaging of vancomycin-resistant Enterococcus faecium (delSagA-complemented)

Subtomogram averaging of vancomycin-resistant Enterococcus faecium (vancomycin + pghi-4 treated)

Plasmodium falciparum moving junction staple - PfAMA1, PfRON2, PfRON4, PfRON5

Plasmodium falciparum moving junction staple - Particle subtracted, local refined C-terminus of PfRON5 (alternative)

Structure of E. coli WbaP in complex with a megabody

Plasmodium falciparum moving junction staple - Consensus map of PfRON2,PfRON4,PfRON5

Plasmodium falciparum moving junction staple - Particle subtracted, local refined PfAMA1

Plasmodium falciparum moving junction staple - Particle subtracted, local refined C-terminus of PfRON5

ATAD3A structurally links mtDNA replication and mitochondrial fission

The structure of DbOR67d-DbOrco in the Z11-bound state

The structure of DbOR67d-DbOrco in the cVA-bound state

The structure of DmOR67d-DmOrco in the apo state

The structure of DbOR67d-DbOrco in the apo-like state

Cryo-EM structure of the Retron-Eco8 complex

The structure of DbOR67d-DbOrco in the VUAA1-bound state

Cryo-EM structure of the cebranopadol-NOP receptor-Gi complex

Cryo-EM structure of the Retron-Eco8 complex in the presence of ATP

Cryo-EM structure of CeTECR-CeHACD complex

Cryo-EM structure of the cebranopadol-mu opioid receptor-Gi complex

Structure of E. coli WbaP in complex with a megabody in the presence of UDP-Gal processed in C2 symmetry

Structure of C5a anaphylatoxin chemotactic receptor 2, C5aR2 bound to R8Y

Structure of mC5aR2 in complex with mC5a-desArg

Structure of C5a anaphylatoxin chemotactic receptor 2, C5aR2 in the Apo state

Cryo-EM structure of GPR84-Gi complex with DL-175 (Gi focus)

Cryo-EM structure of GPR84 with GLPG1205

Cryo-EM structure of GPR84-Gi with DL-175 (foucus receptor)

Structure of C5a anaphylatoxin chemotactic receptor 2, C5aR2 bound to EP54

Structure of C5a anaphylatoxin chemotactic receptor 2, C5aR2 bound to C5a

Cryo-EM structure of GPR84-Gi complex with DL-175 (Consensus)

Structure of C5a anaphylatoxin chemotactic receptor 2, C5aR2 bound to C5a-pep

Cryo-EM structure of GPR84-Gi complex with DL-175

Structure of mC5aR2 in complex with mC5a-desArg (Monomer)

LamB binding with bacteriophage Lom

UapA (WT) in DDM, Apo state

Assembly intermediate of human mitochondrial ribosome small subunit bound to METTL15, RBFA, and mtIF2 (State M2.1)

Assembly intermediate of human mitochondrial ribosome small subunit bound to METTL15 and RBFA (Inward conformation) (State M2)

Cryo-EM structure of AtCas9-sgRNA-underwound DNA (TTGA) ternary complex

Cryo-EM structure of AtCas9-sgRNA-B-form DNA ternary complex

A cryo-EM structure of GLP1-Y11-GLP1R-Gs complex

Cryo-EM structure of AtCas9-sgRNA-underwound DNA (CATA PAM) ternary complex

Cryo-EM structure of AtCas9-sgRNA-underwound DNA (TATA PAM) ternary complex

Closed-state structure of wild-type human TRPV3 purified in GDN detergent

Inactivated-state structure of wild-type human TRPV3 purified in GDN detergent

Phage tail tube protein from EMPIAR-11785

Antibody BV57-A.01 bound to HIV Env CH848.3.D0949.10.17chim.6R.DS.SOSIP.664_N133D_N138T

Antibody 44715-B.01 bound to HIV Env 25710 SOSIP trimer

Yeast co-transcriptional pre-60S assembly intermediate Pwp1 RNP - Pwp1 focused map

Yeast co-transcriptional pre-60S assembly intermediate Pwp1 RNP* - Overall map

Yeast co-transcriptional pre-60S assembly intermediate Pwp1 RNP - Overall map

Antibody 44645-A.01 bound to HIV Env 25710 SOSIP trimer

Yeast co-transcriptional pre-60S assembly intermediate Pwp1 RNP* - Rpl8 focused map

Yeast co-transcriptional pre-60S assembly intermediate Pwp1 RNP* - Pwp1 focused map

