EMD-74472

Single-particle
2.7 Å
EMD-74472
3D View Gallery
Deposition: 15/12/2025
Map released: 30/09/2026
Last modified: 30/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-74472

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Raw consensus map of RyR1 in presence of rosuvastatin (including auxiliary transmembrane helices TMx1 and TMx2; Ca2+/CFF/ATP dataset; closed pore)

EMD-74472

Single-particle
2.7 Å
EMD-74472
3D View Gallery
Deposition: 15/12/2025
Map released: 30/09/2026
Last modified: 30/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Oryctolagus cuniculus
Sample: Complex of RyR1 with Calstabin-1 in presence of rosuvastatin (Ca2+/CFF/ATP condition)

Deposition Authors: Weninger G, Marks AR
Structural basis for rosuvastatin-induced activation of skeletal muscle ryanodine receptor 1
Weninger G, Reiken S, Yuan Q, Miotto MC, Chang A, Liu Y, Wronska A, Dridi H, Marks AR
(2026) Nat Commun
DOI: doi:10.1038/s41467-026-77372-9
ISSN: 2041-1723