EMD-80825

Single-particle
3.23 Å
EMD-80825
3D View Gallery
Deposition: 11/05/2026
Map released: 02/09/2026
Last modified: 30/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-80825

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-26qh summary report (pdf.gz) Map-26qh FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of human UGCG bound to Eliglustat

EMD-80825

Single-particle
3.23 Å
EMD-80825
3D View Gallery
Deposition: 11/05/2026
Map released: 02/09/2026
Last modified: 30/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Ceramide glucosyltransferase UGCG bound to Eliglustat
Fitted models: 26qh

Deposition Authors: Wu C, Jin S, Xu J, Wang JJ, Guo X, Li Y, Cao Z, Jiang M, Yuan Q, Hu W, Li C, Xu Y, Wang MW, Jiang Y, Xu HE
Primate-specific regulation of the human glycosphingolipid gatekeeper UGCG.
Wu C, Jin S, Xu J, Wang JJ, Guo X, Li Y, Cao Z, Jiang M, Yuan Q, Hu W, Li C, Xu Y, Wang MW, Jiang Y, Xu HE
(2026) Nature , 657 , 549 - 558
PUBMED: 42649293
DOI: doi:10.1038/s41586-026-10927-4
ISSN: 1476-4687
ASTM: NATUAS