Yeast co-transcriptional pre-60S assembly intermediate Nop12 RNP - Overall map

Yeast co-transcriptional pre-60S assembly intermediate pre-Nop12 RNP - Cic1 focused map

Yeast co-transcriptional pre-60S assembly intermediate Nop12 RNP - Has1 focused map

Yeast co-transcriptional pre-60S assembly intermediate pre-Nop12 RNP - Brx1 focused map

Yeast co-transcriptional pre-60S assembly intermediate pre-Nop12 RNP - Overall map

Yeast co-transcriptional pre-60S assembly intermediate pre-Nop12 RNP - Nop7 focused map

Yeast co-transcriptional pre-60S assembly intermediate pre-Nop12 RNP - Has1 focused map

Yeast co-transcriptional pre-60S assembly intermediate Nop12 RNP - Brx1 focused map

Yeast co-transcriptional pre-60S assembly intermediate Nop12 RNP - Cic1 focused map

Yeast co-transcriptional pre-60S assembly intermediate Nop12 RNP - Nop12 focused map

Yeast co-transcriptional pre-60S assembly intermediate Nop12 RNP - Composite map

Yeast co-transcriptional pre-60S assembly intermediate pre-Nop12 RNP - Composite map

Yeast co-transcriptional pre-60S assembly intermediate Nop12 RNP - Nop7 focused map

Yeast co-transcriptional pre-60S assembly intermediate Pwp1 RNP* - Composite map

Yeast co-transcriptional pre-60S assembly intermediate Pwp1 RNP - Composite map

The density map of BoNT/A mutant (BoNT/A-WFY)

KL-H15-6F6 Fab in complex with soluble A/wedge-tailed shearwater/Western Australia/2576/1979 H15 hemagglutinin trimer

Negative stain map of H15 HA (A/wedge-tailed shearwater/Western Australia/2576/1979) in complex with monoclonal Fab 3G11

07-5G01 Fab in complex with soluble A/wedge-tailed shearwater/Western Australia/2576/1979 H15 hemagglutinin trimer

Negative stain map of H15 HA (A/wedge-tailed shearwater/Western Australia/2576/1979) in complex with monoclonal Fab 6F6

KL-H15-6H4 Fab in complex with soluble A/wedge-tailed shearwater/Western Australia/2576/1979 H15 hemagglutinin trimer

KL-H15-6G8 Fab in complex with soluble A/wedge-tailed shearwater/Western Australia/2576/1979 H15 hemagglutinin trimer

Negative stain map of H15 HA (A/wedge-tailed shearwater/Western Australia/2576/1979) in complex with monoclonal Fab 6G8

Lipid droplet biogenesis by the seipin complex

KL-H15-3G11 Fab in complex with soluble A/wedge-tailed shearwater/Western Australia/2576/1979 H15 hemagglutinin trimer

Heterodisulfide reductase-Formylmethanofuran dehydrogenase super-assembly

Structure of the complex of human PD-1 and a PD-1-directed antibody

Composite map of the Hdr-Vhu-Fdh dimer

Local Refinement of the HdrABC-dimer from the eight-megadalton Hdr-Vhu-Fwd super-assembly

Local refinement map of the Vhu hydrogenase of the Hdr-Vhu-Fdh complex

Cryo-EM structure of the R162W mutant inward rectifying potassium channel 7.1 (Kir7.1)

Assembly intermediate of human mitochondrial ribosome small subunit bound to METTL15 and RBFA (Outward conformation) (State M3)

Local refinement of the inner region of FwdABCDG from the eight mega-dalton Hdr-Vhu-Fwd super-assembly

Local refinement of the outer FwdABCDG-complex from the eight-megadalton Hdr-Vhu-Fwd super-assembly

Cryo-EM structure of the inward rectifying potassium channel 7.1 (Kir7.1) in complex with PIP2

Local refinement map of the formate dehydrogenase of the Hdr-Vhu-Fdh complex

Local refinement of VhuB from the eight-megadalton Hdr-Vhu-Fwd super-assembly

Consensus map of the eight- megadalton Hdr-Vhu-Fwd super-assembly

Cryo-EM structure of the inward rectifying potassium channel 7.1 (Kir7.1)

Local refinement of VhuB from the eight-megadalton Hdr-Vhu-Fwd super-assembly, state 2

human mitochondrial ribosome small subunit: Initiation complex with IF3 (State I2)

Assembly intermediate of human mitochondrial ribosome small subunit bound to METTL15 and mS37 (State M4)

