Pre-activated 9-subunit COP9 signalosome and neddylated SCF (Skp1-Skp2-Cks1) complex structure

Dissociation-state-2 of 9-subunit CSN and SCF (SKP1-SKP2-CKS1) complex

Dissociation-state-1 of 9-subunit CSN and SCF (SKP1-SKP2-CKS1) complex

Type I-F_HNH variant Cascade target-free RNP, HNH domain in outwards position

Type I-F_HNH variant Cascade bound to dsDNA, HNH domain in inwards position

Type I-F_HNH variant Cascade bound to dsDNA, HNH domain in outwards position

Cryo-EM structure of nTr20 tRNA

Type I-F_HNH variant Cascade bound to dsDNA, HNH domain in middle position

Type I-F_HNH variant Cascade bound to dsDNA, HNH domain in inwards position

TAF14 amyloid filament fold B variant 3

TAF15 amyloid filament fold B variant 2

Cryo-EM reconstruction for n-Tr20U.

TAF15 amyloid filament fold B variant 1

Type I-F_HNH variant Cascade bound to dsDNA, HNH domain in outwards position

Cryo-EM structure of ISCro4-DBL-TBL-tDNA-dDNA synaptic complex

TAF15 amyloid filament fold H (Y38C)

TAF15 amyloid filament fold G

TAF15 amyloid filament fold C variant 1 doublet

TAF15 amyloid filament fold C variant 1

TAF15 amyloid filament fold E variant 2

L. pneumophila 3-methylcrotonyl-CoA carboxylase holoenzyme A3B6

NMT1-NAC bound human RNC with full length ARF1 - State 2

TAF15 amyloid filament fold E variant 1

TAF15 amyloid filament fold C variant 2

TAF15 amyloid filament fold F

TAF15 amyloid filament fold D prime

TAF15 amyloid filament fold D

NMT1-NAC bound human RNC with 58 amino acid ARF1-linker - State 1

NMT1-NAC bound human RNC with full length ARF1 - alternative State

NMT1-NAC bound human RNC with full length ARF1 - State 1

NMT1-NAC bound human RNC with 58 amino acid ARF1-linker - State 2

NAC bound human RNC with 58 amino acid ARF1-linker

Cryo-EM structure of E coli pstSCAB in the resting state

Cryo-EM structure of E coli pstSCAB in the catalytic intermediate state

Cryo-EM structure of DCL4-Hairpin RNA complex

Cryo-EM structure of E coli pstSCAB in the pretranslocation state

Cryo-EM structure of DCL4-DRB4CTD-dsRNA complex

CryoEM map of recombinant human MCM SH with MCM3 WT

Structure of compacted DNA-free MCM DH at 3.9 Angstroms resolution

Structure of the human TREX-2 bound to UAP56

CryoEM map of recombinant human MCM SH with MCM3 I804A/F806A/I808A

Structure of DNA-free MCM SH at 3.2 Angstroms resolution

Structure of extended DNA-free MCM DH at 3.8 Angstroms resolution

The structure of NCP-motor-ARP module of ncBAF-nucleosome complex

The structure of ARP module in ncBAF complex

The structure of NCP-RA module of ncBAF-nucleosome complex

The overall structure of ncBAF bound to the nucleosome

Cryo-EM structure of Fks2 in complex with enfumafungin

Cryo-EM structure of Fks1 in complex with enfumafungin

Cryo-EM structure of Fks1 with intact active site

Cryo-EM structure of Fks1 in apo state

mouse PDCD5-TRiC-ADP complex

Cryo-EM structure of Fks2 with intact active site

Cryo-EM structure of Fks1 in open state

Cryo-EM structure of Fks2 in apo state

BTN2A1-BTN3A1-BTN3A2 oligomer complex

Cryo-EM structure of BTN2A1-BTN3A1-BTN3A2 mutant (BTN3A1 H381R, BTN2A1 R477A/T510A) in complex with Vgamma9-Vdelta2 TCR (G115 genotype)

