EMD-58507
Discodermolide stabilised 14-protofilament microtubule C1 reconstruction
EMD-58507
Single-particle2.73 Å
Deposition: 11/06/2026Map released: 02/09/2026
Last modified: 07/10/2026
Sample Organism:
Sus scrofa
Sample: Microtubule
Deposition Authors: Gravett MSC
,
Howes SC ,
Pelster Jose A
Sample: Microtubule
Deposition Authors: Gravett MSC
,
Howes SC ,
Pelster Jose A
Taxane-induced conformational changes in the microtubule lattice activate GEF-H1-dependent RhoA signalling.
Meiring JCM ,
Mahapatra V,
Liu R,
Gravett MSC ,
Morren D,
Saunders HAJ,
Choi SR,
Pelster Jose A ,
Karhanova A,
Metallidou I,
Moore A,
Spoelstra MFM,
Grigoriev IS,
Giono M,
Iyer SS,
Stehbens SJ ,
Diaz JF ,
Lansky Z ,
Stecker KE,
Steinmetz MO ,
Howes SC ,
Kapitein LC ,
Akhmanova A
(2026) Nat Cell Biol
,
Mahapatra V,
Liu R,
Gravett MSC ,
Morren D,
Saunders HAJ,
Choi SR,
Pelster Jose A ,
Karhanova A,
Metallidou I,
Moore A,
Spoelstra MFM,
Grigoriev IS,
Giono M,
Iyer SS,
Stehbens SJ ,
Diaz JF ,
Lansky Z ,
Stecker KE,
Steinmetz MO ,
Howes SC ,
Kapitein LC ,
Akhmanova A
(2026) Nat Cell Biol
Grant Support:
- H2020 Marie Curie Actions of the European Commission: 101153345 (European Union)
- Netherlands Organisation for Scientific Research (NWO): OCENW.XL21.XL21.048 (Netherlands)