Local refinement of FwdF from the eight-megadalton Hdr-Vhu-Fwd super-assembly

P2a-state of wild type human mitochondrial LONP1 protease with bound substrate protein, ADP and aluminum fluoride

Human mitochondrial small ribosomal subunit: Assembly intermediate with IF3 and RBFA-out (state I1)

Human mitochondrial small ribosomal subunit: Initiation complex with IF2 and tRNA (state I4)

Human mitochondrial small ribosomal subunit: Initiation complex with IF2 and IF3 (State I3)

Cryo-EM structure of CDK2 in complex with CRBN/DDB1 and B11

Cryo-EM structure of CDK2 in complex with CRBN/DDB1 and B11 local refinement (Masked on CDK2-CRBN-DDB1)

Cryo-EM structure of CDK2 in complex with CRBN/DDB1 and B11 local refinement (Masked on CDK2-CRBN)

Cryo-EM structure of CDK2 in complex with CRBN/DDB1 and B11 consensus refinement

The structure of BoNT/A in complex with a neutralizing antibody 2G11

UapA (Q408E) in MSP1E3D1 nanodiscs, Xanthine-bound state

UapA (Q408E) in DDM, Apo state

HCMV trimer in complex with G1L (II), G1L (A), B5L, C4K, B1K, A7K, A12K, and C5K Fabs

HCMV trimer in complex with E4K, E11K, A9K, E9L, E8K, B1K, E7K, F12L and E10L Fabs

Quasibacillus thermotolerans T=4 encapsulin pore mutant variant Glass 9

Human cytomegalovirus UL52 4-mer

HSV-1 UL32 tripentamer

Structure of human TRPV3-G568C Olmsted syndrome mutant in the open state

Quasibacillus thermotolerans T=3 encapsulin pore mutant variant Letter11

Structure of human TRPV3-G568D Olmsted syndrome mutant in the 4-fold symmetrical inactivated state

Structure of human TRPV3-G568D Olmsted syndrome mutant in the 2-fold symmetrical open state

Structure of human TRPV3-W692G Olmsted syndrome mutant in the open state

Structure of human TRPV3-G568C Olmsted syndrome mutant in the closed state

Structure of human TRPV3-Q580P Olmsted syndrome mutant in the open state

Human cytomegalovirus UL52 3-mer

Quasibacillus thermotolerans T=4 encapsulin pore mutant variant Letter11

Structure of human TRPV3-W692G Olmsted syndrome mutant in the inactivated state

Structure of human TRPV3-Q580P Olmsted syndrome mutant in the inactivated state

Structure of human TRPV3-G568D Olmsted syndrome mutant in the 4-fold symmetrical open state

Structure of human TRPV3-W521S Olmsted syndrome mutant in the closed state

Structure of human TRPV3-G568D Olmsted syndrome mutant in the 2-fold symmetrical closed state

Autoinhibited P-Rex2 Local Refinement of N-terminal Module

Autoinhibited P-Rex2 Local Refinement of Whole Particle

Autoinhibited P-Rex2 Consensus Map

Human 19S proteasome bound to TXNL1 PITH domain but with low density for RPT1, RPT2, and RPN1

Structure of the Adenovirus-7 VLP, Class 2

Structure of the Adenovirus-7 VLP, Class 3

Structure of the Adenovirus-7 VLP, Class 4

Human 19S proteasome bound to TXNL1 PITH domain and PSMD5

Structure of the Adenovirus-7 VLP, Class 1

Thermosynechococcus vestitus (BP-1) Photosystem I Complexed with Platinum Nanoparticles

Half-translocated RNA polymerase elemental paused elongation complex, swiveled with ppGpp (ePEC swiveled + ppGpp)

Human 19S proteasome bound to TXNL1 PITH domain state 2

FcgRIIa in complex with IV.3 Fab

Half-translocated RNA polymerase elemental paused elongation complex, swiveled (ePEC swiveled)

Pre-translocated RNA polymerase elemental paused elongation complex, TL open with ppGpp (ePEC open + ppGpp)

PRC2(EZH2 WT) AJ106-350 in the compact active state

Pre-translocated RNA polymerase elemental paused elongation complex, TL open (ePEC open)

PRC2(EZH2 S21A) AJ106-350 in the extended active state

Pre-translocated RNA polymerase elemental paused elongation complex, TL semiclosed (ePEC semiclosed)

PRC2(EZH2 WT) AJ106-350 in the extended active state

Pre-translocated RNA polymerase elemental paused elongation complex, TL closed (ePEC closed)