Structure of the honeybee GABAA RDL receptor with GABA and Abamectin

PSI-LHCI supercomplex binding with 4 Lhcas from M. polymorpha

Structure of bacteriophage T4 protal-neck protein gp20-gp13-gp14-Hfq assembled in vitro in C6 symmetry

Structure of bacteriophage T4 neck protein gp13 and gp14 and Hfq assembled in vitro in C6 symmetry

Integrin alpha-v beta-3 in complex with Trimucrin

Structure of bacteriophage T4 neck protein gp13 and gp14 assembled in vitro in C6 symmetry

Structure of bacteriophage T4 protal-neck mismatch complex gp20-gp14-gp13 assembled in vitro in C6 symmetry

Complex structure of influenza hemagglutinin HA stem with CR9114 Fab and FISW84 Fab

PSI-4 LHCI dimer supercomplex from M. polymorpha

Inward-open Structure of human B0AT1

Cryo-EM structure of dopamine bound mut-beta2-Adrenergic Receptor beta2R-M16-miniGs-Gbeta1gamma2-Nb35-scFv16 complex

Cryo-EM structure of epinephrine bound dopamine receptor 1 D1R-M74-miniGs-Gbeta1gamma2-Nb35 complex

Cryo-EM Structure of Human Tie2/minibinder tw1102_4 helices Complex

Glycogen phosphorylase dimer from E. coli

Glycogen phosphorylase from Segatella copri bound to glycogen-chain A and E

Glycogen phosphorylase from Segatella copri

Cryo-EM structure of glycogen phosphorylase from Dorea longicatena (monomer form)

Cryo-EM structure of glycogen phosphorylase from Dorea longicatena (dimer form)

Glycogen phosphorylase from Segatella copri decamer in complex with AMP

Glycogen phosphorylase dimer from E. coli in complex with glycogen

Glycogen phosphorylase from Segatella copri bound to glycogen-pentamer

A focused Cryo_EM structure of LA_PTH_PTH1R_Beta_arrestin1 complex(state 1 conformation)

A Cryo_EM structure of LA_PTH_PTH1R_Beta_arrestin1 complex(state 2 conformation)

Cryo-EM map of glycogen phosphorylase from Dorea longicatena (monomer form with extra density)

R583A mutant of glycogen phosphorylase from Segatella copri in the presence of AMP

R583A mutant of glycogen phosphorylase from Segatella copri

Glycogen phosphorylase from Segatella copri in complex with AMP

Glycogen phosphorylase from Segatella copri pentamer in complex with AMP chains D and E

In situ cryo-ET tomogram of lysosomes in BAPTA AM pre-treated (50uM, 30min) and LLOMe (0.5mM, 60min) treated TMEM192-3xHA HeLa cell.

In situ cryo-ET tomogram of lysosomal structure in LLOMe-treated (0.5mM, 1h) rat hippocampal neuron.

In situ cryo-ET tomogram of lysosomes in E64d pre-treated (20uM, 30min) and LLOMe (0.5mM, 60min) treated TMEM192-3xHA HeLa cell.

In situ cryo-ET of lysosome damaged by LLOMe (0.5mM, 60min) encapsulated in an autophagosome in HeLa TMEM192-3xHA cell.

In situ cryo-ET tomogram of a lysosomal structure in untreated HeLa TMEM192-3xHA cell.

In situ cryo-ET subtomogram averaged map of Flotillin complex

In situ cryo-ET tomogram of lysosomal structure in untreated rat hippocampal neurons

In situ cryo-ET tomogram of lysosomes in LLOMe (0.5mM, 60min) treated TMEM192-3xHA HeLa cell.

In situ cryo-ET tomogram of lysosome damaged by LLOMe (0.5mM, 60min) in HeLa TMEM192-3xHA cell.

