EMD-58509
Discodermolide stabilised 13-protofilament microtubule C1 reconstruction
EMD-58509
Single-particle3.47 Å
Deposition: 11/06/2026Map released: 02/09/2026
Last modified: 02/09/2026
Sample Organism:
Sus scrofa
Sample: Microtubule
Deposition Authors: Gravett MSC
,
Howes SC ,
Pelster Jose A
Sample: Microtubule
Deposition Authors: Gravett MSC
,
Howes SC ,
Pelster Jose A
Taxane-Induced Conformational Changes in the Microtubule Lattice Activate GEF-H1-Dependent RhoA Signaling
Meiring JCM,
Mahapatra V,
Liu RR,
Gravett MSC ,
Morren D,
Saunders HAJ,
Choi SR,
Pelster Jose A ,
Karhanova A,
Metallidou I,
Moore A,
Spoelstra MFM,
Grigoriev IS,
Giono M,
Iyer SS,
Stehbens SJ,
Diaz JF,
Lansky Z,
Stecker KE,
Steinmetz MO,
Howes SC ,
Kapitein LC,
Akhmanova A
(2025) bioRxiv
,
Morren D,
Saunders HAJ,
Choi SR,
Pelster Jose A ,
Karhanova A,
Metallidou I,
Moore A,
Spoelstra MFM,
Grigoriev IS,
Giono M,
Iyer SS,
Stehbens SJ,
Diaz JF,
Lansky Z,
Stecker KE,
Steinmetz MO,
Howes SC ,
Kapitein LC,
Akhmanova A
(2025) bioRxiv
Grant Support:
- H2020 Marie Curie Actions of the European Commission: 101153345 (European Union)
- Netherlands Organisation for Scientific Research (NWO): OCENW.XL21.XL21.048 (Netherlands)