PRC2(EZH2 S21A) AJ106-350 in the compact active state

Pre-translocated RNA polymerase elemental paused elongation complex, TL closed with ppGpp (ePEC closed + ppGpp)

Pre-translocated RNA polymerase elemental paused elongation complex, TL semiclosed with ppGpp (ePEC semiclosed + ppGpp)

Cryo-EM structure of human papillomavirus type 45 in complexed with the Fab fragment of A14D2

Cryo-EM structure of human papillomavirus type 45 in complexed with the Fab fragment of A20C10

HIV-1 capsid hexamers in presence of LEN

HIV-1 capsid hexamers after 3 days post infection without Lenacapavir

HIV-1 capsid hexamers in presence of LEN with C6 symmetry

The ERAD misfolded glycoprotein checkpoint complex from Chaetomium thermophilum (EDEM:PDI heterodimer).

80S ribosomes from primary B-cells infected with delta v-snoRNA1 EBV

Human 19S proteasome regulatory particle bound to TXNL1 PITH domain and p28

Ligand-free kappa-opioid receptor in complex with Gi1

Human 26S proteasome bound to TXNL1 with opened gate of core particle

(S)-ketamine bound mu-opioid receptor in complex with Gi1

Human 19S proteasome regulatory particle (RP) without observing TXNL1 PITH domain bound but with extra density adjacent to RPT1/RPT2

Human 26S proteasome bound to TXNL1 with closed gate of core particle

(S)-ketamine bound kappa-opioid receptor in complex with Gi1

Human 19S proteasome regulatory particle (RP) without observing TXNL1 PITH domain bound

3-OH-PCP bound mu-opioid receptor in complex with Gi1

PCP bound kappa-opioid receptor in complex with Gi1

PCP bound mu-opioid receptor in complex with Gi1

NHEJ Short-range complex with Polymerase lambda

Human 19S proteasome bound to TXNL1 PITH domain without C-terminus

De novo assembled CBF3-CEN complex

Proximal Ku-LigIV catalytic domain-Pol lambda BRCT

NHEJ Short-range Pol lambda complex (consensus map)

Structure of the Measles virus Hemagglutinin ectodomain in complex with two neutralizing antibodies 1C08 and 4D08

XRCC4-XLF Scafoold

Structure of the Measles virus Fusion glycoprotein ectodomain in complex with two neutralizing antibodies 4F09 and 3A12

Distal Ku-Polymerase lambda BRCT

Structure of the Measles virus Hemagglutinin ectodomain in complex with neutralizing antibody 1C08

Structure of the Measles virus Hemagglutinin ectodomain in complex with neutralizing antibody 1C02

CryoEM structure of class Ib RNR from Mycobacterium thermoresistibile, conformer G

CryoEM structure of classIbRibonucleotide reductase from Mycobacterium thermoresistibile, conformer B

CryoEM structure of class Ib RNR from Mycobacterium thermoresistibile, conformer E

CryoEM structure of class Ib RNR from Mycobacterium thermoresistibile, conformer C

CryoEM structure of class Ib RNR from Mycobacterium thermoresistibile, conformer F

CryoEM structure of class Ib Ribonucleotide reductase from Mycobacterium thermoresistibile, conformer D

CryoEM structure of class Ib RNR from Mycobacterium thermoresistibile, conformer A

Cryo-ET structure of actin branch junction from B16F10 cells.

Cryo-ET structure of Arp2/3 inhibition branch protrusion from B16F10 cells.

Structure of substrate-bound ABCD4-LMBD1 complex

Structure of cytosol-open ABCD4-LMBD1

Structure of lumen-open ABCD4-LMBD1 complex

Local density map of Sudan ebolavirus GP2 bound by neutralizing antibodies 294S

Cryo-EM structure of TRP melastatin channel in the desensitized state, with icilin

RNA polymerase II elongation complex stalled at SHL(-6) in the hexasome of the overlapping dinucleosome

Cryo-EM structure of TRP melastatin channel in the desensitized state, without CHS

Cryo-EM structure of Enterovirus-D68 MO strain virus-like particle

Cryo-EM structure of TRP melastatin channel in the intermediate 3 state

Structure of dodecameric Apo TpkB from Thermus thermophilus

cryo-EM structure of PSII D1-V185T from Thermosynechococcus vestitus BP-1

Structure of hexameric TpkB bound to AMP-PNP from Thermus thermophilus

RNA polymerase II elongation complex stalled at SHL(-0.5) in the hexasome of the overlapping dinucleosome