Structure of the gdTCR-Fab complex

Cryo-EM structure of PWWP domain deleted DNMT 3A2/3B3 in complex with a di-nucleosome

Cryo-EM structure of a membrane transport protein

Cryo-EM structure of a membrane transport protein

Amino-terminal domain for GluK2-0xNeto2 in the open state, in complex with the positive allosteric modulator BPAM344 and agonist kainate

Consensus map for GluK2-0xNeto2 in the open state, in complex with the positive allosteric modulator BPAM344 and agonist kainate

H5 hemagglutinin (A/Jiangsu/NJ210/2023) in complex with central stem-targeting Fab ST14

H1 hemagglutinin (A/California/04/2009) with E47K mutation in HA2 in complex with central stem-targeting Fab ST10

Coiled-coil bundlemer nanotube, R3K (15 proto-filaments)

Nanotube of computationally designed peptide assembly R3K (16 protofilament)

Amino-terminal domain for GluK2-2xNeto2 in the open state, in complex with the positive allosteric modulator BPAM344 and agonist kainate

H1 hemagglutinin (A/Michigan/45/2015) in complex with anchor-targeting Fab ST4

H1 hemagglutinin (A/Michigan/45/2015) in complex with anchor-targeting Fab ST15

Ligand-binding and transmembrane domains for GluK2-1xNeto2 in the open state, in complex with the positive allosteric modulator BPAM344 and agonist kainate

Ligand-binding and transmembrane domains for GluK2-0xNeto2 in the open state, in complex with the positive allosteric modulator BPAM344 and agonist kainate

Ligand-binding and transmembrane domains for GluK2-2xNeto2 in the open state, in complex with the positive allosteric modulator BPAM344 and agonist kainate

Consensus map for GluK2-1xNeto2 in the open state, in complex with the positive allosteric modulator BPAM344 and agonist kainate

Consensus map for GluK2-2xNeto2 in the open state, in complex with the positive allosteric modulator BPAM344 and agonist kainate

Amino-terminal domain for GluK2-1xNeto2 in the open state, in complex with the positive allosteric modulator BPAM344 and agonist kainate

L-cluster free apo-NifEN expressed in E. coli

Structure of tuco-tuco ribosome (rotated, tRNAs, and mRNA)

Structure of naked mole-rat ribosome (rotated, tRNAs, and mRNA)

Structure of tuco-tuco ribosome with P/E tRNA and eEF2 (rotated)

Structure of naked mole-rat ribosome with P/E tRNA and eEF2 (rotated)

L-cluster inward bound holo-NifEN expressed in E. coli

Gbg crosslinked to PLCb3 - second conformation

Structure of guinea pig ribosome with P/E-tRNA and mRNA

Negative stained A. vinelandii NifEN-B' fusion

Gbg crosslinked to PLCb3 - second conformation

Gb1g2 crosslinked to PLCb3

Negative stained A. vinelandii NifEN/NifH ADPxAIF4- stabilized complex

Structure of naked mole-rat ribosome (non-rotated)

Cryo-EM structure of the RC complex from Rhodospirillum rubrum

Cryo-EM structure of the LH1 complex from Roseiflexus castenholzii

Strand displacement state III of Human mitochondrial DNA polymerase gamma ternary complex

Strand displacement state II of Human mitochondrial DNA polymerase gamma ternary complex

Strand displacement state IV of Human mitochondrial DNA polymerase gamma ternary complex

80S Ribosome Rat Brain polysome fracAon. Class 2

80S Ribosome Rat Brain polysome fraction. Class 1

Strand displacement state I of Human mitochondrial DNA polymerase gamma ternary complex

The ER membrane protein complex acts as a chaperone to promote voltage-gated calcium channel assembly

Cryo-EM structure of EF-G and RaiA simultaneously bound to an E. coli ribosome imaged in a cell lysate

Native GABA-A receptor from rat cerebella, beta2-alpha1-beta2-alpha1-gamma2 subtype, in complex with GABA

Native GABA-A receptor from rat cerebella, beta2-alpha1-beta1-alpha6-gamma2 subtype, in complex with GABA

Native GABA-A receptor from rat cerebella, beta1-alpha1-beta2-alpha1-gamma2 subtype, in complex with GABA and PZ-II-029

Yeast Respiratory SuperComplex - deltaQCR6

Native GABA-A receptor from rat cerebella, beta2-alpha1-beta1-alpha6-gamma2 subtype, in complex with GABA and PZ-II-029

Native GABA-A receptor from rat cerebella, beta1-alpha1-beta1-alpha1-gamma2 subtype, in complex with GABA and PZ-II-029

