EMD-67037

Single-particle
2.74 Å
EMD-67037
3D View Gallery
Deposition: 12/11/2025
Map released: 30/09/2026
Last modified: 30/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-67037

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9xn3 summary report (pdf.gz) Map-9xn3 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Glucose-dependent insulinotropic polypeptide receptor-Gs complex activated by the small molecule agonist SIM1

EMD-67037

Single-particle
2.74 Å
EMD-67037
3D View Gallery
Deposition: 12/11/2025
Map released: 30/09/2026
Last modified: 30/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Bos taurus, Rattus norvegicus, Lama glama
Sample: Glucose-dependent insulinotropic polypeptide receptor-Gs complex activated by the small molecule agonist SIM1
Fitted models: 9xn3

Deposition Authors: Xu HE, Shan H, He Q, Zhao L
Structural basis for small-molecule agonism at GCGR and GIPR via a conserved intracellular allosteric site.
He Q, Shan H, Hu W, Eric Xu H, Zhao LH
(2026) Acta Pharmacol.Sin.
PUBMED: 42736455
DOI: doi:10.1038/s41401-026-01923-5
ISSN: 1745-7254