Structure of dodecameric TpkB bound to AMP-PNP from Thermus thermophilus

Cryo-EM structure of TRP melastatin channel in the desensitized state, with CHS

CryoEM structure of GasderminE-N pore

The cryo-electron microscopy complex structure of PCV3 VLPs and antibody 2B5

Cryo-EM structure of PCV3 VLPs

CryoEM structure of NADH:quinone oxidoreductases YjlCD fiber's N-terminal extremity from Bacillus subtilis

IF1 bound bovine ATP synthase tetramer, no symmetry imposed

IF1 bound bovine ATP synthase tetramer: Fo focused map of the state 1 protomer of dimer B

IF1 bound bovine F-ATP synthase planar dimer

CryoEM structure of a catalytically inactive CXC Chemokine-degrading protease SpyCEP from Streptococcus pyogenes complexed with an anti-PA-domain monoclonal antibody

Structure of human excitatory amino acid transporter 3 (EAAT3) in complex with B11 nanobody

IF1 bound bovine ATP synthase monomer, rotary state 2, F1 focused map

IF1 bound bovine ATP synthase monomer: rotary state 1, F1 focused map

IF1 bound bovine ATP synthase monomer, rotary state 2

IF1 bound bovine ATP synthase monomer: rotary state 3

IF1 bound bovine ATP synthase monomer: rotary state 2, Fo focused map

CryoEM structure of a catalytically inactive CXC Chemokine-degrading protease SpyCEP from Streptococcus pyogenes complexed with an anti-N-terminal monoclonal antibody

CryoEM structure of NADH:quinone oxidoreductases YjlCD fiber's HMP extremity from Bacillus subtilis

IF1 bound bovine ATP synthase monomer: rotary state 3, F1 focused map

IF1 bound bovine ATP synthase tetramer, C2 symmetry imposed

IF1 bound bovine ATP synthase monomer: rotary state 3, Fo focused map

Structures of large semifused vesicles connecting to presynaptic membrane

Structures of large pore-opened vesicles connecting to presynaptic membrane

IF1 bound bovine ATP synthase monomer: rotary state 1, Fo focused map

Cryo-EM structure of retron Ec78 effector protein PtuA hexamer

IF1 bound bovine ATP synthase monomer: rotary state 1

Structures of small semifused vesicles connecting to presynaptic membrane

Cryo-EM structure of the Mycobacterium abscessus cytochrome bcc:aa3 supercomplex

Structure of glycerol-3-phosphate acyltransferase PlsB from Escherichia coli

Cryo-EM structure of the Mycobacterium abscessus cytochrome bcc:aa3 supercomplex in the presence of ND-011458

Structures of small pore-opened vesicles connecting to presynaptic membrane

Structure of glycerol-3-phosphate acyltransferase PlsB from Themomonas haemolytica in complex with Palmitoyl-CoA and DOPA

CryoEM struccture of the type III secretion system gatekeeper protein InvE by cryo-electron microscopy.

Cryo-EM structure of chimeric immunoglobulin M comprising bony fish and human sequences, hFcm-tFcm-chi3

Cryo-EM structure of chimeric immunoglobulin M comprising bony fish and human sequences, hFcm-tFcm-chi4

HCoV-HKU1 C S 2P in complex with H501-008 Fab (global cryoEM)

Structure of the Adenovirus-7 VLP

Structure of the Adenovirus-7 PB-Fiber

HuCoV-HKU1 C S 2P in complex with H501-018 Fab (State 1, global cryoEM)

HCoV-HKU1 C S 2P in complex with H501-022 Fab (local cryoEM)

HCoV-HKU1 C S 2P in complex with H501-018 Fab (local cryoEM)

HCoV-HKU1 C S 2P in complex with H501-022 Fab (global cryoEM)

HuCoV-HKU1 C S 2P in complex with H501-018 Fab (State 2, global cryoEM)

CryoEM map of Yeast RNA polymerase II elongation complex with ATP-3D class G (frame 13)

Human UAP56-RNA - SAC3D1-PCID2-SEM1 complex, Map A

Structure of Yeast RNA polymerase II elongation complex with NTP-state-VII-B

CryoEM map of Yeast RNA polymerase II elongation complex with ATP-3D class F (frame 10)

CryoEM map of Yeast RNA polymerase II elongation complex with ATP-3D class B (frame4)

Map B of the human UAP56-RNA - SAC3D1-PCID2-SEM1 complex

CryoEM map of Yeast RNA polymerase II elongation complex with ATP-3D class C (frame7)