Native GABA-A receptor from rat cerebella, beta2-alpha1-beta2-alpha1-gamma2 subtype, in complex with GABA and PZ-II-029

Yeast Respiratory SuperComplex - non uniform refinement

Native GABA-A receptor from rat cerebella, beta1-alpha1-beta2-alpha1-gamma2 subtype, in complex with GABA

In situ structure of the human mitoribosome in the P state

In situ structure of the human mitoribosome in the P-E state from TACO1-knockout cells

In situ structure of the human mitoribosome in the A-P state with TACO1

In situ structure of the human mitoribosome in the P-E state

In situ structure of the human mitoribosome in the A-P-E state with TACO1

Structure of anti-HEL AiTab

TLP-2g, a glycofibril obtained from a Karst cave from Guilin City, Guangxi Zhuang Autonomous Region, China

TLP-2a, a glycofibril obtained from a Karst cave from Guilin City, Guangxi Zhuang Autonomous Region, China

TLP-2h, a glycofibril obtained from a Karst cave from Guilin City, Guangxi Zhuang Autonomous Region, China

Structure of SARM1 bound to SIR3-ADPR

Pilus-like-alpha, a bacteria pilus-like structure obtained from a Karst cave from Guilin City, Guangxi Zhuang Autonomous Region, China

pilus-like-beta, a bacteria pilus-like structure obtained from a Karst cave from Guilin City, Guangxi Zhuang Autonomous Region, China

Human alpha7 nicotinic receptor in complex with the F1 nanobody

Cryo-EM map of SKM-70S ribosomal stalled complex in the major state (vacant A-site, canon)

Cryo-EM structure of aquaporin 3 at pH 5.5

Cryo-EM structure of aquaporin 3 at pH 8.0 with hydrogen peroxide

NetF - ANTXR2 local refinement focused

NetF 9mer pre-pore map on 2N2 nanodiscs.

Human alpha7 nicotinic receptor in complex with the E6 nanobody

NetF pore structure

Cryo-EM structure of aquaporin 3 at pH 8.0

NetF - ANTXR2 structure (C4)

Cryo-EM structure of SKM-70S ribosomal stalled complex in the A-tRNA positioned (Body open) state.

Cryo-EM structure of SKM-70S ribosomal stalled complex in the rotated state with hybrid tRNAs

Human 80S ribosome in complex with NatA in proximal and distal position

Human 80S ribosome in complex with NatA in distal position and Ebp1

Structure of photoactivated rhodopsin in complex with a megabody

In situ mitoribosome focused on the mtSSU

Consensus map of the mitoribosome complexed with TACO1

Membrane-associated human mitoribosome in complex with TACO1

CryoEM Structure of PHR-phosphatase-C2 domain of SHIP2

A membrane protein with cofactor determined by single-particle CryoEM

Cryo-EM structure of the HBsAg dimer and Complex with Fab

Cryo-EM structure of Euglenophyte photosystem I

Amino-terminal domain for GluK2 in the open state, in complex with the positive allosteric modulator BPAM344 and agonist kainate

Cryo-EM structure of human DNMT3A2-DNMT3B3 complex bound to a di-nucleosome with a five base pair linker

A focus of tetramer (2) of the cryo-EM structure of human DNMT3A2-DNMT3B3 complex bound to di-nucleosome

Cryo-EM structure a single nucleosome (2) focus of human DNMT3A2-DNMT3B3 complex bound to di-nucleosome

Cryo-EM structure of DNMT 3A2/3B3 tetramer in complex with a di-nucleosome with a six base pair linker

Ligand-binding and transmembrane domains for GluK2-0xNeto2 in the apo state with asymmetric ligand binding domain

Cryo-EM structure of DNMT 3A2/3B3 tetramer in complex with a di-nucleosome with K120R mutant H2B

A focus of DNMT tetramer (1) of the cryo-EM structure of human DNMT3A2-DNMT3B3 complex bound to di-nucleosome

Amino-terminal domain for GluK2-0xNeto2 in the apo state with asymmetric ligand binding domain

