EMD-56520
Cryo-EM map of SKM-70S complex State 2 (Accommodating A-tRNA)
EMD-56520
Single-particle2.3 Å
Deposition: 30/01/2026Map released: 02/09/2026
Last modified: 02/09/2026
Sample Organism:
Escherichia coli B
Sample: Cryo-EM structure of SKM-70S ribosomal stalled complex in the major state (vacant A-site, canon)
Deposition Authors: Morici M
,
Corazza M ,
Safdari HA ,
Wilson DN
Sample: Cryo-EM structure of SKM-70S ribosomal stalled complex in the major state (vacant A-site, canon)
Deposition Authors: Morici M
,
Corazza M ,
Safdari HA ,
Wilson DN
Saskemycin, a potent antimycobacterial agent targeting a unique site in the ribosome
Cook MA ,
Xu M,
Wang W,
Rao VN,
Schaenzer AJ,
Wang L,
Yarlagadda V,
Guitor AK,
Ejim L,
Wright G,
Golas AJ,
Nietupski RM,
Fitzgerald M,
Hung DT,
Sahile H,
Av-Gay Y,
Lin S,
Dhar N,
Travin D,
Klepacki D,
Vazquez-Laslop N,
Mankin A,
Morici M ,
Corazza M ,
Safdari HA ,
Berger M ,
Wilson DN
To Be Published
,
Xu M,
Wang W,
Rao VN,
Schaenzer AJ,
Wang L,
Yarlagadda V,
Guitor AK,
Ejim L,
Wright G,
Golas AJ,
Nietupski RM,
Fitzgerald M,
Hung DT,
Sahile H,
Av-Gay Y,
Lin S,
Dhar N,
Travin D,
Klepacki D,
Vazquez-Laslop N,
Mankin A,
Morici M ,
Corazza M ,
Safdari HA ,
Berger M ,
Wilson DN
To Be Published
Grant Support:
- National Institutes of Health/National Cancer Institute (NIH/NCI): R35 GM127134 (United States)
- National Institutes of Health/National Cancer Institute (NIH/NCI): NIH R01 AI162961 (United States)
- Canadian Institutes of Health Research (CIHR): FDN148463 (Canada)
- German Research Foundation (DFG): WI3285/12-1 (Germany)