CryoEM map of Yeast RNA polymerase II elongation complex with ATP-3D class E (frame9)

Structure of Yeast RNA polymerase II elongation complex with ATP frame-1

CryoEM map of Yeast RNA polymerase II elongation complex with ATP-3D class D (frame8)

CryoEM map of Yeast RNA polymerase II elongation complex with ATP-3D class H (frame 15)

Structure of Yeast RNA polymerase II elongation complex with NTP-state-II

Structure of Yeast RNA polymerase II elongation complex with NTP-state-VII-D

CryoEM map of Yeast RNA polymerase II elongation complex with ATP-3D class J (frame 20)

CryoEM map of Yeast RNA polymerase II elongation complex with ATP-3D class A (frame1)

CryoEM map of Yeast RNA polymerase II elongation complex with ATP-3D class I (frame 17)

Structure of Yeast RNA polymerase II elongation complex with ATP frame-2

Structure of Yeast RNA polymerase II elongation complex with NTP-state-VI

Structure of Yeast RNA polymerase II elongation complex with ATP frame-4

Structure of Yeast RNA polymerase II elongation complex with ATP frame-3

Structure of Yeast RNA polymerase II elongation complex with ATP frame-5

Structure of Yeast RNA polymerase II elongation complex with ATP frame-6

Structure of Yeast RNA polymerase II elongation complex with ATP frame-8

Structure of Yeast RNA polymerase II elongation complex with ATP frame-19

Structure of Yeast RNA polymerase II elongation complex with ATP frame-12

Structure of Yeast RNA polymerase II elongation complex with ATP frame-9

Structure of Yeast RNA polymerase II elongation complex with ATP frame-20

Structure of Yeast RNA polymerase II elongation complex with ATP frame-15

Structure of Yeast RNA polymerase II elongation complex with ATP frame-11

Structure of Yeast RNA polymerase II elongation complex with ATP frame-14

Structure of Yeast RNA polymerase II elongation complex with ATP frame-10

Structure of Yeast RNA polymerase II elongation complex with ATP frame-18

Structure of Yeast RNA polymerase II elongation complex with ATP frame-13

Structure of Yeast RNA polymerase II elongation complex with ATP frame-7

Structure of Yeast RNA polymerase II elongation complex with ATP frame-17

Structure of Yeast RNA polymerase II elongation complex with NTP-state-III

Cryo-EM structure of the yeast RNA polymerase II elongation complex with 19-mer RNA in State III (TL-open), in the presence of substrate ATP

Cryo-EM structure of the yeast RNA polymerase II elongation complex with 19-mer RNA in State V (TL-closed), in the presence of substrate ATP

Structure of Yeast RNA polymerase II elongation complex with ATP frame-16

CryoEM structure of NADH:quinone oxidoreductases YjlCD from Bacillus subtilis

Cryo-EM structure of the DCAF11 E3 ligase bound to the DDX18 helicase mediated by GSH-M12 (consensus refinement)

Cryo-EM structure of the DCAF11 E3 ligase bound to the DDX18 helicase mediated by GSH-M12 (DDX18 local refinement)

Cryo-EM structure of the DCAF11 E3 ligase bound to the DDX18 helicase mediated by GSH-M12

Cryo-EM structure of Nitrogenase MoFe protein from Methanosarcina acetivorans bound to the NifI inhibitor complex

Cryo-EM structure of the human TRPM4 channel bound to NC1 in the presence of EGTA.

Cryo-EM structure of the human TRPM4 channel in an open state bound to NC1 and PI(4,5)P2 in the presence of EGTA.

Cryo-EM structure of the mouse TRPM4 channel bound to NC1 and PI(4,5)P2.

Cryo-EM structure of the L900V;R993P;S1060R mutant mouse TRPM4 channel in an open state bound to NC1 and PI(4,5)P2.

Cryo-EM structure of the human TRPM4 channel in an open state bound to NC1 and PI(4,5)P2.

Cryo-EM structure of the mouse TRPM4 channel bound to NC1.