Ligand-binding and transmembrane domains for GluK2 in the open state, in complex with the positive allosteric modulator BPAM344 and agonist kainate

Negative stain of LukAB toxin in complex with Fab STAU-458

Cryo-EM structure of a di-nucleosome with an eight base-pair linker

Negative stain of LukAB toxin in complex with Fab STAU-477

Negative stain of LukAB toxin in complex with Fab STAU-17

Negative stain of LukAB toxin in complex with Fab STAU-463

The consensus model of the cryo-EM structure of human DNMT3A2-DNMT3B3 complex bound to di-nucleosome

Cryo-EM structure of a single nucleosome (1) focus of human DNMT3A2-DNMT3B3 complex bound to di-nucleosome

Cryo-EM structure of a di-nucleosome with a five base pair linker

Cryo-EM structure of human DNMT3A2-DNMT3B3 complex bound to a di-nucleosome and an histone-3 peptide

Negative stain of LukAB toxin in complex with Fab STAU-464

Negative stain of LukAB toxin in complex with Fab STAU-524

Helical assembly of AVAST5 filament

Consensus map for GluK2 in the open state, in complex with the positive allosteric modulator BPAM344 and agonist kainate

Cryo-EM structure of RNase P in cell lysates determined using the graffendor grid

Focus map of DNMT3A2/3B3 tetramer for Cryo-EM structure of DNMT3A2/3B3 in complex with 167H3K36me2-nucleosome

HsSTING with cGAMP/C53/DCA

Consensus map for GluK2-0xNeto2 in the apo state with asymmetric ligand-binding domain

Focus map of nucleosome for Cryo-EM structure of DNMT3A2/3B3 in complex with 167H3K36me2-nucleosome

Cryo-EM structure of SUDV glycoprotein with modified HR1c (L579P) and HR2 stalk bound to CA45 Fab

Consensus map for Cryo-EM structure of DNMT3A2/3B3 tetramer in complex with a 167H3K36me2 nucleosome

cryoEM structure of RNase MRP in yeast cell lysates using the Graffendor grid.

Focus map of nucleosome 2 for Cryo-EM structure of DNMT3A2/3B3 in complex with H3K36me2 di-nucleosome with eight base pair linker

Focus map of PWWP_2 for Cryo-EM structure of DNMT3A2/3B3 in complex with 167H3K36me2-nucleosome

CryoEM structure of capsid from human astrovirus 1 in complex with human neonatal Fc receptor

Consensus map for Cryo-EM structure of DNMT3A2/3B3 in complex with H3K36me2 di-nucleosome with eight-base-pair linker

Focus map of nucleosome 1 for Cryo-EM structure of DNMT3A2/3B3 in complex with H3K36me2 di-nucleosome with eight base pair linker

Focus map of PWWP_1 domain for Cryo-EM structure of DNMT3A2/3B3 in complex with 167H3K36me2-nucleosome

Focus map of nucleosome1_PWWP1 for Cryo-EM structure of DNMT3A2/3B3 in complex with H3K36me2 di-nucleosome with eight base pair linker

Focus map of DNMT3A2/3B3 tetramer2 for Cryo-EM structure of DNMT3A2/3B3 in complex with H3K36me2 di-nucleosome with eight base pair linker

Focus map of DNMT3A2/3B3 tetramer1 for Cryo-EM structure of DNMT3A2/3B3 in complex with H3K36me2 di-nucleosome with eight base pair linker

CryoEM structure of human astrovirus 1 spike in complex with human neonatal Fc receptor

