EMD-76772

Single-particle
2.91 Å
EMD-76772
3D View Gallery
Deposition: 20/04/2026
Map released: 30/09/2026
Last modified: 30/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-76772

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-12uu summary report (pdf.gz) Map-12uu FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

The AAV2 capsid in complex with IgG-Fab#3-4

EMD-76772

Single-particle
2.91 Å
EMD-76772
3D View Gallery
Deposition: 20/04/2026
Map released: 30/09/2026
Last modified: 30/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: adeno-associated virus 2, Homo sapiens
Sample: AAV2 capsid in complex with IgG-Fab3-2
Fitted models: 12uu

Deposition Authors: Zachery J, Mietzsch M, McKenna R

Broadly cross-reactive anti-capsid IgA is an overlooked antibody 1 barrier in AAV2 mediated gene transfer
Logan GJ, Khandekar N, Hall B, Zachery J, Mandwie M, Hsi-Bell J, Huang A, Vyas K, Anderson D, Knight M, Farrar MA, Lisowski L, Reed JH, Mietzsch M, McKenna R, Alexander IE
(2026) Nat Commun
ISSN: 2041-1723