Cryo-EM map of norovirus GII.4 SY 2012 VLP in complex with VX77 Fab

Cryo-EM map of norovirus GII.4 SY 2012 VLP in complex with VX93 Fab - threefold axis local map (2 Fabs-1)

Cryo-EM map of norovirus GII.4 SY 2012 VLP in complex with VX93 Fab - fivefold axis local map (4 Fabs)

Cryo-EM map of norovirus GII.4 SY 2012 VLP in complex with VX93 Fab - threefold axis local map (2 Fabs-2)

Structure of E. coli WbaP in complex with a megabody

Structure of a stalled E. coli 70S RNC-NuoK-70 in complex with the membrane protein insertase SecYEG-YidC

Structure of E. coli WbaP in complex with a megabody in presence of UDP-Gal

Cryo-EM structure of VX93 Fab in complex with GII.4 Norovirus P domain

IP3/ATP-bound human type 2 IP3 receptor in the preactivated state

Human type 2 IP3 receptor apo state ARM3-JD domain local refinement

Human type 2 IP3 receptor in apo state

Local refined ARM2 domain of IP3/ATP bound human type 2 IP3 receptor in the resting state

Human type 2 IP3 receptor apo state transmembrane domain (TMD) local refinement

IP3/ATP bound human type 2 IP3 receptor in the resting state - Consensus map

Local refined central linker domain (CLD) of IP3/ATP bound human type 2 IP3 receptor in the resting state

Local refined central linker domain (CLD) of IP3/ATP-bound human type 2 IP3 receptor in the preactivated state

Local refined ligand-binding domain (LBD) of IP3/ATP bound human type 2 IP3 receptor in the resting state

Human type 2 IP3 receptor apo state consensus map

IP3/ATP-bound human type 2 IP3 receptor in the preactivated state - Consensus map

Cryo-EM map of norovirus GII.4 SY 2012 VLP in complex with VX93 Fab - threefold axis local map (2 Fabs-3)

Local refined ARM2 domain of IP3/ATP-bound human type 2 IP3 receptor in the preactivated state

Local refined ligand-binding domain (LBD, chain A) of human type 2 IP3 receptor in the inactive-like state (IP3/ATP)

Local refined ARM3-JD (chain C) of human type 2 IP3 receptor in the inactive-like state (IP3/ATP)

Human type 2 IP3 receptor in the inactive-like state (IP3/ATP/Ca2+) Consensus Map

Local refined ARM2 (chain B) of human type 2 IP3 receptor in the inactive-like state (IP3/ATP)

Local refined JD (chain D) of human type 2 IP3 receptor in the inactive-like state (IP3/ATP

Local refined transmembrane domain (TMD) of human type 2 IP3 receptor in the inactive-like state (IP3/ATP)

Local refined ARM2 (chain A) of human type 2 IP3 receptor in the inactive-like state (IP3/ATP/Ca2+)

Local refined ligand-binding domain (LBD, chain A) of human type 2 IP3 receptor in the inactive-like state (IP3/ATP/Ca2+)

Local refined ARM3-JD (chain A) of human type 2 IP3 receptor in the inactive-like state (IP3/ATP/Ca2+)

Local refined ARM2 (chain B) of human type 2 IP3 receptor in the inactive-like state (IP3/ATP/Ca2+)

Local refined ARM3-JD (chain B) of human type 2 IP3 receptor in the inactive-like state (IP3/ATP/Ca2+)

Local refined ARM3-JD (chain C) of human type 2 IP3 receptor in the inactive-like state (IP3/ATP/Ca2+)

Human type 2 IP3 receptor dimer (IP3/ATP/Ca2+)

Human type 2 IP3 receptor in the inactive-like state (IP3/ATP/Ca2+)

Local refined central linker domain (CLD, chain A) of human type 2 IP3 receptor in dimer (IP3/ATP/Ca2+)

Local refined dimerization interface of human type 2 IP3 receptor dimer (IP3/ATP/Ca2+)

Human type 2 IP3 receptor dimer complete map (IP3/ATP/Ca2+)

Local refined N-terminal domain (NTD, chain B) of human type 2 IP3 receptor dimer (IP3/ATP/Ca2+)

Human type 2 IP3 receptor in the inactive-like state (ligand-free)

Local refined ARM3-JD (chain A) of human type 2 IP3 receptor dimer (IP3/ATP/Ca2+)

Human type 2 IP3 receptor in the intermediate state 3 (IP3/ATP)

Rabbit Aldolase, Laser Phase Plate TEM, Laser-ON dataset 1 (A1)

Asymmetric architecture and adaptation of Treponema flagella

Rabbit Aldolase, Laser Phase Plate TEM, Laser-OFF dataset 1 (A1)

Rabbit Aldolase, Laser Phase Plate TEM, Laser-OFF dataset 2 (A2)

Human Hemoglobin, Laser Phase Plate TEM, Laser-ON dataset 1 (H1)