IN-ML-15 bound to IRzip

IN-ML-15 bound to IGF1Rzip

native GluN1/N2B/NX-consensus map in the closed state

native GluN1_NX_consensus_map

native GluN1/N2B-subtype1 in closed state

native GluN1/N2A-S3 TMD focused map in the closed state

native GluN1/N2A-S3-consensus map in the closed state

native GluN1/N2A/N2B-s1 consensus map in the closed state

native GluN1/N2A-subtype2-TMD focused map

Structure of the flotillin complex in situ

native GluN1/N2A/N2B-s1-TMD focused map in the closed state

native GluN1_NX TMD focused map

native GluN1/N2A-subtype2-consensus map

native GluN1/N2A/N2B-subtype2 consensus map in the closed state

native GluN1/N2B-TMD-focused map in the closed state

native GluN1/N2A/N2B-S2-TMD focused map in the closed state

native GluN1/N2B receptor consensus map in the closed state

native GluN1/N2A-subtype 1-TMD focused

native NMDA receptor-GluN1/N2A/N2B-S1 in the closed state

native GluN1/N2B receptor in the fully open state

native GluN1/N2B receptor in the open state TMD focused map

native NMDA receptor-GluN1/N2B/NX in the open state consensus map

native GluN1_N2A_NX_subtype-consensus map in the closed state

native GluN1/N2A/NX-TMD-focused map in the closed state

native NMDA receptor-GluN1/N2B/NX in inactive state consensus map

native NMDA receptor-GluN1/N2A in inactive state consensus map

native GluN1_N2A_NX_subtype1_composite_map in the closed state

native NMDA receptor-GluN1/N2A/N2B in inactive state consensus map

native GluN1_GluNX composite map

native GluN1_N2A_NX_subtype2_TMD_focused

native GluN1_N2A_NX_subtype2_composite map

native NMDA receptor-GluN1/N2B/NX in the open state TMD focused map

native native NMDA receptor-GluN1/N2B in inactive state TMD focused map

native GluN1_N2A_NX_subtype1_TMD_focused map in the closed state

native GluN1_N2A_NX_S2_consensus map

native NMDA receptor-GluN1/N2A in inactive state TMD focused map

native NMDA receptor-GluN1/N2B in the inactive state consensus map

native NMDA receptor-GluN1/N2B/NX in the open state

native GluN1/N2B/NX composite map in the closed state

native NMDA receptor-GluN1/N2B/NX in inactive state TMD focused map

native NMDA receptor-GluN1/N2A/N2B in inactive state TMD focused map

native NMDA receptor-GluN1/NX consensus map

native NMDAR receptor-GluN1/N2B in the inactive state

native NMDA receptor-GluN1-N2A-NX consensus map

native NMDA receptor-GluN1/N2A/NX composite map

native NMDA receptor-GluN1/NX TMD focused map

native NMDA receptor-GluN1/N2B/NX in inactive state

native NMDA receptor-GluN1/NX composite map

native NMDA receptor-GlUN1/N2A/NX TMD focused map

native NMDA receptor-GluN1/N2A-S1 in closed state

native NMDA receptor-GluN1/N2A/2B in inactive state

native NMDA receptor-GluN1/N2B in the open state

native NMDA receptor-GluN1/N2B in the closed state

native NMDA receptor-GluN1/N2A in the inactive state

native NMDA receptor-GluN1/N2A-S2 in the closed state

native NMDA receptor-GluN1/N2A/N2B-S2 in the closed state

native NMDA receptor-GluN1/N2A-S3 in the closed state

pilus-like-gamma, a bacteria pilus-Like structure obtained from a Karstcave from Guilin city, Guangxi ZhuangAutonomous Region, China

TLP-2f, a glycofibril obtained from a Karst cave from Guilin City, Guangxi Zhuang Autonomous Region, China

Subtomogram average of the Chlamydomonas reinhardtii chlororibosome - chimeric map

Structure of Oceanobacillus iheyensis group II intron domains D1-D6

Structure of the Chlamydomonas reinhardtii chlororibosome with P-site tRNA - consensus map

Subtomogram average of the Chlamydomonas reinhardtii chlororibosome - SSU extension focused

Structure of the Chlamydomonas reinhardtii chlororibosome - SSU head extension recenter and focus

Structure of the Chlamydomonas reinhardtii chlororibosome - SSU head focus

Structure of the Chlamydomonas reinhardtii chlororibosome - SSU extension focus

Structure of the Chlamydomonas reinhardtii chlororibosome - LSU focus

Structure of the Chlamydomonas reinhardtii chlororibosome

Structure of the Chlamydomonas reinhardtii chlororibosome - LSU L7/12 stalk focus

Subtomogram average of the membrane-bound Chlamydomonas reinhardtii chlororibosome

Structure of the Chlamydomonas reinhardtii chlororibosome - LSU CP focus

Structure of the Chlamydomonas reinhardtii chlororibosome - SSU body focus

Structure of the Chlamydomonas reinhardtii chlororibosome with pY factor - LSU focus

Subtomogram average of the Chlamydomonas reinhardtii chlororibosome - LSU focused

Structure of the Chlamydomonas reinhardtii chlororibosome with P-site tRNA - LSU focus

Subtomogram average of the Chlamydomonas reinhardtii chlororibosome - SSU focused

Structure of the Chlamydomonas reinhardtii chlororibosome with pY factor - consensus map

Structure of the Chlamydomonas reinhardtii chlororibosome - consensus map

Subtomogram average of the Chlamydomonas reinhardtii chlororibosome - consensus map

Structure of the Chlamydomonas reinhardtii chlororibosome with pY factor - focus SSU

Structure of the Chlamydomonas reinhardtii chlororibosome with P-site tRNA - focus SSU

Cas9 in complex with tracrRNA and crRNA, Streptococcus thermophilus DGCC 7710 CRISPR3 system

Cas9-Cas1-Cas2-Csn2 supercomplex with dsDNA in PAM-unbound conformation, Streptococcus thermophilus DGCC 7710 CRISPR3 system

PAM-bound Cas9-Cas1-Cas2-Csn2 supercomplex in the locked conformation, Streptococcus thermophilus DGCC 7710 CRISPR3 system

Csn2 (point mutations Y212R, I213R and M215R) in complex with Cas1-Cas2 integrase and dsDNA, Streptococcus thermophilus DGCC 7710 CRISPR3 system

PAM-bound Cas9-Cas1-Cas2-Csn2 supercomplex in the docked conformation, Streptococcus thermophilus DGCC 7710 CRISPR3 system

PAM-bound Cas9-Cas1-Cas2-Csn2 supercomplex in the docked conformation, Streptococcus thermophilus DGCC 7710 CRISPR3 system

PAM-bound Cas9-Cas1-Cas2-Csn2 supercomplex in the locked conformation, Streptococcus thermophilus DGCC 7710 (consensus map)

Cas9-Cas1-Cas2-Csn2 supercomplex with dsDNA in PAM-unbound conformation, Streptococcus thermophilus DGCC 7710 CRISPR3 system

Cas9-Cas1-Cas2-Csn2 supercomplex with dsDNA in PAM-unbound conformation, Streptococcus thermophilus DGCC 7710 CRISPR3 system

Cas9:crRNA:tracrRNA in complex with PAM-containing non-cognate DNA, PAM-bound conformation, Streptococcus thermophilus DGCC 7710 CRISPR3 system

PAM-bound Cas9-Cas1-Cas2-Csn2 supercomplex in the docked conformation, Streptococcus thermophilus DGCC 7710 CRISPR3 system

Cas1-Cas2 CRISPR integrase bound to prespacer and target DNA, Streptococcus thermophilus DGCC 7710 CRISPR3 system

Cryo-EM structure of activated retron Eco2 (Ec67)

PAM-bound Cas9-Cas1-Cas2-Csn2 supercomplex in the locked conformation, Streptococcus thermophilus DGCC 7710 CRISPR3 system

PAM-bound Cas9-Cas1-Cas2-Csn2 supercomplex in the locked conformation, Streptococcus thermophilus DGCC 7710 CRISPR3 system

Cas9-Cas1-Cas2-Csn2 supercomplex with dsDNA in PAM-unbound conformation, Streptococcus thermophilus DGCC 7710 CRISPR3 system

Cas9:crRNA:tracrRNA in complex with PAM-containing non-cognate DNA, PAM-unbound conformation, Streptococcus thermophilus DGCC 7710 CRISPR3 system

Partial Cas1-Cas2 CRISPR integrase complex bound to a half-integration product, Streptococcus thermophilus DGCC 7710 CRISPR3 system

Cas1-Cas2 CRISPR integrase bound to prespacer DNA, Streptococcus thermophilus DGCC 7710 CRISPR3 system