Human Hemoglobin, Laser Phase Plate TEM, Laser-OFF dataset 1 (H1)

Human Hemoglobin, Laser Phase Plate TEM, Laser-OFF dataset 3 (H3)

Human Hemoglobin, Laser Phase Plate TEM, Laser-ON dataset 3 (H3)

Subtomogram averaging of vancomycin-resistant Enterococcus faecium (wt)

Cryo-EM map of norovirus GII.4 SY 2012 VLP in complex with VX93 Fab

Subtomogram averaging of vancomycin-resistant Enterococcus faecium (vancomycin treated)

Subtomogram averaging of vancomycin-resistant Enterococcus faecium (pghi-4 treated)

Cryo-EM structure of VX77 Fab in complex with GII.4 Norovirus P domain

Human Hemoglobin, Laser Phase Plate TEM, Laser-OFF, Refined initial 3D class (IC-OFF)

Human Hemoglobin, Laser Phase Plate TEM, Laser-ON, Refined initial 3D class (IC-ON)

Cryo-EM map of norovirus GII.4 SY 2012 VLP in complex with VX93 Fab - threefold axis local map (1 Fab)

Cryo-EM map of norovirus GII.4 SY 2012 VLP in complex with VX93 Fab - fivefold axis local map (5 Fabs-1)

Cryo-EM map of norovirus GII.4 SY 2012 VLP in complex with VX93 Fab - fivefold axis local map (3 Fabs-1)

Cryo-EM map of norovirus GII.4 SY 2012 VLP in complex with VX93 Fab - fivefold axis local map (5 Fabs-2)

Cryo-EM map of norovirus GII.4 SY 2012 VLP in complex with VX93 Fab - fivefold axis local map (3 Fabs-2)

Local refined ARM3-JD domains of IP3/ATP bound human type 2 IP3 receptor in the resting state

Human type 2 IP3 receptor apo state ARM2 domain local refinement

Cryo-EM map of norovirus GII.4 SY 2012 VLP in complex with VX93 Fab - threefold axis local map (3 Fabs)

Human type 2 IP3 receptor apo state ligand binding domain (LBD) local refinement

Human type 2 IP3 receptor apo state central linker domain (CLD) local refinement

Local refined transmembrane domain (TMD) of IP3/ATP bound human type 2 IP3 receptor in the resting state

IP3/ATP-bound human type 2 IP3 receptor in the resting state

Human type 2 IP3 receptor in the inactive-like state (IP3/ATP) Consensus Map

Local refined ligand-binding domain (LBD) of IP3/ATP-bound human type 2 IP3 receptor in the preactivated state

Local refined ARM2 (chain A) of human type 2 IP3 receptor in the inactive-like state (IP3/ATP)

Local refined central linker domain (CLD, chain A) of human type 2 IP3 receptor in the inactive-like state (IP3/ATP)

Local refined transmembrane domain (TMD) of IP3/ATP-bound human type 2 IP3 receptor in the preactivated state

Local refined ARM3-JD domains of IP3/ATP-bound human type 2 IP3 receptor in the preactivated state

Local refined ARM3-JD (chain A) of human type 2 IP3 receptor in the inactive-like state (IP3/ATP)

Local refined central linker domain (CLD, chain B) of human type 2 IP3 receptor in the inactive-like state (IP3/ATP)

Local refined ARM3-JD (chain B) of human type 2 IP3 receptor in the inactive-like state (IP3/ATP)

Human type 2 IP3 receptor in the inactive-like state (IP3/ATP)

Local refined central linker domain (CLD, chain A) of human type 2 IP3 receptor in the inactive-like state (IP3/ATP/Ca2+)

Local refined JD (chain D) of human type 2 IP3 receptor in the inactive-like state (IP3/ATP/Ca2+)

Local refined central linker domain (CLD, chain B) of human type 2 IP3 receptor in the inactive-like state (IP3/ATP/Ca2+)

Local refined JD and TMD of human type 2 IP3 receptor in the inactive-like state (IP3/ATP/Ca2+)

Human type 2 IP3 receptor dimer (IP3/ATP/Ca2+) Consensus Map

Local refined ARM2 (chain A) of human type 2 IP3 receptor dimer (IP3/ATP/Ca2+)

Local refined JD and TMD of human type 2 IP3 receptor dimer (IP3/ATP/Ca2+)

Human type 2 IP3 receptor in the intermediate state 4 (IP3/ATP)

Cryo-EM structure of a soluble HCV E1E2 antigen in complex with AT1211 fab