PAM-bound Cas9-Cas1-Cas2-Csn2 supercomplex in the docked conformation, Streptococcus thermophilus DGCC 7710 CRISPR3 system

Cryo-EM structure of ternary complex BCL6-CRBN-DDB1 with BMS-986458 (local refined), a potent and selective BCL6 ligand directed degrader (LDD)

Cryo-EM structure of apo GPR50 with BRIL fusion, anti-BRIL Fab, and anti-Fab Nb complex

NER dual incision complex - DuIS local ARF map

NER dual incision complex - noG focused Core7 map

NER dual incision complex - DuIM local AF map

NER dual incision complex - DuIS local Bot map

NER dual incision complex - DuIS consensus map

NER dual incision complex - DuIM local DG map

NER dual incision complex - DuIM local Bot62 map

NER dual incision complex - DuIM local AR map

NER dual incision complex - noG focused XPC map

NER complex - C7CAD.ATP

NER dual incision complex - DuIS local DG map

NER dual incision complex - DuIS

NER dual incision complex - NoF

NER dual incision complex - DuIM consensus map

NER dual incision complex - DuIM

Composite map for Cryo-EM structure of DNMT3A2-DNMT3B3 tetramer bound to 167H3K36me2-nucleosome

Cryo-EM structure of DNMT3A2/3B3 in complex with H3K36me2 di-nucleosome with eight base pair linker

KICSTOR-GATOR1 complex (SZT2 [2800-3432], C12orf66) focused refinement

KICSTOR-GATOR1 complex (SZT2 [1300-2400]) focused refinement

Bacteriophage Ur-lambda TypeIIb infection complex

In situ structure of human mitoribosome in the A/T-P state from TACO1-knockout cells

In situ structure of the human mitoribosome in the P state from TACO1-knockout cells

KICSTOR-GATOR1 (DEPDC5, NPRL2, NPRL3) focused refinement

KICSTOR-GATOR1 complex (SZT2 [2000-3200], KPTN, ITFG2) focused refinement

In Situ Structure of the Human Mitochondrial Large Subunit 39S in Complex with TACO1

Bacteriophage Ur-lambda TypeIIa infection complex

In Situ Structure of the Human Mitoribosome Large Subunit 39S in Complex with EF-Tu

KICSTOR-GATOR1 (SZT2 [1-2000], NPRL3) focused refinement

KICSTOR-GATOR1 dimer supercomplex (SZT2, NPRL2, NPRL3) focused refinement

The KICSTOR-GATOR1 complex

KICSTOR-GATOR1 dimer supercomplex (DEPDC5) focused refinement

In situ structure of the human mitoribosome in the A-P state from TACO1-knockout cells

In situ structure of the human mitoribosome in the A/P-P/E state from TACO1-knockout cells

In situ structure of the human mitoribosome in the A/T-P-E state from TACO1-knockout cells

In situ structure of the human mitoribosome in the A-P-E state from TACO1-knockout cells

In situ structure of the human mitoribosome in the A/P-P/E state

ESIBD structure of GroEL

Transient activated state of BetP

Transient activated state of BetP in complex with betaine

EAAT1 thermostabilized mutant in Complex with L-Asp, Metal Ions, and the allosteric inhibitor UCPH101 in Salipro

Glutamate transporter homologue GltPh mutant P206R in Complex with L-Aspartate and Sodium Ions in Salipro

Upregulated state of BetP in potassium

Cryo-electron tomogram of cryo-FIB milled Nostoc PCC7120 cseKO

Cryo-electron tomogram of cryo-FIB milled Nostoc PCC7120 wild-type

Upregulated state of BetP with Potassium in Amphipol A8-35

Downregulated state of the betaine transporter BetP

GBSV1 portal protein without the N-terminal tail

EAAT1 thermostabilized mutant in Complex with Rubidium, and the allosteric inhibitor UCPH101 in DDS/CHS

Cryo-electron tomogram of cryo-FIB milled Nostoc PCC7120 cse KO

Inward-open structure of human GABA transporter 3 bound to selective inhibitor SR-THAP